Mokuna: Nā mea hana; Menmrane mea like; ʻO nā mea i hoʻokaʻawaleʻia i nā meaʻo Polymer Ho'ākāka i ka luna; Hoʻolilo kōkua kōkua, e kau ana i ka papa; Hoʻoikaika hou i nā mea hoʻokele.
1. Ka hoʻomaikaʻi huahana
ʻO kēia huahana he mea'oleʻo keʻano o ke aniani,ʻaʻole i nānā i ka pauʻole o ka wai, a me kaʻeha o ka wai. ʻO ka hopena o ka aqueous ka hana i ka hana,ʻoi aku ke kiʻekiʻe o keʻano a me ka hana paʻa. Ua loaʻa iā HPMC i ka waiwai o ka gel wela. Ma hope o ka hoʻomoʻaʻana, ka hopena o ka huahana aceuous ka huahana gel i ka pauʻana, a laila haʻalele i hope o ka hoʻomahaʻana. ʻOkoʻa keʻano o keʻano o nā kiko'ī likeʻole. ʻO nā loli loli me ka viscosity, he haole Zhao, ka nui o ka palaualelo, nāʻokoʻa likeʻole o ka wai.
Ka mahana o ke aniani, wehe i ka momona,ʻoiaʻiʻo a me ke aniani o ke aniani a me ke aniani. Ma hope o ka hoʻomoeʻana, huli ia i ka brown i ka makahiki 190 ~ 200 ° C a me ke ahi ma 225 ~ 230 ° C.
Ua kokoke loaʻo Hpmc i CHLOROCHICH, eThanol (95%), a me ka huiʻana o ka wai a me ka huiʻana o ka wai a me'Ethylene keʻa a me'Eliolol. Hoʻokomoʻia kekahi mau pae o hpmc i ka mahele o ka lehulehu,ʻo ka huiʻana o ka mloride, a me 2 e pili ana i nā mea kūʻai aku no nā organik.
Papa 1: Nā leka uila
Kumu
Kahakai,
60 GD (2910).
65gd (2906)
75gd (2208)
Methoxy%
28.0-32.0
27.0-30.0
19.0-24.0
Hydroxyproopory%
7.0-12.0
4.0-7.5
4.0-12.0
Ke ana aniani.
56-64.
62.0-68.0
70.0 2.90.0
Viscosity mpa s.
3,5,6,15,50,4000
50400 0
100400 0150 00100 000
ʻO ka maloʻo maloʻo%
5.0 a iʻole a iʻole
Kuni ahi%
1.5 a emi mai paha
pH
4.0-8.0
Means MaSped
20 a iʻole ka liʻiliʻi
arsenic
2.0 a emi mai paha
2. Nā hiʻohiʻona huahana
2.1ʻO ka hydroxyproopyll methylcrelllulose i hoʻopauʻia i ka wai anuanu e hana i kahi hopena colcous colcous colcoudal. E like me ka wā e hoʻohuiʻia ai i ka wai anuanu a liʻiliʻi iki, hiki ke hoʻopauʻia i loko o kahi hopena transparent. Ma ke kū'ē, he insolully maʻamau i loko o ka wai wela ma luna o 60 ℃ a hiki ke hele wale. I ka hoʻomākaukauʻana o ka hydroxyproopsl minicellose etqurious sult,ʻoi aku ka maikaʻi o ka wai hydrofyprolol i ka nui e pono ai.
2.2ʻO ka Ethinixloplosel Methistlcelllose he meaʻole-Ionic cell cell hua.
2.3ʻO ka hydroxyproopsl mathylcelllose he anti-mody, a me ka piʻiʻana o keʻano o keʻano molena, ua hoʻonuiʻia ka anti-consittivity. ʻO nā lāʻau lapaʻau e hoʻohana ana i ka HPMC e like me ka maikaʻi o nā mea hoihoi i loko o ka manawa kūpono ma mua o nā lāʻau lapaʻau e hoʻohana ana i nā lāʻau lapaʻau'ē aʻe (startrin
2.4ʻO ka metabolilpoplosel metaboliclolose ka metartlcelloully. E like me keʻano o ka lāʻau lapaʻau,ʻaʻole ia he metabolilized a iʻole a hoʻopiliʻia, no lailaʻaʻole ia e hāʻawi i ka wela i nā lāʻau a me nā meaʻai. He mea hoʻohana ponoʻole i ka waiwai haʻahaʻa haʻahaʻa, ka paʻakai, nā lāʻau lapaʻauʻole,ʻaʻohe meaʻai a me nā meaʻai no nā maʻi maʻi.
