He aha ka helu heheʻe o HPMC polymer?

HPMC (Hydroxypropyl Methylcellulose) he mea hoʻohui wai-soluble polymer i hoʻohana nui ʻia i ka lāʻau lapaʻau, ka meaʻai, ke kūkulu ʻana, nā mea hoʻonaninani a me nā ʻoihana ʻē aʻe. ʻO ka HPMC he semi-synthetic cellulose derivative i loaʻa ma ka hoʻololi kemika o ka cellulose maoli, a hoʻohana mau ʻia e like me ka mānoanoa, stabilizer, emulsifier a me ka hoʻopili.

Nā waiwai kino o HPMC

ʻOi aku ka paʻakikī o ka helu heheʻe o HPMC no ka mea ʻaʻole i ʻike ʻia kona helu heheʻe e like me nā mea crystalline maʻamau. Hoʻopili ʻia kona wahi hoʻoheheʻe e ka molecular structure, molecular weight a me ke degere o ka hoʻololi ʻana o nā hui hydroxypropyl a me methyl, no laila hiki ke hoʻololi e like me ka huahana HPMC kikoʻī. ʻO ka mea maʻamau, ma ke ʻano he polymer hiki ke hoʻoheheʻe ʻia i ka wai, ʻaʻohe HPMC i kahi helu heheʻe a kūlike, akā palupalu a decomposes i loko o kahi pae wela.

Laulā helu heheʻe

ʻOi aku ka paʻakikī o ka hana wela o AnxinCel®HPMC, a ke aʻo pinepine ʻia kona ʻano decomposition wela e ka thermogravimetric analysis (TGA). Mai ka palapala, hiki ke ʻike ʻia ʻo ka helu heheʻe o HPMC ma waena o 200°C a me 300°C, akā ʻaʻole hōʻike kēia pae i ka helu heheʻe maoli o nā huahana HPMC āpau. Hiki i nā ʻano like ʻole o nā huahana HPMC ke loaʻa nā helu heheʻe a me ke kūpaʻa wela ma muli o nā kumu e like me ke kaumaha molekala, degere o ka ethoxylation (degree of substitution), degere o ka hydroxypropylation (degree of substitution).

Haʻahaʻa molekala kaumaha HPMC: He mea maʻamau a palupalu paha i ka haʻahaʻa wela, a hiki ke hoʻomaka i ka pyrolyze a heheʻe paha ma kahi o 200°C.

ʻO ke kaumaha molekala kiʻekiʻe HPMC: ʻO nā polymers HPMC me ke kaumaha molekala kiʻekiʻe ke koi aku i nā mahana kiʻekiʻe e hoʻoheheʻe a palupalu paha ma muli o ko lākou mau kaulahao molekala lōʻihi, a hoʻomaka pinepine e pyrolyze a heheʻe ma waena o 250°C a me 300°C.

Nā mea e pili ana i ka helu heheʻe o HPMC

Kaumaha Molekala: ʻOi aku ka hopena o ke kaumaha molekala o HPMC i kona wahi heheʻe. ʻO ke kaumaha molekala haʻahaʻa, ʻo ia hoʻi, ʻoi aku ka haʻahaʻa o ka wela hoʻoheheʻe ʻana, aʻo ke kaumaha molekala kiʻekiʻe ke alakaʻi i kahi helu heheʻe kiʻekiʻe.

Degere o ka hoʻololi: ʻO ke degere o ka hydroxypropylation (ʻo ia hoʻi ka lākiō hoʻololi o ka hydroxypropyl i loko o ka mole) a me ke degere o ka methylation (ʻo ia hoʻi ka lākiō hoʻololi o ka methyl i loko o ka mole) o HPMC pū kekahi i kona wahi heheʻe. ʻO ka mea maʻamau, ʻoi aku ka kiʻekiʻe o ka hoʻololi ʻana i ka solubility o HPMC a hoʻemi i kona helu heheʻe.

ʻAno wai: Ma ke ʻano he mea hiki ke hoʻoheheʻe ʻia i ka wai, pili pū ka helu hoʻoheheʻe o HPMC i kona ʻano wai. Hiki i ka HPMC me ka mākū kiʻekiʻe ke komo i ka hydration a i ʻole ka hoʻoheheʻe hapa, e hopena i ka hoʻololi ʻana i ka mahana decomposition thermal.

Paʻa wela a me ka wela decomposition o HPMC

ʻOiai ʻaʻohe wahi hoʻoheheʻe koʻikoʻi o ka HPMC, ʻo kona kūpaʻa wela he hōʻailona hana nui. Wahi a ka ʻikepili thermogravimetric (TGA), hoʻomaka maʻamau ka HPMC e decompose i ka pae wela o 250°C a hiki i 300°C. ʻO ka mahana decomposition kikoʻī e pili ana i ke kaumaha molekala, degere o ka hoʻololi ʻana a me nā waiwai kino a me nā mea kemika o HPMC.

Lapaʻau wela ma nā polokalamu HPMC

I nā noi, he mea nui ka helu heheʻe a me ka paʻa wela o HPMC. No ka laʻana, ma ka ʻoihana lāʻau lapaʻau, hoʻohana pinepine ʻia ʻo HPMC ma ke ʻano he mea no nā capsules, nā uhi kiʻiʻoniʻoni, a me nā mea lawe no nā lāʻau hoʻokuʻu mau. I loko o kēia mau noi, pono e hoʻokō ka paʻa wela o ka HPMC i nā koi wela o ka hoʻoponopono ʻana, no laila ʻo ka hoʻomaopopo ʻana i ka ʻano wela a me ka helu heheʻe o HPMC he mea koʻikoʻi i ka mālama ʻana i ke kaʻina hana.

Ma ke kahua kūkulu, hoʻohana pinepine ʻia ʻo AnxinCel®HPMC ma ke ʻano he mānoanoa i ka mortar maloʻo, nā uhi a me nā mea hoʻopili. I loko o kēia mau noi, pono nō hoʻi ka paʻa wela o ka HPMC i loko o kahi kikoʻī e hōʻoia ai ʻaʻole ia e decompose i ka wā o ke kūkulu ʻana.

HPMC, ma ke ʻano he mea polymer, ʻaʻohe wahi hoʻoheheʻe paʻa, akā hōʻike i nā hiʻohiʻona palupalu a me ka pyrolysis i loko o kahi pae wela. Aia ma waena o 200 kona pae hehee°C a me 300°C, a me ka helu heheʻe kiko'ī ma luna o nā mea e like me ke kaumaha molekalaleo, degere o hydroxypropylation, degere o ka methylation, a me ka moisture maʻiʻo o HPMC. Ma nā hiʻohiʻona noiʻi like ʻole, ʻo ka hoʻomaopopo ʻana i kēia mau mea wela he mea koʻikoʻi no ka hoʻomākaukau ʻana a me ka hoʻohana ʻana.