ʻO nā leka uila e pili ana i ka home a ma waho o ka hoʻomākaukauʻana i nā hoʻomākaukauʻana o ka lāʻau lapaʻau nā noi ma ke kula o nāʻano hou o nāʻano hou e like me nāʻano hana a me nā biodhestives. Ma muli o kaʻokoʻa ma ka moloki wahapiha poʻo poʻo poʻo nui a me ka viscosity o HPMC, ua loaʻa kaʻike,ʻano, ho'ūmiʻana, i ka piʻiʻana, ke kīʻana a me nā kiʻi. Ua hoʻohana nuiʻia ia ma nā hoʻomākaukauʻana o Pharmaceutical a e pāʻani i kahi hana nui ma ke kula o ka hoʻomākaukau. Me ka aʻoʻana o ka hohonu o kona mau waiwai a me ka hoʻomaikaʻiʻana i kaʻenehanaʻoihana,ʻo HPMC e hoʻohana nuiʻia i ka noiʻiʻana o nā'ōnaehana.
hydrexxypopypoprowlse; pharnauceical hoʻomākaukau; ʻO nā mea maikaʻi o nā mea kūʻai aku.
ʻAʻole wale ke kumu o nā mea kūʻai aku i ke kumu no ka hoʻokumuʻana o ka hoʻomākaukauʻana o ka lāʻau, akā e pili ana i ka hoʻoikaika Nā hana hana a me nā ala hou o nā alakaʻi. pili pili. ʻO ka wā e hiki mai ana o nā mea hoihoi hou e hoʻomaikaʻi pinepineʻia i ka hoʻomaikaʻiʻana i ka maikaʻi o ka hoʻomākaukauʻana a me ke kūkuluʻana i nā palapala hana hou. ʻO ka hydroxyproopsl methylcelllulose (hpmc) kekahi o nā mea momona maikaʻi loa i ka home a ma waho. Ma muli o kona mau kūlana nohoʻokoʻa a me ka makaʻala, he kuleana ia o ka paulsivoining, paleʻia, a hoʻomake, a ho'ōho, a ho'ōki, a me ka hōʻiliʻiliʻana, a me ka'ōmaʻomaʻo. Nā hiʻohiʻona a me nā hoʻohana e like me ka coagulation a me keʻano kiʻi kiʻi i hoʻohana nuiʻia ma kaʻenehanaʻo Parrmaceuture. Hōʻike nuiʻia kēiaʻatikala i ka noiʻana o ka noiʻana o HydroxyPyl Midylcellse (HPMC) i nā hana i nā makahiki i hala.
1.Nā waiwai maʻamau o HPMC
ʻO Hydroxyproopplayl Millll Celluluse (HPMC),ʻo ka'ōlelo moleleʻo C8h15- o ka cellouse. Hiki ke hanaʻia ma nā alaʻelua:ʻo kekahi i hanaʻiaʻo Mathyl Cellow i kahi papa kūpono ma lalo o ka mahopa Pono ka lōʻihi o ka manawa e hiki ai i ka lōʻihi o kaʻaeʻana a me ka hydroxyproopsl e hana i nā mea e pili ana i keʻano o ka cellupuse ʻO ka mea'ē aʻe e mālama i ka cotton linter a iʻole ka lāʻau lāʻau lāʻau me ka couustic soda, a laila e hana hou i ka clornicated , uaʻokiʻia i loko o nā mea momona maikaʻi a me ke kapa paha.
Ua keʻokeʻo ke keʻokeʻo o kēia huahana i ka waiū keʻokeʻo, a me ka momona a me kaʻonoʻole, a me keʻano maʻalahi a iʻole keʻano he nui. Hiki ke hoʻopauʻia kēia huahana i ka wai e hana ai i kahi mālamalama keʻokeʻo i loko o ka solloidal keʻokeʻo keʻokeʻo me kahi viscosity. Hiki i ka Pūnaewele Interconvernivers Col-Gel i hiki ke hele ma muli o keʻano o ka hoʻololiʻana o ka hopena o ka hopena me kahiʻike.