2.5hpmc maʻamau e paʻa mau ana i nā acids a me nā waihona, akā ināʻoi aku ka nui o ka ph i ka manawa kiʻekiʻe, e hōʻemi i ke kiʻekiʻe o ka nui.
2.6ʻO ka hopenaʻo Hydroxyprooparplayl Midylcelllose e hiki ai i ka hoʻonāʻana ke hana i ka hana ma ka hana, e hōʻike ana i nā pono kūpono a me nāʻano kūlike a me keʻano o nā mea hoʻonaninani. He mea kūpono ia e kau nei i ka'ōnaehanaʻelua a hiki ke hoʻohanaʻia e like me kahi stabilizer kūpono a pale aku i ka colloid.
2.7ʻO HydroxyPropsl Metresslcelllose Aqueuous sultemings he waiwai maikaʻi loa, aʻo ia kahi mea hana maikaʻi maikaʻi no nā papa a me nā pā. ʻO ka membrane i hoʻokumuʻia e ia he kala a paʻakikī. Inā hoʻohuiʻiaʻo Glyceol, hiki ke hoʻonuiʻia kona poʻe palela. Ma hope o ka mālamaʻana, ua hoʻoneʻeʻia ka huahana ma ka wai anuanu, a hiki ke kāohiʻia ka pae dissolution e hoʻololi i ke kahua. Hoʻohanaʻia ia ma ka hoʻomākaukauʻana i ka lohi a me ka hoʻomākaukauʻana i nā koho.
3.
3.1. Ua hoʻohanaʻia e like me ka adhesteive a me ka hoʻokaʻawaleʻana
Hoʻohanaʻiaʻo HPMC e hoʻolauleʻa ai i ka hana o ka lāʻau a me ke kiʻekiʻe o nā noi i hoʻokuʻuʻia, hiki ke hoʻokaʻawaleʻia i ka hpmc ʻO Agent, a me ka viscosity kiʻekiʻe no ka glue, hoʻohana wale nō i ka loaʻaʻana o nāʻano likeʻole a me nā koi likeʻole, he 2% o ka laulā.
Hpmc aqueous sult a me kekahi mea e pili ana i ka ethanol e hana i kahi mea hoʻohui; Hōʻikeʻia: 2% HPMC AQUISUS i huiʻia me 55% o Ethanol i hoʻohanaʻia no ka papa inoa amoxichin
Hiki ke hanaʻiaʻo HPMC i ka hoʻopiliʻana i ka hoʻohuiʻana me nāʻano likeʻole o ka starch slurry ma hope o kaʻaeʻana; Ua hoʻonuiʻia ka weheʻana o nā papa inoa o ErythromyCin i nā papa inoa inoaʻo ErythromyCin i kohoʻia mai 38.26% a 97.38% i ka wā 2% a me ka 2%.
2.2. E hana i nā kiʻiʻoniʻoni kiʻiʻoniʻoni a me nā kiʻi kiʻi kiʻi
Hpmc e like me keʻano o ka wai wai-wai i lalo o nā hiʻohiʻona e pili ana i nā hiʻohiʻona He maʻalahi keʻano uila; ʻO ka kiʻi maikaʻi e hana ai i ka waiwai; Hiki ke mālama i keʻano o ka'āpana, ke kākau nei; Hiki ke lilo i monstureprofof; Hiki ke kala, hoʻoponopono i ka flavor. Hoʻohanaʻia kēia huahana e like me ka waihī wai wai-wai wai no nā papaʻaina a me nā pakani kiʻiʻoniʻoni, a no ka nui o keʻano
2.3, ma keʻano he mea kākau moʻolelo a me nā colloidal palekana
Ua hoʻohanaʻo HPMC e like me ka Agent Thickening Agent he 0.45% ~ 1.0%, hiki ke hoʻohanaʻia e like me keʻano o ka maka Hoʻohana e hoʻonui i ka kūpaʻa o ka hydrophobic gluece, pale i ka paleʻana, ua pau, he 0.5% ~ 1.5%.
