Npaj Hydroxypropyl Methylcellulose (HPMC) txheej txheej yog txheej txheem tseem ceeb hauv kev lag luam tshuaj thiab zaub mov. HPMC yog cov khoom siv polymer feem ntau hauv cov txheej txheem txheej vim nws cov yeeb yaj kiab zoo tshaj plaws, kev ruaj ntseg, thiab kev sib raug zoo nrog ntau yam khoom xyaw. Cov kev daws teeb meem yog siv los muab cov txheej txheem tiv thaiv, tswj kev tso tawm cov ntaub ntawv, thiab txhim kho cov tsos thiab kev ua haujlwm ntawm cov ntsiav tshuaj, tshuaj ntsiav, thiab lwm cov ntaub ntawv ntau npaum li cas.
1. Khoom siv:
Hydroxypropyl Methylcellulose (HPMC)
Cov kuab tshuaj (feem ntau yog dej los yog sib tov dej thiab cawv)
Plasticizer (yeem, txhawm rau txhim kho qhov yooj yim ntawm zaj duab xis)
Lwm yam additives (optional, xws li colorants, opacifiers, los yog anti-tacking agents)
2. Cov khoom siv xav tau:
Sib tov lub nkoj los yog thawv
Stirrer (mechanical lossis magnetic)
Ntsuas qhov ntsuas
Cua sov qhov chaw (yog tias xav tau)
Sieve (yog tias tsim nyog los tshem tawm pob)
pH meter (yog tias tsim nyog hloov pH)
Safety iav ( hnab looj tes, looj tsom iav dub, lab lub tsho tiv no)
3. Cov txheej txheem:
Kauj Ruam 1: Ntsuas cov khoom xyaw
Ntsuas qhov xav tau kom muaj nuj nqis ntawm HPMC siv qhov ntsuas qhov hnyav. Tus nqi yuav txawv nyob ntawm seb qhov xav tau ntawm cov tshuaj txheej txheej thiab qhov loj ntawm batch.
Yog tias siv plasticizer lossis lwm yam khoom siv ntxiv, ntsuas qhov xav tau kom muaj nuj nqis thiab.
Kauj Ruam 2: Kev npaj cov kuab tshuaj
Txiav txim siab hom kuab tshuaj los siv raws li daim ntawv thov thiab kev sib raug zoo nrog cov khoom xyaw nquag.
Yog tias siv dej ua cov kuab tshuaj, xyuas kom meej tias nws yog purity siab thiab zoo dua distilled los yog deionized.
Yog tias siv cov dej sib tov sib xyaw thiab dej cawv, txiav txim siab qhov sib piv uas tsim nyog raws li kev solubility ntawm HPMC thiab cov yam ntxwv xav tau ntawm cov tshuaj txheej txheej.
Kauj Ruam 3: Sib tov
Muab lub nkoj sib tov rau ntawm stirrer thiab ntxiv cov kuab tshuaj.
Pib nplawm cov kuab tshuaj ntawm ib tug nruab nrab ceev.
Maj mam ntxiv cov hmoov ua ntej hnyav HPMC rau hauv cov kuab tshuaj nplawm kom tsis txhob clumping.
Txuas ntxiv stirring kom txog thaum HPMC hmoov yog dispersed uniformly nyob rau hauv cov kuab tshuaj. Cov txheej txheem no yuav siv sij hawm me ntsis, nyob ntawm qhov concentration ntawm HPMC thiab kev ua haujlwm ntawm cov khoom siv stirring.
Kauj Ruam 4: Cua sov (yog tias xav tau)
Yog hais tias HPMC tsis yaj tag nrho ntawm chav tsev kub, maj mam cua sov yuav tsim nyog.
Tshav kub qhov sib tov thaum nplawm kom txog thaum HPMC yaj tag. Ceev faj kom tsis txhob kub dhau, vim qhov kub thiab txias tuaj yeem degrade HPMC lossis lwm yam tshuaj ntawm cov tshuaj.
Kauj Ruam 5: Ntxiv cov yas thiab lwm yam khoom ntxiv (yog tias tsim nyog)
Yog tias siv cov yas yas, ntxiv rau cov tshuaj maj mam thaum nplawm.
Ib yam li ntawd, ntxiv lwm yam uas xav tau ntxiv xws li cov xim lossis cov opacifiers ntawm theem no.
Kauj Ruam 6: Kev hloov pH (yog tias tsim nyog)
Txheeb xyuas pH ntawm cov tshuaj pleev xim siv lub ntsuas pH.
Yog tias pH tawm ntawm qhov xav tau ntau yam rau kev ruaj ntseg lossis kev sib haum xeeb, kho nws los ntawm kev ntxiv me me ntawm cov kua qaub lossis cov ntsiab lus yooj yim raws li.
Do cov tshuaj kom huv si tom qab txhua qhov sib ntxiv thiab rov kuaj xyuas pH kom txog thaum qib siab xav tau tiav.
Kauj Ruam 7: Kev sib xyaw zaum kawg thiab kev sim
Thaum tag nrho cov khoom xyaw ntxiv thiab sib tov kom huv si, txuas ntxiv stirring rau ob peb feeb ntxiv kom ntseeg tau tias homogeneity.
Ua ib qho kev ntsuam xyuas zoo xws li kev ntsuas viscosity lossis kev tshuaj xyuas qhov muag rau cov cim qhia ntawm cov teeb meem los yog theem sib cais.
Yog tias xav tau, dhau qhov kev daws teeb meem los ntawm lub sieve kom tshem tawm cov khoom seem lossis cov khoom uas tsis tau muab tshem tawm.
Kauj Ruam 8: Cia thiab ntim
Hloov cov tshuaj HPMC txheej txheej npaj rau hauv cov thawv ntim khoom tsim nyog, nyiam dua amber iav fwj lossis cov thawv yas zoo.
Sau cov thawv nrog cov ntaub ntawv tsim nyog xws li batch tooj, hnub ntawm kev npaj, concentration, thiab kev cia khoom.
Khaws cov tshuaj rau hauv qhov chaw txias, qhuav, tiv thaiv lub teeb thiab noo noo kom nws ruaj khov thiab txee lub neej.
4. Lub tswv yim thiab kev txiav txim siab:
Yuav tsum ua raws li kev soj ntsuam zoo thiab cov lus qhia kev nyab xeeb thaum tuav cov tshuaj thiab khoom siv.
Ua kom huv thiab ua kom tsis muaj menyuam thoob plaws hauv txoj kev npaj kom tsis txhob muaj kab mob.
Ntsuam xyuas cov kev sib raug zoo ntawm cov txheej txheej nrog cov txheej txheem npaj (cov ntsiav tshuaj, tshuaj ntsiav) ua ntej daim ntawv thov loj.
Ua cov kev tshawb fawb txog kev ruaj ntseg los ntsuas qhov kev ua tau zoo mus sij hawm ntev thiab kev cia khoom ntawm txheej txheej.
Sau cov txheej txheem kev npaj thiab khaws cov ntaub ntawv rau lub hom phiaj kev tswj kom zoo thiab kev ua raws cai.
Post lub sij hawm: Mar-07-2024