Ma muli o kaʻokoʻa i loko o nā manaʻo o kēia mau mea i loaʻa i keʻano o ka methoxy a me hydroyprostl, nāʻanoʻano likeʻole. I nāʻike kiko'ī, nāʻano huahana likeʻole o nā huahana kūikawā. No lailaʻo Viscosity a me keʻano o keʻano o keʻano o ka Thermal Glation, no laila he mau mea likeʻole a hiki ke hoʻohanaʻia no nā kumu likeʻole. ʻOkoʻa nāʻano likeʻole o nā'āina'ē aʻe a me nā'ōlelo e pili ana i nā kumu hoʻohālike o nā huahana ". Ma ka US Pharmacopooeia, 4 mau helu helu ma hope o ka inoa inoa e hōʻike ai i nāʻike a me keʻano o kēlā me kēia helu he hydronchelsell ʻO ka pakeneka,ʻo nā helu hopeʻelua i hōʻike i ka pakeneka ma keʻano he nui o ka hydroxyproopsl.
Loaʻa iā CardCAxyParproploSl i keʻano he 3 papa inoa,ʻo ia ka Series,ʻo K Series,ʻo kēlā me kēiaʻano likeʻole o nā hiʻohiʻona e koho ai mai. Hoʻohana nuiʻia nā papa hana e like me nā kiʻiʻoniʻoni kiʻi, hoʻohanaʻia no ka papaʻaina papa, paniʻia nā papa papa papa; E, hoʻohanaʻia nā hana FORS e like me nā viscosifiers a hoʻokuʻu i nā mea kūʻai aku no Ophthalmic Ua hoʻohana nuiʻiaʻo K SCOUS e like me ka hoʻokuʻuʻana i nā mea hoʻonāukiuki a me ka hydrophilic gel matrix no nā hoʻomākaukauʻana a me ka hoʻokuʻuʻana i ka hoʻokuʻuʻana i ka lohi.
Wahi a nā mea hana hale hana i ka fuzhou nor 2 cheents, hubeian ginlical bhance, hulina luzounchenical ah, ., Ltd., xiʻan remical good chemari, etc.
2.Loaʻa iā HPMC
Ua liloʻo HPMC i kekahi o nā mea maikaʻi loa i hoʻohana nuiʻia ma ka home a me waho, no ka mea, he mea pono nā HPMC i nā mea hoihoi.
2.1ʻO ka wai wai anuanu
Lulu i loko o ka wai anuanu ma lalo o 40 ℃ a 70% ethanol, nā mea momona loa ma luna o ka wai wela ma luna o 60 ℃, akā hiki iā Gel.
2.2 i loko
ʻO HPMC kahiʻano o nā meaʻole o ke keleponaʻole,ʻaʻole i loaʻa i kāna mau mea a me keʻano o nā mea hoʻonaninani a me nā mea'ē aʻe i hanaʻia me ke kaʻina hana o ka hanaʻana.
2.3 Kahi paʻa
He paʻa kūpono ia i ka acidʻelua a me Alkali, a hiki ke mālamaʻia no ka lōʻihi ma waena o PH 3 a 11 me ka loli nui o ke kolo. ʻO ka hopena a me ka hopena o HPMC kahi hopena anti-mildew a mālama i ka hoʻomau maikaʻi o ka viscosity maikaʻi i ka wā hoʻomaha lōʻihi. ʻO nā mea nui o nā mea hoihoi e hoʻohana ana i ka HPMCʻoi aku ka maikaʻi o ka HPMC ma mua o ka hoʻohanaʻana i nā mea ola maʻamau (e like me DXTRIN, ATC.).
2.4ʻO ka hoʻoponoponoʻana o Viscosity
Hiki ke hoʻohuiʻia nā loea viscosity likeʻole o HPMC i nāʻano likeʻole, a loaʻa hoʻi i keʻano laina, no laila e kohoʻia ka hoʻolālā e like me nā pono.
