HPMC (Hydroxypropyl Methylcellulose) wani fili ne mai narkewa da ruwa wanda ake amfani da shi sosai a cikin magunguna, abinci, gini, kayan kwalliya da sauran masana'antu. HPMC wani sinadari ne na cellulose na roba wanda aka samu ta hanyar gyare-gyaren sinadarai na cellulose na halitta, kuma yawanci ana amfani dashi azaman thickener, stabilizer, emulsifier da m.
Kaddarorin jiki na HPMC
Matsayin narkewa na HPMC ya fi rikitarwa saboda yanayin narkewar sa ba a bayyane yake ba kamar na kayan kristal na yau da kullun. Matsayinsa na narkewa yana shafar tsarin kwayoyin halitta, nauyin kwayoyin halitta da digiri na maye gurbin hydroxypropyl da kungiyoyin methyl, don haka zai iya bambanta bisa ga takamaiman samfurin HPMC. Gabaɗaya, a matsayin polymer mai narkewar ruwa, HPMC ba ta da madaidaicin wuri mai narkewa kuma iri ɗaya, amma yana tausasa kuma yana ruɓe a cikin takamaiman yanayin zafi.
Kewayon ma'anar narkewa
Halin yanayin zafi na AnxinCel®HPMC ya fi rikitarwa, kuma yawanci ana nazarin halayen ruɗuwar zafinsa ta hanyar nazarin thermogravimetric (TGA). Daga wallafe-wallafen, ana iya gano cewa kewayon yanayin narkewa na HPMC yana kusan tsakanin 200°C da 300°C, amma wannan kewayon baya wakiltar ainihin wurin narkewa na duk samfuran HPMC. Daban-daban na samfuran HPMC na iya samun maki narke daban-daban da kwanciyar hankali na thermal saboda dalilai kamar nauyin kwayoyin halitta, digiri na ethoxylation (digiri na maye gurbin), digiri na hydroxypropylation (digiri na maye gurbin).
Ƙananan nauyin kwayoyin HPMC: Yawancin lokaci yana narkewa ko yin laushi a ƙananan yanayin zafi, kuma yana iya fara pyrolyze ko narke a kusan 200°C.
Babban nauyin kwayoyin halitta HPMC: HPMC polymers tare da mafi girman nauyin kwayoyin halitta na iya buƙatar yanayin zafi mafi girma don narke ko laushi saboda tsayin sassan kwayoyin halitta, kuma yawanci suna fara pyrolyze da narke tsakanin 250°C da 300°C.
Abubuwan da ke tasiri wurin narkewar HPMC
Nauyin kwayoyin halitta: Nauyin kwayoyin halitta na HPMC yana da tasiri mafi girma akan wurin narkewa. Ƙananan nauyin kwayoyin halitta yawanci yana nufin ƙananan zafin jiki na narkewa, yayin da babban nauyin kwayoyin zai iya haifar da matsayi mafi girma.
Matsayin maye: Matsayin hydroxypropylation (watau maye gurbin hydroxypropyl a cikin kwayoyin halitta) da digiri na methylation (watau canjin rabo na methyl a cikin kwayar halitta) na HPMC shima yana shafar wurin narkewa. Gabaɗaya, babban digiri na maye yana ƙara haɓakar HPMC kuma yana rage maƙasudin narkewa.
Abubuwan da ke ciki: A matsayin abu mai narkewar ruwa, wurin narkewa na HPMC shima yana shafar damshin sa. HPMC tare da babban abun ciki na danshi na iya sha ruwa ko narkar da wani sashi, yana haifar da canji a cikin yanayin bazuwar thermal.
Thermal kwanciyar hankali da bazuwar zafin jiki na HPMC
Ko da yake HPMC ba shi da matsananciyar narkewa, kwanciyar hankali ta thermal shine maɓalli mai nuna alamar aiki. Dangane da bayanan bincike na thermogravimetric (TGA), HPMC yawanci yakan fara bazuwa a cikin kewayon zafin jiki na 250.°C zuwa 300°C. Ƙayyadadden zafin jiki na bazuwar ya dogara da nauyin kwayoyin halitta, digiri na maye gurbin da sauran kayan jiki da sinadarai na HPMC.
Jiyya na thermal a aikace-aikacen HPMC
A cikin aikace-aikace, wurin narkewa da kwanciyar hankali na thermal na HPMC suna da mahimmanci. Misali, a cikin masana'antar harhada magunguna, ana amfani da HPMC sau da yawa azaman abu don capsules, suturar fim, da masu ɗaukar magunguna don ci gaba da sakin magunguna. A cikin waɗannan aikace-aikacen, kwanciyar hankali na thermal na HPMC yana buƙatar saduwa da buƙatun zafin aiki, don haka fahimtar yanayin zafi da kewayon narkewar HPMC yana da mahimmanci don sarrafa tsarin samarwa.
A cikin filin gine-gine, AnxinCel®HPMC ana yawan amfani dashi azaman mai kauri a busasshiyar turmi, sutura da adhesives. A cikin waɗannan aikace-aikacen, kwanciyar hankali na thermal na HPMC shima yana buƙatar kasancewa cikin takamaiman kewayon don tabbatar da cewa baya rubewa yayin gini.
HPMC, a matsayin kayan aiki na polymer, ba shi da ƙayyadadden ma'anar narkewa, amma yana nuna alamun laushi da pyrolysis a cikin wani yanayin zafi. Matsayinsa na narkewa gabaɗaya yana tsakanin 200°C da 300°C, kuma takamaiman wurin narkewa ya dogara da dalilai kamar nauyin kwayoyin halitta, digiri na hydroxypropylation, digiri na methylation, da danshi abun ciki na HPMC. A cikin yanayin aikace-aikacen daban-daban, fahimtar waɗannan kaddarorin thermal yana da mahimmanci don shiri da amfani.
Lokacin aikawa: Janairu-04-2025