2.4, e like me ka blocker, e hoʻokuʻu i nā mea e hoʻokuʻu i ka mea hoʻokele
Hoʻohanaʻiaʻo Hpmc High Viscosity Modehity Modehing e hoʻomākaukau i nā blockers a me nā hoʻokele e hoʻokuʻu i nā mea i kāwiliʻiaʻo ka mīkini. ʻO ka hiʻohiʻona haʻahaʻa haʻahaʻa haʻahaʻa loa ia i ka luna
2.5. Gel a me ka wahine a me ke kumu
ʻO Hydrogel Sposposies a me nā hoʻomākaukauʻana o Geastric e hoʻomākaukauʻia e ka hoʻohanaʻana i keʻano o keʻano o ka hana hydrogel i hoʻohana pinepineʻia e ka hpmc i ka wai.
2.6 Nā Kūlana Kūʻai Kūlana
Hui pūʻiaʻo matrontazole me HPMC a me PYCSCHBEXYYTLENLYLYLYLYLYLYLYLYLYLYLYLY FIIPETED E hana i nā papa i hoʻopaʻaʻia i 250MG. I ka ho'āʻoʻana i ka hoʻokolohua Vitro Hōʻoia nei ua neʻe wikiwiki ka hoʻomākaukauʻana i loko o ka wai, a me ka hoʻokuʻuʻana o ka lāʻau lapaʻau ma ka hoʻomahaʻana i ka lewa. Hōʻike ka hana holoholona holoholona i nā'ōnaehana wikiwiki hou i loaʻa i nā waiwai a nā biological nui e pili ana i ka mucosition
2.7, e like me ke kōkua kōkua
ʻO ke kula kiʻekiʻe o kēia huahana he kōkua kōkua maikaʻi loa no ka hoʻopauʻana i ka hoʻomākaukauʻana i ka wai,ʻo ka dosage maʻamau he 0.5% ~ 1.5%.
4. Nā hiʻohiʻona noi
4.1 Nā 'Cooklelo Cotpenelepa: HPMC, HPMC, THE TICC 2Ka Galymen. ʻElua mau ala e hana ai.
4.1.1 hoʻomākaukauʻana i nā lole i hoʻopaʻaʻia i nā wai . ^. Hoʻohui i 80% o ka hopena (20% no ka polish) me ka helu o ka aila o ka maura, he'umikūnē-kālā.
4.1.2 E hoʻomākaukau ana i nā puaʻa insollable (e like me ka hao o ka waiū) e like me ka pō. Ua laweʻia 20% o kēia hoʻonā no ka polish, a ua hoʻomākaukauʻia ke koena o ka 80% e ka nui o nā wahi e ae a me ka hoʻohanaʻana i nā mea'ē aʻe no ka hoʻohanaʻana. ʻO ke kaʻina hana o ke kāʻei o ka coating: E ninini i ka pepa palaoa i loko o ke kō, ma hope o ka neʻeʻana i ka wela, e hoʻomau ana Me ka ea wela no 5 ~ 10min hiki i waho o ka ipuhao, e hoʻokomo i ka mīkini maloʻo e maloʻo ai ma mua o 8h.
4.26 Hanaʻia kēia huahana i loko o nā kiʻiʻoniʻoni.
4.3ʻO CTTIMIMIXZALL E kāwili i ka SMZ a me TMP, a laila e hoʻohui i ka Starch a hui pū no 5Min. Me ka Prefabricated 3% HPMC AQUISE GOLDS, TRUMPY FREATER, MATH CREET BRANDE MA AGH SCRANDE MA AGH Screen Hoʻohana nuiʻia kēia huahana ma keʻano he meaʻole. ʻO ka weheʻana o nā papaʻainaʻo 96% / 20MIN.
4.4 Pīpepapapa (0.25G) Pīpeke 80 Mesh 25KG ʻO kānaʻano hua hana e pili ana i ka pika opala, frirch gurn, me 20% a me 20m turn ) nā papaʻaina. Me ka starch e like me ka hoʻokaʻawaleʻana o ka mea hoʻokele,ʻaʻole i emi iho ka helu dissolution o kēia papaʻaina ma mua o 80% / 2min,ʻoi aku ka kiʻekiʻe o nā huahana ma Iapana.