2.5 metabolical interness
ʻAʻole i hoʻopiliʻiaʻo HPMC a iʻole metabilinized i ke kino,ʻaʻole e hāʻawi i ka wela, no laila he mea hoʻomaʻamaʻa palekana palekana palekana palekana. 2.6ʻO ka palekana i manaʻoʻiaʻo ia ka mea maʻamauʻo HPMC i kahi meaʻoleʻole a me ka nui o nā mea make me nā mea make me nā mona no nā miss he 5. 2 G · 2 G · 2 G · (. ʻAʻole maikaʻi ka hana o kēlā me kēia lā i ke kino o ke kanaka.
3.ʻO ka noiʻana o HPMC i nā hana
3.1 Ma keʻano o nā kiʻiʻoniʻoni kiʻiʻoniʻoni a me nā kiʻi kiʻi kiʻi kiʻi
Ke hoʻohana nei i ka HPMC e like me kahi papa hana papa kiʻi kiʻi kiʻiʻia,ʻaʻole pono ka papa hana i hoʻopaʻaʻia e like me nā papaʻaina ciated. ,ʻoi aku ka maikaʻi o ka loaʻaʻana o ka momona momona a me nā hōʻailona'ē aʻe. Hoʻohanaʻia ka papa haʻahaʻa haʻahaʻa o kēia huahana ma keʻano he mea kāwili wai waiʻole ka wai no nā papa hana a me nā pukipaʻa moʻukioʻana ma keʻano he helu hoʻopaʻa manuahi. %.
Zhang jixing et al. Ua hoʻohana i ka hana kūpono e hoʻopili ai i ka hana premix me ka hpmc e like me ka papa kiʻi kiʻiʻoniʻoni. Ke lawe nei i nā kiʻi kiʻi kiʻi kiʻi kiʻi-form, ka nui o ka pôpeku a me nā mea waiwai a me ka hōʻikeʻana o ke kiʻiʻoniʻoni a me ka pilina ma waena o ke nānāʻana Ua weheweheʻia nā kuhikuhi a me nā mea nānāʻole e kahi kumu hoʻohālikelike, a ua loaʻa hope ka hopena o ke kaʻina hana kūpono. ʻO kona hoʻohanaʻana he kiʻi kiʻi kiʻi kiʻi kiʻiʻiaʻo iaʻo GreylChelbalse (HPMCU5) . ^. Ua hoʻomaikaʻiʻo Zhangʻo Yhaan i ke kaʻina hoʻomākaukau, i hoʻohanaʻiaʻo HPMC e like me ka papa hana o nā hale kūʻai i hanaʻia, e hoʻomaikaʻi i nā papaʻainaʻo Jiata, hoʻonui i ka paʻaʻana o ka papa. Ua hoʻoholoʻia ke kaʻina hana kūpono e nā hoʻokolohua Orthogonal,ʻo ia hoʻi,ʻo ia ka hopena o ka Slurry i ka makahiki 7 i ka makahiki 15 min. Nā hopena i hoʻomākaukauʻia ai nā papa kiʻi kiʻiʻoniʻoni kahiko e ke kaʻina hana hou a me ka paʻakikī o ka hana mua a me ka nui o nā papa hana likeʻole a me ka helu o nā papa hana me mua a me ka helu o ka papa hana manuahi a me ka helu o nā papa hana manuahi a me ka ukuʻana o nā papa hana mana a me ke kumukūʻai o Picture ua loaʻa ma mua o 95%. Liaose Meiyi, lu Xiaoshi, etc. i hoʻohana i ka mana o ka paila Kolo mateinae e hoʻomākaukau ai i ka papaʻaina pili i ka hoʻokuʻu lāʻau. Huang Yunran i hoʻomākaukauʻia nā papa koko koko, a hoʻopiliʻiaʻo HPMC i ka hopena o ka papaʻaina, aʻo kāna mau'āpana nui loa he 5%. Hiki keʻikeʻia e hiki ke hoʻohana nuiʻiaʻo HPMC i ka'ōnaehana hāʻawi kālā i kohoʻia.
