Hydroxypropylencellulose (HPMC) yog cov dej-soluble polymer dav siv nyob rau hauv ntau yam kev lag luam xws li tshuaj, zaub mov pleev, thiab kev tsim kho. HPMC paub txog nws cov khoom siv dej zoo heev, ua rau nws muaj cov khoom siv zoo tagnrho hauv ntau daim ntawv thov. Hauv tsab xov xwm no, peb soj ntsuam qhov xwm txheej uas cuam tshuam rau cov dej tuav tseg ntawm HPMC thiab yuav ua li cas thiaj ua tau zoo rau kev ua kom zoo siab txog lawv cov txiaj ntsig.
1. Molecular hnyav
Lub cev hnyav molecular ntawm HPMC ua si lub luag haujlwm tseem ceeb hauv nws cov khoom siv dej kom ceev. Qhov siab dua cov molecular hnyav, qhov ntau dua cov peev txheej hauv dej. Qhov no yog vim tias siab molecular hnyav HPMC muaj cov visccosity ntau dua, uas ua rau nws ua ib zaj duab xis tuab rau saum npoo ntawm substrate, yog li txo dej poob. Yog li ntawd, rau cov ntawv thov uas cov dej rov qab yog qhov tseem ceeb, qhov hnyav molecular hnyav HPMC tau pom zoo.
2. Qib ntawm kev hloov pauv
Cov qib degree hloov pauv (DS) yog hais txog tus naj npawb ntawm hydroxypropyl thiab methyl pawg hauv HPMC molecule. Lub siab dua DS, qhov muaj peev xwm ua kom muaj peev xwm kav dej ntau dua. Qhov no vim tias cov pawg methroxropyl thiab methyl pawg ua kom lub solubility ntawm HPMC hauv dej thiab txhim kho nws cov peev xwm los ua cov khoom siv gel zoo li uas tuaj yeem haum dej lwg me me. Yog li ntawd, rau cov ntawv thov uas cov dej rov qab yog qhov tseem ceeb tshaj plaws, HPMC nrog cov qib siab hloov pauv yog pom zoo.
3. Kub thiab av noo
Qhov kub thiab cov av noo yog qhov tseem ceeb cuam tshuam rau cov dej tuav tseg ntawm HPMC. Kev kub siab thiab muaj cua noo yuav ua rau cov dej hauv HPMC zaj duab xis mus rau teb sai sai, ua rau cov dej tsis zoo. Yog li, nws pom zoo kom khaws HPMC nyob rau hauv qhov chaw txias thiab qhuav los tswj nws cov dej-khaws cov khoom.
4. PHEEJ
Cov PH ntawm cov txheej txheem nkaus xwb ua si lub luag haujlwm tseem ceeb hauv cov dej tuav tseg ntawm HPMC. HPMC yog qhov ua tau zoo tshaj plaws rau cov kua qaub me ntsis. Thaum lub ph ntawm matrix yog siab, lub solubility ntawm HPMC tuaj yeem txo thiab cov nyhuv kom tsawg yuav raug txo kom tsawg. Yog li ntawd, nws raug nquahu kom sim ntsuas PH ntawm substrate thiab kho nws mus rau cov khoom siv tau zoo rau kev ua kom muaj txiaj ntsig zoo.
5. Lub siab
Cov concentration ntawm HPMC tseem cuam tshuam nws cov khoom siv dej kom ceev. Feem ntau, qhov siab dua ntawm HPMC, qhov zoo dua cov dej khaws cia. Txawm li cas los xij, ntawm kev muaj ntau heev, lub viscosity ntawm HPMC tuaj yeem dhau los ua qhov siab dhau, ua rau nws nyuaj rau kev thov thiab kis tusyees ntawm substrate. Yog li ntawd, nws raug nquahu kom sim qhov zoo tshaj plaws concentration ntawm HPMC rau txhua daim ntawv thov tshwj xeeb kom ua tiav cov dej ua kom zoo tshaj plaws.
Hauv kev xaus, HPMC tau dhau los ua cov khoom tseem ceeb vim nws cov khoom siv dej zoo heev thiab ua lub luag haujlwm tseem ceeb hauv kev lag luam ntau yam. Yam cuam tshuam rau nws cov dej khaws cia, xws li kev hnyav molecular, degree hloov chaw, ua kom zoo dua qub, tuaj yeem ua kom zoo dua qub. Los ntawm kev nkag siab txog cov yam no, peb tuaj yeem ua kom paub tseeb tias HPMCs ncav cuag lawv lub peev xwm, ua rau kev tsim cov khoom zoo rau lawv cov khoom siv dej.
Lub Sijhawm Post: Jul-04-2023