Hydroxypyl methyl pelululose a matsayin mai compceuticical comptipient

Hydroxypyl methyl selululose (hpmc)Shin an yi amfani da maganin magunguna na antatatile sosai a cikin kayan sashi daban-daban saboda na musamman kaddarorin sa. Wannan ana samo asali ne daga pellose, a zahiri abin da ke faruwa a zahiri wanda aka samo a tsirrai, kuma an gyara su ta hanyar halayen sunadarai don samun halaye masu son. A cikin magunguna na magunguna, HPMC tana ba da sabis na mahara, gami da Binder, Fim, da Thicker, da wakilin saki, da kuma sakin wakili. A aikace-aikacensa da mahimmanci a masana'antar masana'antu gallake fahimtar fahimtar abubuwan da kaddarorinta, aikace-aikace, da fa'idodi.

Kayan HPMC da kayan haɗin gwiwar danko suna sa shi kyakkyawan zaɓi don sarrafa magani saki a cikin ɗan ƙaramin siffofin. Yana samar da wani matrix gel a kan hydration, wanda zai iya bunkasa sakin magani ta hanyar yadewa ta hanyar kumburin gel na kumburi. Maganin gel ya dogara da abubuwanda ke da nauyi, digiri na canzawa, da kuma maida hankali na HPMC a cikin tsari. Ta hanyar canza waɗannan sigogi, masana kimiyyar harhada magunguna zasu iya sakin bayanan sakin magunguna don cimma burin sakamakon warkewa da ake so, kamar sakin nan da nan.

Ana amfani da HPMC azaman mai ƙwarewa a cikin tsarin kwamfutar hannu don haɓaka haɗin kai da haɓaka ƙarfin kayan adon hannu. A matsayin m, yana inganta masarar adon da granulle samarwa yayin aiwatar da tsarin matsawa na kwamfutar, wanda ya haifar da abubuwan da aka lalata a daidai. Bugu da ƙari, fim ɗin fim ɗin HPMC-forming Properties sanya shi dace da shafi Allunan, wanda ya dace da nau'ikan masking, kariyar danshi, da kuma gyara sakin magani.

Baya ga baka mai kauri na baka, HPMC ta sami aikace-aikace a wasu magunguna na magunguna, gami da mafita na ophthmic, da facin ophthmic, da facin canji, da kuma sakin canji. A cikin mafita na ophthalmic mafita, HPMC yana aiki a matsayin mai danko - Ingantaccen wakili, Inganta lokacin zama na tsari a saman octuling. A cikin manyan gwal, yana samar da ikon rheunteriory, yana ba da damar sauƙin aikace-aikace da haɓaka shigar da fata na kayan aiki.

HpmC-Base InterderMal faci na bayar da tsarin bayar da magani mai dacewa da rashin haihuwa don tsarin tsari ko na karkara. Polymer Matrix yana sarrafa magunguna ta hanyar fata a kan tsawan lokaci, rike matakan warkewa a cikin jini yayin rage yawan hawa. Wannan shi ne musamman m don kwayoyi tare da kunkuntar windows ko wadataccen bincike na ci gaba.

HPMC na biocativicatilaci da rashin daidaituwa yana sa ta dace da amfani da su a cikin tsarinta na iyaye a matsayin wakili ko mai nuna ra'ayi. A cikin sakin-saki-saki da Micropheres ko nanoparticles na iya fadada kwayoyin ƙwayoyin cuta, samar da ci gaba da sakin daskararren lokaci, ta hanyar inganta yarda mai haƙuri.

HPMC ta nuna kaddarorin mucoadheres, yin amfani da shi da amfani a cikin tsari wanda aka tsara don isar da miyagun ƙwayoyi, kamar finafinan Buccal da tsirara. Ta hanyar bin Mucosal saman, HPMC prolongs lokacin zama, bada izinin inganta sha da magani da cizon kai.

An gano HPMC gaba ɗaya ta amintaccen (gras) ta hanyar hukumar abinci da kuma magunguna na Amurka (FDA), tana sa ta dace da amfani da su a cikin tsarin magunguna. A cikin yanayin halittarsa ​​da kuma yanayin rashin guba mai guba suna taimakawa ga rokonsa a matsayin compceuticical curifient.

Hydroxypyl methyl selululose (hpmc)Babban abin da ya fi dacewa da aikace-aikace ne da aikace-aikace daban-daban a duk fadin siffofin sashi daban-daban. Abubuwan da ke Musamman na musamman, gami da kariyar, danko, iyawar samar da fim, da biocompatibity, da biocawilability, da balisa ga tsarin miyagun ƙwayoyi da nufin cimma takamaiman manufofin warkewa. A matsayin binciken magunguna na ci gaba da bincike, HPMC na iya zama babban abin lura da tsarin samar da magani da kayan aikin asali.