Hydroxypyl methylcellose (hpmc) shine yanki mai narkewa wanda ba shi da ruwa mai narkewa wanda aka samu ta hanyar siginar sinadarai na sel na halitta. Ana amfani dashi sosai a cikin abinci, magani, kayan kwalliya da masana'antar gine-gine, musamman azaman adhesa, thickener, emulsifier da dakatar da wakilai. A cikin aikace-aikacen aikace-aikacen, da amincin halayen maganin hpmc yana da mahimmanci a aikinsa a fannoni daban-daban.
1. Tsarin da kaddarorin hydroxypyl methylcelhin
Tsarin kwayar halitta na hpmc ya ƙunshi ƙungiyoyi biyu masu maye, hydroxypropyl (-ch₂Chhch₃) da methyl (-Och₃), wanda ya sa ya sami kyakkyawan ruwa da ƙarfin canji. Sarkar HPMC kwayoyin halitta tana da wani madaidaiciyar tsari, amma yana iya samar da tsarin hanyar sadarwa mai tsayi a cikin mafita mai ruwa, wanda ya haifar da karuwa cikin danko. Nauyin kwayar halitta, nau'in m da kuma digiri na kayan maye (watau, darajar hydroxypropyl da methyl musictiontifultipropyl da methyl musanya kowane rukunin) yana da tasiri mai tasiri a kan danko na mafita.
2. Halayen halaye na ruwa
Halayen kayan haɗin gwiwa na maganin ruwan hpmc yana da alaƙa da abubuwan da aka tsara, nauyin kwayoyin, zafin jiki da ph tamanin na sauran ƙarfi. Gabaɗaya, ƙwarewar maganin hpmc mai iya ƙaruwa tare da haɓaka maida hankali. Ganinsa yana nuna rashin halaye na zamani da ba Newtiant na New-Newtian bane, kamar yadda kariyar ta karuwa, kariyar mafita a hankali ya ragu, yana nuna wani phenning phenning.
(1) tasirin taro
Akwai wata dangantaka tsakanin danko na danko na maganin hpmc ruwa mai ruwa da kuma maida hankali. Kamar yadda maida hankali ne na HPMC yana ƙaruwa, huldar kwayar halittar kwayoyin a cikin ruwa mai amfani da ruwa da ke haifar da karuwa da sarkar mafita. A ƙananan taro, danko na maganin bayani mai ruwa mai ruwa, amma a mafi girma taro, amma a mafi girma maida hankali, amma a mafi girma maida hankali ne, venction girma girma mafita yana zama lebur ne kuma ya kai darajar m.
(2) Tasirin nauyin kwayoyin halitta
Nauyin kwayar cutar kwayar cutar hpmc kai tsaye yana shafar danko na mafita mai ruwa. HPMC tare da nauyin ƙwayoyin ƙwayoyin cuta suna da sikarin kwayoyin halitta kuma na iya samar da tsari mai rikitarwa uku na tsarin sadarwa. Ya bambanta, HPMC tare da ƙananan ƙwayar ƙwayar ƙwayar cuta yana da tsarin cibiyar sadarwa mai kyau da ƙananan danko saboda ƙananan danko saboda ƙananan sarƙoƙin ta. Saboda haka, lokacin da ake amfani da shi, yana da matukar muhimmanci a zabi HPMC tare da nauyin kwayar halittar da ya dace don cimma sakamako mai kyau.
(3) sakamakon zazzabi
Zazzabi muhimmiyar mahimmanci tana shafar danko na maganin hpmc ruwa. Kamar yadda zafin jiki ya karu, motsi na kwayoyin kwararar ruwa suna ƙaruwa da danko na maganin yawanci ana ragewa. Wannan saboda lokacin da zazzabi ya tashi, da 'yancin kwayar cutar HPMC ta ƙaruwa da hulɗa tsakanin kwayoyin halittar da suka raunana, ta haka ne rage dankan mafita. Koyaya, amsar hpmc daga batuna daban-daban ko samfurori zuwa zazzabi na iya bambanta, don haka yanayin zafin jiki yana buƙatar gyara gwargwadon takamaiman buƙatun aikace-aikacen.
(4) sakamakon darajar pH
HPMC kanta fili ne na ba-ionic, kuma danko na mafita yana kula da canje-canje a cikin pH. Kodayake ya nuna nuna halin HPMC in mun gwada da kyawawan halaye a cikin yanayin acidic ko tsakaicin yanayin HPMC za a shafa a cikin matsanancin acidic ko alkalami. Misali, a karkashin mai karfi acid ko yanayin alkaline mai ƙarfi, za a iya lalata kwayoyin cutar HPMC ƙarfi, ta haka rage danko na ruwa mai ruwa.
3
Halin da ke cikin ilimin lissafi na bayani na HPMC yawanci yana nuna halaye na ruwa ba na Newकic ba, wanda ke nufin cewa danko baya da mahimmanci game da abubuwan da aka magance shi kamar nauyi na bayani, amma kuma nauyin kwayoyin ba shi da mahimmanci. Gabaɗaya magana, a lowarancin ƙimar kai, mafita HPMC mafi inganci yana nuna haɓakar ƙwarewa, yayin da matsayin ƙimar karfi yake ƙaruwa, danko ya ragu. Ana kiran wannan halin "Shear Thinning" ko "Shenning" kuma yana da matukar mahimmanci a aikace-aikace da yawa masu amfani. Misali, a cikin filayen mayafin, shirye-shiryen abinci, sarrafa abinci, halayyar cututtukan ƙwayoyin cuta na HPMC na iya tabbatar da cewa ana ci gaba da danko mai sauƙi a cikin yanayin sauri mai sauri.
4. Sauran dalilan suna shafar danko na maganin hpmc ruwa
(1) sakamakon gishiri
Bugu da kari na gishiri (kamar sodium chloride) na iya ƙara danko na maganin hpmc ruwa mai ruwa. Wannan saboda gishirin ne saboda gishiri na iya haɓaka hulɗa tsakanin kwayoyin ta hanyar canza ƙarfin ionic ƙarfi don samar da tsari na cibiyar sadarwa, don haka ƙara danko. Koyaya, tasirin nau'in gishiri da maida hankali kan danko kuma yana buƙatar gyara daidai gwargwadon takamaiman yanayi.
(2) tasirin wasu karin ƙari
Dingara wasu ƙari (kamar Surfactants, polymers, da sauransu) zuwa maganin ruwa mai ruwa na HPMC zai kuma iya shafar danko. Misali, Surfactants na iya rage danko na HPMC, musamman lokacin da Surfactant ke da yawa. Bugu da kari, wasu polymers ko barbashi na iya yin hulɗa tare da HPMC kuma suna canza kaddarorin kayan maganin ta.
Halayen danko namethypyl methylcelose Abubuwan da aka fi dacewa da abubuwan da yawa, gami da maida hankali, zazzabi, darajar ph, yana da kyawawan abubuwan kaddarorin, kuma suna da kyau a cikin filayen masana'antu da magunguna masu yawa da magunguna masu kyau. Fahimtar da masu jan hankali da wadannan halayen kayan kwalliya zasu taimaka inganta amfani da HPMC a cikin aikace-aikace daban-daban. A cikin aikace-aikacen aikace-aikace, ya kamata a zaɓi nau'in HPMC da ta dace da yanayin aiwatar da takamaiman buƙatun don samun ingantaccen danko da na rhiyerian kaddarorin.
Lokacin Post: Mar-01-2025