Tsarin fim shine tsari mai mahimmanci a cikin masana'antar magunguna, a cikin magudanar bakin ciki ana amfani da polymer a farfajiya na allunan ko capsules. Wannan kayan aikin yana ba da dalilai da yawa, gami da inganta bayyanar, dandana maskarewa, yana kare ƙwararrun Sinadaran (API), suna sarrafawa, da kuma sauƙaƙe haɗiye. Hydroxypyl methyplulose (hpmc) shine ɗayan mafi yawan polymers da aka fi amfani da su a cikin fim ɗin da ta fi ƙarfinsa.
1.Prockerties na HPMC:
Hydroxypyl methypcellulose (hpmc) polymer semi-rentmer ne wanda aka samo daga cellulose. An san shi da ruwa-karancin ruwa, ikon samar da fim, da kyau sosai tare da kayan cinikin harhada magunguna daban-daban. Za'a iya dacewa da kadarorin HPMC ta hanyar gyara sigogi kamar nauyi na kwayoyin, matsayin canji, da danko, da danko.
Fim yana haifar da iyawa: HPMC tana da ingantattun kayan fim-forming, suna ba da damar samuwar uniform da santsi shafi a saman siffofin ɓangaren magunguna.
Sanarwar ruwa: HPMC ta nuna karancin ruwa, bada izinin rushe polymer a cikin hanyoyin ruwa a lokacin aiwatar da shafi. Wannan dukiyar tana tabbatar da rarraba kayan polymer kuma yana sauƙaƙe ƙirƙirar tsarin haɗin kai.
M: HPMC tana nuna kyakkyawar m adheshima zuwa saman allunan ko capsules, sakamakon coxed coxs da mawuyacin gashi.
Abubuwan da Balaguru: HPMC ta samar da wani shamaki kan dalilai na muhalli kamar danshi, oxygen, da haske, game da amincin tsari da haɓaka kwanciyar hankali da inganta kwanciyar hankali.
Adadin shawara:
A cikin ƙirƙirar bayani mai fim ɗin ta amfani da HPMC, da yawa dalilai suna buƙatar la'akari da halaye da aikin da ake so.
A hankali polymer: maida hankali kan HPMC a cikin shafi bayani yana da kauri da kayan aikin injin na fim. Mafi girman maida hankali polymer yana haifar da kayan kwalliyar kauri tare da kayan shafewar.
Filastik na filastik: Bugu da kari na filastik kamar polyethylene glycol (Peg) ko propylene glycol (pg) na iya inganta sassauci da elarguity na shafi, sanya shi ƙasa da ɓarke, sa shi ƙasa da fashewa da mafi tsayayya ga fatattaka.
Hanyoyi: Zabi na kananan abubuwan da suka dace yana da matukar muhimmanci don tabbatar da maganin hpmc da ingantaccen fim ɗin da ya dace. Hanyoyin gama gari sun haɗa da ruwa, ethanol, isoproropannol, kuma ga gaurayan sa.
Pigments da OPAfiers: haɗa da launuka da opacifiers cikin tsarin haɗin kai na iya hana launi, inganta bayyanar, kuma samar da kariya, da samar da haske kwayoyi.
3.Apliction na HPMC a cikin fim ɗin fim:
HPMC-tushen sutturori yana samuwa aikace-aikace masu yawa a masana'antu masu samar da kayayyaki saboda abubuwan da suka shafi su da dacewa don siffofin sashi daban-daban.
Za'a iya amfani da mayafin da nan da nan: ana iya amfani da riguna na HPMC don samar da kwayoyi ta hanyar sarrafa abubuwan rarrabewa da kuma rushewar allunan alluna ko capsules.
A canza sakin suttura: An saba aiki da tsarin HPMC da aka saba aiki a cikin nau'ikan sakin sakin sakin, gami da tsawaita da tsarin da aka tsara. Ta hanyar gyaran danko da kauri daga cikin shafi, bayanan saki na miyagun miyagun ƙwayoyi za a iya dacewa su samu ci gaba ko saki.
Ku ɗanɗani masking: mayafin hpmc na iya maskar da dandano mai daɗi na kwayoyi, inganta yarda da haƙuri da yarda da kayan ado na baka.
Kariyar danshi: HPMC Coatings suna ba da kariya ta danshi kariya, musamman ga hygroscopic kwayoyi da ke haifar da lalata saboda bayyanar da danshi ga danshi.
Ingancin kwanciyar hankali: HPMC Saterings samar da shinge na kariya daga dalilan muhalli, ta hanyar inganta kwanciyar hankali da tanad-rayuwar kayayyakin magunguna.
Hydroxypyl methypze (HPMC) ya taka rawa sosai a aikace-aikacen shafi na fim a cikin masana'antar harhada magunguna. Abubuwan da ke Musamman na musamman, har da ikon samar da fim, mai ƙila, m, da katako mai kyau, sanya shi zabi mafi kyau don tabbatar da kayan kwalliya tare da mahimmancin aiki. Ta wurin fahimtar la'akari da aikace-aikacen HPMC a cikin kayan aikin fim, masu samar da magunguna na iya haɓaka siffofin kayan kwalliya tare da haɓaka haɓaka, kwanciyar hankali, da kuma rashin haƙuri.
Lokaci: Mar-07-2024