Daim ntawv thov HPMC hauv kev lag luam hauv kws tshuaj

HydroxyPropyyl methylcellulose (HPMC), tseem hu ua Hypromellose, yog siv dav hauv kev lag luam kws tshuaj vim nws cov khoom muaj ntau yam. Nov yog qee cov kev siv ntawm HPMC hauv cov chaw muag tshuaj:

1. Ntsiav tshuaj: HPMC feem ntau yog siv cov phau ntawv sau ua qauv rau imfart cohesiveness thiab txhim kho cov ntsiav tshuaj hardness. Nws pab tuav cov hmoov hmoov ua ke ua ke thaum muaj kev sib xyaw, ua rau cov ntsiav tshuaj nrog kev sib xyaw thiab lub zog kho tshuab.
2. Zaj duab xis txheej tus neeg sawv cev: HPMC yog siv los ua zaj duab xis-txheej tus neeg sawv cev los muab cov tshuaj tiv thaiv thiab / lossis tshuaj pleev ib ce. Cov yeeb yaj kiab txheej txhim kho cov tsos, saj ntsej muag, thiab muaj kev ruaj khov ntawm lub chaw tshuaj tshuaj paus tshuaj. Ib qho ntxiv, nws tuaj yeem tswj cov tshuaj tawm suab, tiv thaiv cov tshuaj los ntawm ya raws, thiab pab txhawb kev nqos dawb.
3. Matrix yav tas los: HPMC yog siv los ua ib qho matrix yav dhau los hauv kev tswj hwm-tso tawm thiab raug tshem tawm cov ntsiav tshuaj tsim qauv. Nws tsim cov gel txheej rau ntawm cov dej cawv, uas tswj cov kev sib txawv ntawm cov tshuaj los ntawm kev siv tshuaj ntau npaum li cas, ua rau cov nyhuv prolonged.
4. Kev ua txhaum: Hauv qee cov qauv, HPMC tuaj yeem ua raws li kev ua tsis taus, txhawb nqa cov ntsiav tshuaj lossis cov tsiav tshuaj lossis cov tshuaj ntsiav rau hauv lub plab zom mov. Qhov kev ua yeeb yam no ua rau muaj kev sib cais thiab kev nqus, kom ntseeg tau zoo tshaj plaws cov me me.
5. Viscosity Monifier: HPMC yog siv los ua viscosity concifiter hauv cov kua thiab semi-storulation formulations suav xws li kev ncua, emulsions, thiab tshuaj pleev, thiab tshuaj pleev. Nws muab kev tswj rawv, txhim kho qhov ruaj khov ntawm kev ncua, thiab txhim kho kev tawm tsam thiab cov khoom sib xyaw ua ke.
6. Stabilizer thiab emulsifier: HPMC yog siv los ua cov stabilizer thiab emulsifier hauv cov kua sib cais, txhim kho homogeneity ntawm cov khoom. Nws yog feem ntau siv nyob rau hauv qhov ncauj hais, phoovs, thiab emulsions.
7. Tus neeg saib xyuas tuab: HPMC tab tom siv los ua tus neeg sawv cev tuab ntawm ntau cov tshuaj kom nce viscosity thiab muab cov khoom siv uas xav tau. Nws txhim kho cov qauv thiab xwm yeem ntawm cov ntsiab lus npaj xws li cream, pelsions, thiab cov kua pleev, txhim kho lawv cov tawv nqaij thiab tawv nqaij.
8. Opaceifier: HPMC tuaj yeem siv los ua tus neeg sawv cev opacifying hauv qee cov qauv los cuam tshuam txog kev tswj hwm lossis kev tswj hwm opacity. Cov cuab yeej no yog pab tau tshwj xeeb rau hauv ophthalmic formulations, qhov twg opacity tuaj yeem txhim kho qhov pom kev ntawm cov khoom thaum lub sijhawm tswj hwm.
9. Lub tsheb rau cov tshuaj siv tshuaj: HPMC yog siv los ua lub tsheb lossis tsheb thauj khoom hauv cov tshuaj siv tshuaj xws li microspheres, nanoparticles, thiab hydrogels. Nws tuaj yeem encapsatate tshuaj encapsatate, tswj cov tshuaj tso tawm kinetics, thiab txhim kho cov tshuaj ruaj khov, muab cov hom phiaj thiab tswj tau cov tshuaj.

HPMC yog ib qho kev zam tau zoo rau cov tshuaj, suav nrog cov ntsiav tshuaj sib dhos, ua kom muaj kev sib cais, opacification, thiab kev xa khoom siv tshuaj. Nws siv ua rau muaj kev txhawb nqa kev nyab xeeb, ua tau zoo, thiab tus neeg mob-tus neeg ua lag luam tshuaj.