Hydroxypyl methylcellose (hpmc)Shin sel mai kyau ne na baƙon abu tare da kyakkyawan fim-form, m, m, m, m, kuma ana amfani dashi a cikin masana'antar magunguna. A matsayinka na magunguna na magunguna, ana iya amfani da Driscincel®hpmc a Allunan, Capsules, dorewa shirye-shiryen saki, shirye-shiryen saki, tsarin isar da magani.
1. Projecticochemical kadarorin HPMC
HPMC shine kayan polymer na semi-lylolating ta methylating da hydroxypropylatat na halitta na halitta, tare da mafi kyawun lasrin ruwa da kuskure. Siadarinsa ba shi da ƙimar zazzabi da ƙimar PH, kuma yana iya kumburi cikin ruwa don samar da mafita ta viscous, wanda ke taimaka wa saki kwayoyi. Dangane da danko, HPMC za a iya raba shi zuwa rukuni uku: Low MPAChara (5-100 MPALNA (5-4000 MPACHE) da babban danko (4000000 MPAM), waɗanda suka dace da su Abubuwan da ake shirye-shiryen daban-daban.
2. Aikace-aikacen HPMC a cikin shirye-shiryen magunguna
2.1 Aikace-aikace a Allunan
Za'a iya amfani da HPMC azaman mai ban sha'awa, rushewa, shafi kayan da sarrafawa-saki kwayoyin halitta a cikin allunan.
Binder:Za'a iya amfani da HPMC azaman mai ba da gunkumin rigar ko bushewa don haɓaka ƙarfin barbashi, taurin kwamfutar hannu da kwanciyar hankali na kwayoyi.
Wurantragrant:Za'a iya amfani da ƙarancin HPMC a matsayin wulakanci don inganta rarraba kwamfutar hannu da ƙara yawan ɓuya miyagun ƙwayoyi bayan kumburi da ruwa.
Shafi kayan:HPMC na ɗaya daga cikin manyan kayan shafi na kwamfutar hannu, wanda zai inganta bayyanar kwayoyi, rufe mummunan dandano na kwayoyi ko za a iya amfani da shi a cikin orating tare da filastik.
Za'a iya amfani da kayan saki: Za'a iya amfani da HPMC mai ƙarfi azaman kayan aikin kwarangwal don jinkirta da magani da kuma cimma ko sarrafawa ko sarrafawa. Misali, HPMC K4m, HPMC K15m da HPMC K100m ana amfani dasu don shirya allunan saki mai sarrafawa.
2.2 aikace-aikace a cikin shirye-shiryen capsule
Za'a iya amfani da HPMC don samar da capsules na tsire-tsire da aka samo don maye gurbin Gelatin Capsules, wanda ya dace da masu cin ganyayyaki da mutanen da ke rashin lafiyar da aka samo. Bugu da kari, za a iya amfani da HPMC don cike ruwa ko semisolid capsules don inganta kwanciyar hankali da halayen kwayoyi na kwayoyi.
2.3 aikace-aikace a cikin shirye-shiryen ophthalmic
HPMC, kamar yadda babban bangaren hawaye, zai iya ƙara danko na wucin gadi, zai iya ƙara danko na ido saukad, tsawaita lokacin zama na kwayoyi akan ocular surface, da kuma inganta bioavailability. Bugu da kari, ana iya amfani da HPMC don shirya gwal gwal, fina-finai na ido, da dai sauransu, don inganta tasirin sakin kwayoyi masu kyau.
2.4 Aikace-aikacen Aikace-aikacen Isar da Magunguna
Drminchpmc yana da kyawawan kayan fim da biocompativity, kuma ana iya amfani dashi don shirya facin canji, gels da creams. Misali, a cikin tsarin isar da tsarin miyagun ƙwayoyi, ana iya amfani da HPMC azaman kayan matrix don ƙara yawan adadin shigarwar fuka-fukai kuma tsawan tsawon lokacin aiki.
2.5 aikace-aikace a cikin baka na baka da dakatarwa
Za'a iya amfani da HPMC azaman Thaferener da kuma tsayayye don inganta kayan aikin na fure da dakatarwa, da haɓaka daidaituwa da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali da kwanciyar hankali.
2.6 aikace-aikace a cikin shirye-shiryen inhan
Za'a iya amfani da HPMC azaman mai ɗaukar ruwa don bushewar kayan shaye-shaye (DPIS) don inganta ruwan sha da watsawa da ƙwayoyin cuta, kuma don haka haɓaka tasirin warkewa.
3. Abincewar HPMC a cikin shirye-shiryen saki
HPMC yana da halaye masu zuwa azaman mai ɗaukar nauyi mai ɗorewa:
Kyakkyawan ruwa mai kyau:Zai iya tsalle cikin ruwa da sauri don samar da shamaki na gel kuma yana tsara farashin sakin magani.
Kyakkyawan Biocompciativity:Rashin guba da rashin haushi, ba jikin mutum ba, ba a sha ba, kuma yana da bayyananniyar hanya mai kyau.
Ingantaccen daidaitawa:Ya dace da nau'ikan kwayoyi daban-daban, ciki har da magungunan ruwa mai narkewa.
Tsari mai sauƙi:Ya dace da yawancin hanyoyin aiwatar da shirye-shiryen da ke kai tsaye kamar tebur na kai tsaye.
A matsayin mai mahimmanci magunguna,HpmCAna amfani da shi sosai a cikin filayen da yawa kamar Allunan, capsules, ophthmalmic shirye-shiryen saki. A nan gaba, tare da ci gaba da ci gaba da ci gaban fasahar shirye-shiryen shirye-shiryen Pharmaceututical, ana samar da samar da masana'antu tare da ingantattun zaɓuɓɓuka masu kyau.
Lokacin Post: Feb-08-2025