HPMC (hydroxypropyl methylcellulose) wani abu ne na polymer mai narkewa da ruwa wanda aka yi amfani da shi sosai a fagen gini, magunguna, abinci da sinadarai na yau da kullun. Yana da kyau thickening, emulsification, film-forming, m colloid da sauran Properties. A cikin tsarin emulsion, HPMC na iya sarrafa danko na emulsion ta hanyoyi daban-daban.
1. Tsarin kwayoyin halitta na HPMC
Dankowar HPMC ya fi shafar nauyin kwayoyin sa da matakin maye gurbinsa. Mafi girman nauyin kwayoyin halitta, mafi girma da danko na maganin; da kuma matakin maye gurbin (wato, matakin maye gurbin hydroxypropyl da ƙungiyoyin methoxy) yana rinjayar solubility da danko Properties na HPMC. Musamman, mafi girman matakin maye gurbin, mafi kyawun narkewar ruwa na HPMC, kuma danko yana ƙaruwa daidai da haka. Masu sana'a yawanci suna ba da samfuran HPMC tare da ma'aunin kwayoyin halitta daban-daban da digiri na maye gurbin don biyan buƙatun aikace-aikace daban-daban.
2. Yi amfani da maida hankali
Haɗin kai na HPMC a cikin maganin ruwa yana ɗaya daga cikin mahimman abubuwan da ke shafar danko. Gabaɗaya magana, mafi girman maida hankali na HPMC, mafi girman ɗankowar maganin. Koyaya, danko na nau'ikan HPMC daban-daban a taro iri ɗaya na iya bambanta sosai. Sabili da haka, a cikin aikace-aikacen aiki, ya zama dole don zaɓar ingantaccen taro na maganin HPMC bisa ga takamaiman buƙatun danko. Misali, a aikace-aikacen gine-gine, yawanci ana sarrafa maida hankali na HPMC tsakanin 0.1% da 1% don samar da ɗankowar aiki mai dacewa da aikin gini.
3. Hanyar rushewa
Tsarin rushewar HPMC kuma yana da tasiri mai mahimmanci akan danko na ƙarshe. HPMC yana da sauƙin tarwatsawa a cikin ruwan sanyi, amma yawan narkewa yana jinkirin; yana narkewa da sauri a cikin ruwan zafi, amma yana da sauƙi don haɓakawa. Don guje wa tashin hankali, ana iya amfani da hanyar ƙara sannu a hankali, wato, da farko a hankali ƙara HPMC a cikin ruwan sanyi don tarwatsa, sannan a zafi da motsawa har sai ya narke gaba daya. Bugu da kari, HPMC kuma za a iya premixed tare da sauran busassun foda sa'an nan kuma ƙara zuwa ruwa don narke don inganta narkewa yadda ya dace da danko kwanciyar hankali.
4. Zazzabi
Zazzabi yana da tasiri mai mahimmanci akan danko na mafita na HPMC. Gabaɗaya, dankowar maganin HPMC yana raguwa yayin da yawan zafin jiki ke ƙaruwa. Wannan saboda hauhawar zafin jiki zai raunana haɗin gwiwar hydrogen tsakanin kwayoyin halitta, yana sa sarkar kwayoyin halitta ta HPMC zamewa cikin sauƙi, ta haka yana rage dankowar maganin. Sabili da haka, a cikin aikace-aikacen da ke buƙatar babban danko, ana amfani da mafita na HPMC a ƙananan yanayin zafi. Misali, a cikin aikace-aikacen magunguna, ana amfani da mafita na HPMC sau da yawa a cikin zafin jiki don tabbatar da kwanciyar hankali da ingancin maganin.
5. pH darajar
Hakanan ƙimar pH ta shafi dankowar maganin HPMC. HPMC yana da mafi girman danko a ƙarƙashin tsaka tsaki da ƙarancin acidic, yayin da danko zai ragu sosai ƙarƙashin ƙaƙƙarfan yanayin acidic ko alkaline. Wannan shi ne saboda matsananciyar ƙimar pH za ta lalata tsarin kwayoyin halitta na HPMC kuma ya raunana tasirin sa. Sabili da haka, a cikin aikace-aikace masu amfani, ƙimar pH na maganin yana buƙatar sarrafawa da kiyaye shi a cikin tsayayyen kewayon HPMC (yawanci pH 3-11) don tabbatar da tasirin sa. Misali, a cikin aikace-aikacen abinci, ana amfani da HPMC sau da yawa a cikin abinci na acidic kamar yogurt da ruwan 'ya'yan itace, kuma ana iya samun ingantaccen danko ta hanyar daidaita ƙimar pH.
6. Sauran additives
A emulsion tsarin, da danko na HPMC kuma za a iya gyara ta ƙara sauran thickeners ko kaushi. Misali, ƙara adadin gishirin da bai dace ba (kamar sodium chloride) na iya ƙara ɗanƙon maganin HPMC; yayin da ƙara kwayoyin kaushi irin su ethanol zai iya rage danko. Bugu da ƙari, idan aka yi amfani da su tare da sauran masu kauri (kamar xanthan danko, carbomer, da dai sauransu), danko da kwanciyar hankali na emulsion kuma za a iya ingantawa sosai. Saboda haka, a cikin ainihin ƙirar ƙira, ana iya zaɓar abubuwan da suka dace kamar yadda ake buƙata don haɓaka danko da aikin emulsion.
HPMC na iya cimma daidaitaccen iko na dankowar emulsion ta hanyar tsarin kwayoyin halitta, maida hankali mai amfani, hanyar rushewa, zazzabi, ƙimar pH da ƙari. A aikace aikace, waɗannan abubuwan suna buƙatar a yi la'akari da su gabaɗaya don zaɓar nau'in HPMC da suka dace da yanayin amfani don cimma ingantaccen sakamako mai kauri. Ta hanyar ƙirar ƙirar kimiyya da sarrafa tsari, HPMC na iya taka muhimmiyar rawa a fannonin gini, magunguna, abinci da sinadarai na yau da kullun, samar da kyakkyawan aiki da ƙwarewar mai amfani.
Lokacin aikawa: Yuli-17-2024