ʻAʻole waleʻo Hydroxyproopylflorlose i kahi kiʻiʻoniʻoni maikaʻi loa, akā hiki ke hoʻohanaʻia e like me keʻano kiʻiʻoniʻoni Wang TomShun Etc. Ua kohoʻia i ka papa inoa o ka compid zinc a me ka maʻalahi E hoʻokōʻo Popslene Glycol i nā koi o ka wikiwiki a me ka palekana, a hiki ke hoʻohanaʻia e like me keʻano o ka hoʻomaʻamaʻa hoʻonohonohoʻana.
3.2 e like me ka pale a me ka mea hanaʻole
Hiki ke hoʻohanaʻia ka papa kiʻekiʻe o kēia huahana o kēia huahana e like me kahi mea paʻa a me ka meaʻole i ka papa, nā papa kiʻekiʻe, a me nā granusisty Hoʻololi ka Dosage me nā hiʻohiʻona likeʻole a me nā koi. ʻO ka maʻamau,ʻo ka dosage o ka paleʻana no nā papaʻaina maloʻo he 5%, a me ka dosage o nā papa papa o nā papa papa he 2%.
ʻO Li Houtao et al screted i ka paleʻana o nā papa tindazole. ʻO 8% PolyvinYlPyRoSone (PVP-K30), 40% Sturor, 2%ʻO GRANSHCYLL) ka hoʻomākaukauʻana i nā papa tnidazale. ʻO ka'ikeʻana o nā papaʻainaʻulaʻula a ma hope o ka hoʻohālikelikeʻia, a me ka maʻi hopohopo, ka paʻakikī o ka heluʻana o nā papa no nā kaʻina hana likeʻole a me ka neʻe palena o nā papa mua. ʻO nā hopena i mākaukau e ka papaʻaina ma ka 2.0%ʻO ka hoʻopaʻaʻanaʻo LongyLChelose, a me ka uhiʻana, a maikaʻi hoʻi ka papaʻaina. No laila, i hoʻomākaukauʻia nā papa Tnidazal me 2.0% HPMC-K4 a me 50% ethanol e like me nā mea i hoʻohanaʻia. Ua aʻoʻiaʻo Guan Shi Hoa , 5% cmc-na a 15% hpmc sult (5 mpa s). Nā hopena i hoʻomākaukauʻia e 50% ethanol, 15% mau pā'ālua a me nā mea he 5% o ka maninol. 15% hpmc hopena (5 mpa · nā) Nolaila, ua kohoia ka HPMC (5 MPA S) e like me ka adhesive.
3.3 E like me ka mea i hoʻopaʻaʻia
Hoʻohanaʻia ka papa kiʻekiʻe o kēia huahana ma kahi huahana e like me ka mea e hoʻopiʻi nei e hoʻomākaukau i ka hoʻomākaukauʻana i ka subpension-type wai. He hopena paʻakikī maikaʻi loa, he mea maʻalahi ke maʻalahi i ka reisterperse, mai lāʻau i ka paia, a loaʻa i nā'āpana flcculation maikaʻi. ʻO ka Dosage maʻamau he 0.5% i 1.5%. Mele tian et al. Ua hoʻohana pinepineʻia nā hana Polymer i nā hana Polymer lohi maloʻo. Ma o ke kahe kuʻina o ka sedimentation of likeʻole, nā mea hoʻihoʻi hou, a me keʻano o ka moʻa i nānāʻia a me ka microscopic. Nā hualoaʻa i hoʻomākaukauʻia i ka maloʻo maloʻo me 2% HPMC e like me ka mea i hoʻokuʻuʻia i keʻano maʻalahi a me ka kūpaʻa maikaʻi.
Hoʻohālikelike me nā mana momi,ʻo ka hydroxyproopsl milllulse e loaʻa ana i nāʻano meaʻole e hiki ai ke loaʻa i kahi mea kūʻai aku. Liu jie et al. Ua hoʻohana iā HPMC, hydroxyproopsl celpulse (hpc), carborer 940 kohoʻiaʻo ia e like me nā hōʻailona loiloi e pale ai i ka paleʻana i ka mea hoʻokele maikaʻi loa. Hōʻike ka hopena i ka hoʻoneʻeʻana o ka pōʻaianuiʻo Ahulāʻau, he maikaʻiʻo ka hapa o ka radio.
