Hydroxypropyl methylcellulose (HPMC) yog ib qho polymer muab tau los ntawm cellulose thiab feem ntau siv nyob rau hauv ntau yam lag luam, xws li tshuaj, tshuaj pleev ib ce, thiab zaub mov. Nws yog cov dej-soluble polymer uas tuaj yeem yooj yim hydrated los tsim cov kua dej khov.
1. Nkag siab txog HPMC:
Ua ntej sib tham txog cov txheej txheem hydration, nws yog ib qho tseem ceeb kom nkag siab txog cov yam ntxwv ntawm HPMC. HPMC yog ib tug semi-synthetic polymer uas yog hydrophilic, lub ntsiab lus nws muaj ib tug muaj zog affinity rau dej. Nws tsim pob tshab, hloov tau, thiab ruaj khov gels thaum hydrated, ua rau nws haum rau ntau yam kev siv.
2. Cov txheej txheem dej:
Lub hydration ntawm HPMC suav nrog dispersing cov polymer hmoov nyob rau hauv dej thiab tso cai rau nws o los ua ib tug viscous kua los yog gel. Nov yog cov lus qhia ua ntu zus rau kev ua kom dej HPMC:
Xaiv Qib Siab:
HPMC muaj nyob rau hauv ntau qib nrog sib txawv molecular luj thiab viscosity qib. Kev xaiv ntawm qib tsim nyog nyob ntawm qhov xav tau viscosity ntawm cov tshuaj kawg lossis gel. Cov qib molecular hnyav dua feem ntau ua rau cov viscosity ntau dua.
Npaj Cov Dej:
Siv dej huv los yog deionized rau hydrating HPMC kom tsis muaj impurities uas yuav cuam tshuam cov khoom ntawm cov tshuaj. Qhov kub ntawm cov dej kuj tuaj yeem cuam tshuam cov txheej txheem hydration. Feem ntau, siv dej kub hauv chav tsev yog txaus, tab sis cua sov cov dej me ntsis tuaj yeem ua kom cov txheej txheem hydration.
Dispersion:
Maj mam nplawm cov hmoov HPMC rau hauv dej thaum nplawm tsis tu ncua kom tiv thaiv kev tsim cov clumps. Nws yog ib qho tseem ceeb uas yuav tsum tau ntxiv cov polymer maj mam kom ntseeg tau tias muaj kev sib cais thiab tiv thaiv agglomeration.
Dej:
Txuas ntxiv sib tov kom txog thaum tag nrho cov hmoov HPMC tau tawg mus rau hauv dej. Cia cov sib tov sawv ntsug rau lub sijhawm txaus kom tso cai rau cov khoom siv polymer kom o thiab hydrate tag nrho. Lub sij hawm hydration tuaj yeem sib txawv raws li qhov kub thiab txias, qib polymer, thiab qhov xav tau viscosity.
Kev sib xyaw thiab homogenization:
Tom qab lub sij hawm hydration, sib tov cov tshuaj kom huv si kom ntseeg tau tias uniformity. Nyob ntawm daim ntawv thov, kev sib xyaw ntxiv lossis homogenization yuav tsim nyog kom ua tiav qhov kev xav tau sib xws thiab tshem tawm cov pob uas seem.
Kho pH thiab Additives (yog tias tsim nyog):
Nyob ntawm daim ntawv thov tshwj xeeb, koj yuav tsum tau kho cov pH ntawm cov tshuaj siv cov kua qaub lossis cov hauv paus. Tsis tas li ntawd, lwm yam khoom siv ntxiv xws li cov tshuaj tua kab mob, cov yas yas, lossis cov thickeners tuaj yeem muab tso rau hauv cov tshuaj nyob rau theem no los txhim kho nws cov kev ua tau zoo lossis kev ruaj ntseg.
Lim (yog tias tsim nyog):
Qee zaum, tshwj xeeb tshaj yog nyob rau hauv kev siv tshuaj los yog tshuaj pleev ib ce, lim cov tshuaj hydrated tej zaum yuav tsim nyog los tshem tawm cov khoom tsis muaj dej los yog cov impurities, uas ua rau cov khoom pom tseeb thiab zoo ib yam.
3. Kev siv ntawm Hydrated HPMC:
Hydrated HPMC pom cov ntawv thov hauv ntau qhov kev lag luam:
- Pharmaceutical Industry: Hauv cov tshuaj formulations, hydrated HPMC yog siv los ua ib tug thickening agent, binder, thiab film-forming tus neeg saib xyuas nyob rau hauv ntsiav tshuaj coatings.
- Kev lag luam tshuaj pleev ib ce: HPMC feem ntau yog siv rau hauv cov khoom siv tshuaj pleev ib ce xws li cream, tshuaj pleev, thiab gels ua cov thickener, stabilizer, thiab cov neeg ua yeeb yaj kiab.
- Kev Lag Luam Khoom Noj: Hauv kev lag luam khoom noj khoom haus, hydrated HPMC yog siv los ua cov thickener, emulsifier, thiab stabilizer hauv cov khoom xws li kua ntses, hnav khaub ncaws, thiab cov khoom siv mis nyuj.
- Kev Lag Luam Kev Tsim Kho: HPMC yog siv rau hauv cov khoom siv xws li mortars, grouts, thiab pobzeb nplaum los txhim kho kev ua haujlwm, dej tuav, thiab adhesion.
4. Xaus:
Hydroxypropyl methylcellulose (HPMC) yog ntau yam polymer uas tuaj yeem yooj yim hydrated los tsim cov kua nplaum los yog cov gels. Cov txheej txheem hydration suav nrog dispersing HPMC hmoov hauv dej, tso cai rau nws o, thiab sib tov kom ua tiav qhov sib xws. Hydrated HPMC pom cov ntawv thov hauv ntau qhov kev lag luam, suav nrog tshuaj, tshuaj pleev ib ce, zaub mov, thiab kev tsim kho. Kev nkag siab txog cov txheej txheem hydration thiab cov khoom ntawm HPMC yog qhov tseem ceeb rau kev ua kom nws qhov kev ua tau zoo hauv ntau daim ntawv thov.
Post lub sij hawm: Mar-19-2024