ʻO ka hopena o ka Hydroxyproopsl

Hydrexypropropsl hydrolcellse (HPMC) he mea maʻamau maʻamau i hoʻohanaʻia ai ka wai wai, hoʻohana nuiʻia ma nā lāʻau lapaʻau, nā mea kanu, meaʻai a me nāʻoihana a me nāʻoihana a me nāʻoihanaʻoihana a me nāʻoihanaʻoihana ʻO kāna mau hiʻohiʻona pilikino a me nāʻano hana kūpono i loaʻa i kahi hopena koʻikoʻi ma ka hopena o nā noi likeʻole. ʻO ke aniani Gelution o Hpmc Gel keʻano pilikino, kahi e pili pololei ana i kāna hana ma nāʻano like, e like me ka hōʻike, kamaʻilio, mecec.

1. Kūkulu a me nā waiwai o HPMC

ʻO Hpmc kahi mea i hoʻohuiʻia ai ka wai i loaʻa ma o nā mea heʻelua,ʻo hydshypopypopyl a me ka mathyl, i loko o ka myyll ʻO kānaʻano molecular e loaʻa ana iʻelua mauʻano o nā mea i koiʻia: hydroyprooppyl (-ch2chohch3) ʻO nā mea e like me nā mea e like me nā mea e hydroxyprooppyl

I nā hopena kūponoʻole, ke hopohopo nei i nā hopena collidal stable ma keʻano he nui o nā mydrogen me nā moloki wai. Ke hoʻololi nei kaʻenehana o waho

2.ʻO ka wehewehe a me nā mea e hoʻoulu ai i nā mea o ka mahana o ke kaʻa

Hoʻomaka ka mahana o keʻano (ʻo ka mahana o keʻano, t_gel) i ka mahana e hoʻomaka ai ka hopena o ka hpmc i kahi o ka ea e kū ai i kahi pae. Ma kēiaʻano inoa, e kaupakuʻia ka neʻeʻana o HPMC MOOLELO

ʻO ka mahana o ka gelation o ka HPMC e pili ana i nā kumu he nui Ma kahi o nā mea e pili ana i ka hydroxyproopsl

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3.1ʻO ka hoʻonuiʻana i nā mea e hele ai i ka hydroxyproopsl e alakaʻi i kahi hoʻonui i ka mahana o Gel

ʻO ka mahana o keʻano o ka hpmc e pili kokoke ana i ke kiʻekiʻe o keʻano hydroxyprockl boddroxyprockl ma kona molena. Ke hoʻonui nei kaʻike o ka hydroxyproopspoppppppppppppppopyl, ka nui o nā costitunic constituc ma luna o ka molmc molecular ʻO kēia ka manaʻo e hoʻokumu i nā kaulahao molela e hoʻohiki hou,ʻo ka hoʻemiʻana i ka ikaika o ka pilina ma waena o nā kaulahao molecular. I loko o kahiʻano haʻahaʻa o keʻano, e hoʻonui ana i kaʻike hydroxxypopyl e hoʻomaikaʻi i ka hoʻopaʻaʻana o nā molokiʻana, no laila hiki i ka hoʻonohonohoʻana ke kuʻiʻia i kahi kūlana kiʻekiʻe. No laila, hoʻonui pinepine ka mahana koʻikoʻi me ka hydroxyprooppyl e piʻi ana me ka hoʻonuiʻana i nāʻike.

Hpmc me nā mea kiʻekiʻe hydroxyproopsl (e like me hpmc k15m) e hōʻike i kahi kiʻekiʻe o ka hydrocled kiʻekiʻe (e like me hpmc k4m). ʻO kēia no ka meaʻoi aku ka paʻakikī o ka hydroxxypopyal . ^.

3.2ʻO ka pilina ma waena o ka hydroxyprooppyl a me ka hoʻokōʻana

ʻO keʻano o ka noʻonoʻoʻana he kumu koʻikoʻi ka mea nui e pili ana i ka mahana o ka gelation of hpmc. I loko o nā hopena hiʻona HPMC kiʻekiʻe, he mea ikaika ka piliʻana o nā intermolecular Ma ka haʻahaʻa haʻahaʻa, palupalu ka launa ma waena o Hpmc Molecules, aʻoi aku ka hopena o ka hopena i ka nui o ka kiʻekiʻe.

Ke hoʻonui nei kaʻike o ka hydroxyprooppppppppppppppppppppppppppppoppropy,ʻoiai ka hoʻonuiʻia o ka hydrophilicity, e koiʻia kahi kiʻekiʻe kiʻekiʻe e hana i kahi gel. ʻOi aku ma lalo o nā kūlana haʻahaʻa haʻahaʻa, e hoʻonui nui keʻano o keʻano o keʻano. ʻO kēia no ka meaʻo HPMC me nā mea kiʻekiʻe hydroxyprooppyl eʻoi aku ka paʻakikī o ka hoʻopiliʻana i nā kaulahao ma waena o ka mahana o keʻano he nui o keʻano o ka wela.

3.3ʻO ka hopena o keʻano o ka hydroxyproopsl ma ke kaʻina hana

I loko o kahiʻano o nā mea e pili ana i ka hydroxyproopsl I ka wā iʻikeʻia ai kaʻike hydrocyprooppsl i ka HPMC MOLECULE, nāwaliwali o ka hydration, e hoʻomaikaʻi i keʻano o nā molecules, Ke kiʻekiʻe aʻe kaʻike o ka hydrosybopypopyl, ua hoʻonuiʻia ka hydration, e hoʻonui ka launa ma waena o nā kaula molele, a hoʻonui ka heleʻana o ka mahana o ka molela.

Hiki ke alakaʻiʻia kaʻike hydroxyprockLl

Loaʻa iā HydroxyPropsl i kahi hopena koʻikoʻi nui i ka mahana o keʻano o kaHpmc. ^. Ke hoʻonui nei kaʻike o ka hydroxyproopspoppppppppppppppppopyl, ka hydrophinicity o HPMC a me ka hoʻopiliʻana ma waena o nā pale molena, no laila e hoʻonui ka nui o keʻano o keʻano o nā molekini Hiki ke weheweheʻia kēia phenonie i keʻano o ka intracantis i waena o ka hydration a me nā kaulahao mole. Ma ka hoʻoponoponoʻana i kaʻikepili hydroxyprooppyl o HPMC, hiki ke hoʻokōʻia ka mana o ka gelation, e kali ana i ka hana o ka hpmc i ka lāʻau lapaʻau.