3.4 Ma keʻano he blocker, lohi a mālama i ka hoʻokuʻuʻana i ka hoʻokele a me ka hoʻokele
Hoʻohanaʻia ka papa kiʻekiʻe o ka huahana o kēia huahana no ka hoʻomākaukauʻana i ka papaʻaina hydrophilic, hoʻokuʻu i nā papaʻaina He 10% o ka huiʻana he 10% a 80%. Hoʻohanaʻia nā helu haʻahaʻa haʻahaʻa e like me nā perogens no ka hoʻokuʻuʻana a iʻole nā hoʻomākaukauʻana i hoʻokuʻuʻia. ʻO ka hana mua i koiʻia no ka hopena o ka mokuahi o kēlā mau papa, hiki koke ke hoʻokuʻuʻia ka hopena o ke kino manuahi i loko o ke kino. . ^. ʻO ka hydroxyprooppopplayl ʻO keʻano o ka hōʻikeʻana o ka lāʻau lapaʻau mai ka papa matrix e pili nui ana i keʻano o ka'āpana o ka gel o ka gel i ke aniani. Jung b bo shim et al i hoʻomākaukau i nā papa i hoʻomākaukauʻia i nā papa i hoʻokuʻuʻia me ka hpmc e like me nā mea i hoʻokuʻuʻia.
Hoʻohana nuiʻia nā mea i hoʻohanaʻiaʻo HydroxyLRellosel Liu wen et al. Ua hoʻohanaʻia 15% hydroxxyll mathylcelunuse e like me kaʻenehana matrix, 1% mau lālāʻo Microfrystalse Clingqi i nā papaʻaina. ʻO ke kumu hoʻohālike ka hoʻohālikelikeʻana o ka Higuchi. Hoʻololi maʻalahi ka'ōnaehana hoʻohui no ka hoʻomākaukauʻana, he maʻalahi ka hoʻomākaukau, a he paʻa nā loiloi, e hui ana i nā koi o ka Kinakuaki. Tang guanguang et al. Hoʻohanaʻia nā soponaniona piha o assrapalus e like me ka lāʻau lapaʻau e like me nā hua lāʻau lapaʻauʻo HPMC i nā papa lāʻau lapaʻau ma Hpmc martice. E hopena e like me ka hoʻonuiʻana o ka dosoage o Hpmm i hoʻonui, i ka hoʻokuʻuʻana o Astragalo e pili ana i ka hana o ka lāʻau lapaʻau. Ma ka Hypomalse HPMCTux papa pākuʻi, aia kekahi pilina ma waena o ka hoʻokuʻuʻana o ka lāʻau lapaʻau maʻamauʻo ka naloʻo Lord. ʻAʻole kūpono waleʻo Hydroxyprooparpopulose Liu Guihua i hoʻohanaʻia 17% hydroxyprooparlulose (hpmck15m (HPMCK15M Ua maopopo ka hopena o ka hoʻokuʻu i ka hopena, a ua paʻa ka hana hoʻomākaukau a hiki ke loaʻa.
ʻAʻole hoʻohanaʻiaʻo Hydroxyprooparpoparlose i nā papa hana mate-hoʻokuʻu i nā papa hana ikaika a me nā mea maikaʻi o ka lāʻau lapaʻau maʻamau. Wau huiio et al. Ua hoʻohanaʻia 20% hydroxxyprockl millluluse (HPMck4m) e like me ka papa hana kūpono e hoʻomākaukau ai a kū paha i ka lāʻau. Soponin RG1, Ginsenmies Rb1 a me Panax Notinseng Saponnin R1 i hoʻohanaʻia e aʻo i ka hōʻike loiloi i ka hanaʻana i ka mīkini hana loiloi. Nā hopena i nā mea i hoʻokuʻuʻia i ka mīkini i hoʻokuʻuʻia i ka hoʻohālikelikeʻana o ke kauoha a me ka hoʻohālikelikeʻia e nā mea.