4.5 Ka Mokuahi HPMC-4000, HPMC-4500 a iʻole HPMC-5000 BORUCH ʻO kānaʻano hana hanaʻo HPMC i waihoʻia ma ka wai 15ML, ma ka 80 ~ 90 ℃ piha i ke koena o ka nui o ka nui, a laila hoʻohuiʻia ke wai , Hoʻopili pinepineʻia i ka filtration, e kiʻi i loko o ka ipu i hoʻopaʻaʻia, sterlilized at 98 ~ 100 ° C. I ka manawa i hoʻohanaʻia no ka microscopy anterior ma keʻano kūpono, hiki ke hoʻonui kūpono i ka dosage o kēia huahana, 0.7% (1.5% kūpono.
4.6ʻO Mitthorphan i hoʻopaʻaʻia e hoʻokuʻu i ka papaʻo Cetthorphan Reset Salt 180mg Silita, PVECHC, PVECHC, PVECYSTALLS CILLUE 2.5MGY CHITEATETER CILLUE 2.5MG. Mākaukau ia e like me nā papa ma keʻano maʻamau. Hoʻohanaʻia kēia huahana e like me ka hoʻokuʻuʻana i nā mea i hoʻokuʻuʻia.
4.7 No nā mea kūʻai aku nei, a me nā papaʻaina, 2149G avantomycin ⅳ monohydrat a me 1000: a maloʻo loa, a maloʻo loa, a maloʻo hoʻi Ua hoʻohuiʻiaʻo ka nui o nā runu a me 675g a me 62.5g hydroxyproopyloulse e-502 a laila e kiʻiʻia ana i nā papa ma Vanguard. Hoʻohanaʻia kēia huahana e like me keʻano wikiwiki.
4.8ʻO nā nifedicine Sulnus ʻano. ʻAʻole i piliʻia ka nui o ka wikiwiki o nā granules o nā granules e ka loli o ka loli o ka honua Ma hope o 12 mau hola o ka hoʻokele waha,ʻo ke kahe koko o ke koko he 12mg / ml, aʻaʻohe mea'ē aʻe.
4.9 Proprahaol hydrochwalroide e hoʻokuʻu i nā copsule propranhaol hydrochlorlos 60kg, microcrystallise cellulose 40kg, e hoʻohui i nā wai 50l e hana i nā granules. Ua huiʻiaʻo HPMC1kg a me EC 9kg i ka Sluted Scored Kāwili i nā'āpana āpau o mM, a laila ua piha i loko o ka kāpau pōhaku me ka mīkini hoʻopihapiha. Aia i kēlā me kēia capsule i 160mg o nā propranollol hydrochloride spherical spherical spherical.
4.10 Nā Peprool HCColeton Nā Papa'āina MCColeton ma Mākaukauʻia ma ka Hoʻohuiʻana iā Naprooll HCRO: HPMC: CMC-NA I ka RMC-na ma ka ratio: HPMC: 0.25: 2.25. Ua kokoke kokoke ka helu o ka lāʻau i ke kauoha e pili ana i ke kauoha o Zero i loko o 12 mau hola.
Hiki i nā lāʻau lapaʻau'ē aʻe ke hanaʻia i nā mea i kāwiliʻiaʻia e like me Metoprolol: HPMC: CMC-NAM: 1.25: 1.25: 1.25: 1.25: 1.25: 1.25: 1.25: 1.25: 1.25: 1.25: 1.25: 1.25 AllylProlol: HPMC E like me ka 1: 2.8: 2.9-ratio. Ua kokoke kokoke ka helu o ka lāʻau i ke kauoha e pili ana i ke kauoha o Zero i loko o 12 mau hola.
4.11 Skeleton nā papa hana o nā mea i hoʻohuiʻia i nā kumuwaiwai o Estylamilosine Hiki ke hoʻokuʻuʻia ka lāʻau lapaʻau no 12h iʻelua ma Vitro a ma Vivo, aʻo ka Linor E hoʻokuʻu i keʻano maikaʻi. ʻO nā hopena o ka hōʻoiaʻana o ke kūpaʻa paʻa e like me ka FDA REGLANS E wānana i ke ola o kēia huahana a hiki i nā makahiki 2 a hiki i nā makahiki 2.
4.12 HPMC (50mpa · s) (5 mau'āpana) maloʻo maloʻo. Loaʻa i kēia huahana ka 80% o ka lāʻau lapaʻau nui.
4.13 Ua heluʻiaʻo Therophylline Hydropphilic Gel skeleton e like me ke kaumaha nui, 18% -22.5% ka nui Mālama i keʻano koko olakino o ke kino o ke kino no 12h ma hope o ka hoʻokele waha.
Post Time: Feb-05-2024