3.5 pale i ka glue e like me ka skickener a me ka colloid
Ke hoʻohanaʻia nei kēia huahana e like me ka shaickener,ʻo keʻano maʻamau maʻamau he 0.45% i 1.0%. Hiki iā ia ke hoʻonui i ke kūpaʻa o ka gluedophobic glue, e pale i kahi colloid colloid, pale i nā'āpana mai ke kauʻana i keʻano o nā sediment. ʻO konaʻano maʻamau maʻamau he 0.5% i 1.5%.
Wang Zhen et al. Ua hoʻohana i ka L9 Orthogonal hoʻokolohua hoʻolālā hoʻolālā e noiʻi i ka hana hoʻomākaukau e hana ai i ka lāʻau lapaʻau. ʻO nā kūlana hana kūpono loa no ka hoʻoholo hopeʻana i ka lāʻau lapaʻau e hana ai i ka carboxyl cellhexyl ʻO ka paʻaʻana o ka lāʻau lapaʻau i hana i ka carbon. Zhang zhiqiang et al. Kūkuluʻia kahi leka uilaʻo PH ʻO ka hana mua ma ka hoʻokolohuaʻana, e loaʻa ana ka hope o ka predrogen hydrochurlose ,,03 G o ka Sotyl Paraben, a hoʻohuiʻia ka wai e hana i 100 ml. I ka hōʻikeʻana, ua paʻi ka mea kākau i kaʻenehana hydrocelsel malp. ʻO ka Swickener no ka PH-Sensitive Leafloxacin hydrochloride gelts gelts.
3.6 e like me nā mea capsule
ʻO ka maʻamau,ʻo ka mea hana pale capsule o nā capsules ka gelatin nui. ʻO ke kaʻina hana o ka pahu kaloli he maʻalahi ia, akā aia kekahi mau pilikia a me nā phenomeka e pale aku i ka hoʻoheheʻeʻana i ka paluhiʻana i ka wai haki. No laila, hoʻohanaʻia ka hyderoxsprocklulose i ka kohoʻana no nā pōpoki hoʻonāukiuki no ka hoʻolauleʻaʻana i nā lāʻau lāʻau lāʻau, a ua hoʻomaikaʻi nuiʻia ma ka hale mālama formanc no me ka pono.
Ka hoʻohanaʻana iā Theophylline e like me ka lāʻau lapaʻau e kāohi ana, podczeck et al. uaʻikeʻia e loaʻa ana ka nui o ka lāʻau lapaʻau o nā capsules me nā'āpanaʻo hydroxyproopulose ʻO ke kumu no ka loiloiʻanaʻo ia ka weheʻana o ka HPMC ka mea i hoʻokaʻawaleʻia i ka manawa holoʻokoʻa, a laila ka weheʻana o ka pā o kaʻoihana. ʻOi aku ka maikaʻi o HPMC COPULE no nā mea kūʻai aku no ka hoʻokuʻu kokeʻana i nāʻano hana. Chiwele et al. Loaʻa nō hoʻi i nā hopena like like a hoʻohālikelike i ka neʻeʻana o Gelatin, Gelatin / Poyethylene Glycol a me nā HPMC Ua hōʻikeʻo nā hopena i nā mea i hikiʻole ke hoʻopauʻia nā mea hou o HPMC ma lalo o nā kūlana ph,ʻoiaiʻo Gelatin Copules e hoʻopilikia nuiʻia e nā kumu ph. Tang yue et al. slick i kahiʻano o ka pūpū capsule no ka mīkini haʻahaʻa haʻahaʻa haʻahaʻa haʻahaʻa e pale ai i ka'ōnaehana pale. Hoʻohālikelike me ka Kāpili Kālea o K hydroxxyprockl mathylcelulse a me nā wahi o ka pōpoki,ʻo keʻano o ka palekopa, a ua hoʻokōʻia nā huahana o ka pōkole, a ua hoʻokōʻia ka pono o ka pōpoki. Hōʻike nā hopena i ka mea i hoʻohālikelikeʻia me nā capsules glatin,ʻoi aku ka maikaʻi o nā mea nānā aku, a me nā pale o nā cops i loko o nā capsule
3.7 Ma keʻano he bioadhetive
Hoʻohana kaʻenehana biodheson i nā mea hoihoi i nā mea hoihoi me nā polymers bidadhes. Ma ka hoʻolahaʻana i ka muchical muchical musosa, e hoʻonui i ka hoʻomau a me ka paʻa o ka hoʻopiliʻana a me nā mea i hoʻokuʻuʻia e ka mucosa e hoʻokō ai i ke kumu o ka mālamaʻana. Ua hoʻohana nuiʻia ma kēia manawa. ʻO ka mālamaʻana i nā maʻi o ka gestrointestinal stact, vagina, waha mucosa a me nā'āpana'ē aʻe.
ʻO Gastrointestinal Biodhesion Technology he mea kūʻai aku i ka'ōnaehana lawe kālā hou i kūkuluʻia i nā makahiki i hala. ʻAʻole ia wale nō ka manaʻo o ka manawa noho o ka lāʻau lapaʻau i ka papa hana gastrointestinal, akā e hoʻomaikaʻi i ka hana ma waena o ka lāʻau lapaʻau ma waena o ka lāʻau lapaʻau Hoʻopiliʻia nā cells deterstinal liʻiliʻi, me ka hoʻihoʻiʻana i ka BALIANALABISTIBISTIBlility o ka lāʻau lapaʻau. Wei Keda et Al. Ua paʻiʻia i ka papa kuhikuhi papa inoa me ka dosage o HPMCK4M a me Carbomer 940 e like me keʻano o ka nui o ka wai i loko o ka pahu pahu. , a i hope ua koho i nāʻike o HPMK40 a me Carbora 940 a me 27.5 mg ma nā mea koho balota o Ncadebt ʻO ka'ōmole o ka hoʻomākaukauʻana i ka kiko.
ʻO nā hoʻomākaukauʻana o nā hana Biodothesiveʻo ia kahiʻano hou o ka'ōnaehana laweʻana i nā'ōnaehana i hoʻopaʻaʻia i nā makahiki i hala iho nei. Hiki i nā mākaukau o nā hana Biodothesive e pili ana i ka lāʻau lapaʻau i ka'āpana o ka lua ʻOi aku ka maikaʻi o ka hana kolohe a hoʻomaikaʻi i ka lāʻau lapaʻau lāʻau lapaʻau. Xue xiaoyan et al al. Hoʻolilo i keʻano o ka insulin o nā papa lāʻau insulin i nā papaʻaina o ka'ōpū, e hoʻohana ana iā Apple Pectin, a me ke kalaʻana e hoʻomākaukau ai i nā mea biodhesLulose (hpmc ʻO ka pepa papa pālua pālua. ʻO ka papa lāʻau insulin i hoʻomākaukauʻia i ka papa hana pôpeku maikaʻiʻole e like me keʻano o ka hanaʻana, a he mea hiki ke hōʻoia i ka hāʻuleʻana o ka lāʻau lapaʻau. HAOW JUFU et al. Māmā pū kekahi i nā poloka polū polū polū polū me ka hoʻohanaʻana i ka gaiji glue, HPMC a me Carbomer A me nā mea biomadiative.
I nā'ōnaehana o nā'ōnaehana o ka lāʻau lapaʻau, ua hoʻohana nuiʻia kaʻenehana biodheson. Zhu yuting et al. Ua hoʻohanaʻo Carbomer (CP) a me HPMC e like me nā mea hoʻonaninani a me nā mea i hoʻoponoponoʻia e nā clorinterazle biodothes i keʻano o nā clotriclival , ua paʻiʻia ka papa kuhikuhi ma keʻano he cp-hpmc1: 1, he mea maʻalahi ka hana aʻoi aku ka maikaʻi o ka hanaʻana, a ua maʻalahi a hiki i ke kaʻina.
3.8 e like me ke aloha topical
Me he hoʻomākaukau hoʻomākaukauʻana, he gel he mau hana e like me ka palekana, nani, hoʻomaʻemaʻe maʻalahi, a me nā hana kūpono loa. Kuhikuhi o ka hoʻomohalaʻana. ʻO ka laʻana,ʻo ka gel reserdermal heʻano hana hou i aʻoʻia ma nā makahiki i hala iho nei. ʻAʻole hiki iā ia ke pale aku i ka lukuʻana o nā lāʻau lapaʻau i loko o ka pā o Gastrointestinal a hōʻemi i ka'ōnaehana o ka lāʻau lapaʻau e lanakila ai i nā hopena lāʻau lapaʻau e lanakila ai i nā hopena lāʻau lapaʻau kūpono. . ^.
Zhu jingjie et al. E aʻo i ka hopena o nāʻano likeʻole ma ka hoʻokuʻuʻana i ka gel prittiplan e like me ka celdolcellose (380nf15m Geltatrix o nā plastids pream. Hōʻike nā hopena hoʻokolohua i hōʻikeʻia 1. 0% Carbomer, 1. . ^. I ka wā hoʻokolohua, uaʻikeʻiaʻo ka HPMC ke hoʻololi i kaʻano kaila o Carbomer a me 1.5% Carbomer Matrix. ʻO ke kumu paha e hoʻonui wikiwiki aiʻo HPMC, a me ka hoʻonui houʻana i ka hana mua o ka hoʻokolohua Zhaoi wennicui et al. Ua hoʻohanaʻo Carbor-934 a me HydroxyPyl Midylcellse e like me Carriers e hoʻomākaukau iā Norfloxic Gel. He maʻalahi a maʻalahi ke kaʻina o ka hoʻomākaukauʻana, a me ka hopena maikaʻi loa i ka Ophthammic Gel o "Chine Parmacomoeia" (2010 edition) nā pono kūpono.
3.9ʻO ka inoibith inhibitor no ka'ōnaehana micromullitying pono'ī
ʻO ka micromuloki houʻana i nā'ōnaehana hana lapaʻau (SDDD) heʻano hana hou o ka mea kūʻai aku He maʻalahi keʻano o ka hoʻonohonohoʻana o ka papa kuhikuhi, a he maikaʻi ka palekana a me ke kūpaʻa. No nā lāʻau lapaʻau maikaʻiʻole, nā wai wai-sollast fiber potmer hoʻonui i ka mea lapaʻau lāʻau lapaʻau a hoʻomaikaʻi i ka biovailability.
Peng xuan et al. Mākaukau i kahi Silibninin Supernitrated Silibniturated-Emulsitying System Drive System (s-sedds). ʻO ka Oxyitlylene Holdrogonated Hydrogeated Keokeo (Cremophor RH40), 12% CAPRYFELL GLYTYYYYNET E hoʻohui i ka HPMC e hiki i nā SSEDD e hiki i SUSRESATURATE FREE Silibninin e wehe i ka S-SEDD a e pale i SiliBInin mai ka wā i hala. Hoʻohālikelikeʻia me nā moʻomeheu pilikino pilikino pono'ī,ʻo ka nui o nā mea nui e hoʻohui pinepineʻia e paleʻia ai nā lāʻau lapaʻau o ka lāʻau lapaʻau. Hiki i ka hoʻohui o HPMC hiki ke mālama i ka hopena o Silbibinin ma ka weheʻana o ka neʻeʻana i ka umu pono'īʻana iāʻoe iho. dosage o ka luna.
4.ConClision
Hiki keʻikeʻia e hoʻohana nuiʻiaʻo HPMC i nā hoʻomākaukau ma muli o kona mau mea kino, he nui nā mea hana a me ka hpmc. Methyl Methacrylat) e hoʻomaikaʻi. I ka manawa like, ua noi kekahi poʻe noiʻi i ka noiʻana o Osmotic i nā papa hana surbamazel i ka papaʻana i ka hanaʻana i nā papa hana Ma kahi hua'ōlelo,ʻoi aku ka nui a me nā mea noiʻi hou aku no ka hana maikaʻi loa o HPMC, a me ka hoʻomaikaʻiʻana i nāʻano hana hou a me nā puka dosage hou. I ka noiʻiʻana o ka'ōnaehana lāʻau lapaʻau, a laila e hoʻolaha i ka hoʻomohala mauʻana o ka lāʻau lapaʻau.
POST manawa: Oct-08-2022