HPMC rau zaj duab xis txheej

HydroxyPropy Cellulose (HPMC) feem ntau siv hauv kev lag luam kws tshuaj uas muaj kev zam rau hauv zaj duab xis ua yeeb yam. Zaj duab xis txheej yog ib tug txheej txheem uas ib qho kev nyias nyias, ib qho kev sib tw ntawm polymer yog siv rau cov ntaub ntawv dosage, xws li ntsiav tshuaj lossis tshuaj ntsiav. HPMC muaj ntau qhov zoo nyob rau hauv zaj duab xis txheej ntawv thov, suav nrog zaj duab xis, adhesion, thiab tswj cov khoom tso tawm. Ntawm no yog ib qho ntsiab lus tshaj tawm ntawm cov ntawv thov, cov haujlwm, thiab kev txiav txim siab ntawm HPMC hauv Zaj Duab Xis:

1. Taw qhia rau hydroxypropyl methyl cellulose (HPMC) hauv Zaj Duab Xis

1.1 lub luag haujlwm nyob rau hauv zaj duab xis txheej formulations

HPMC yog siv los ua zaj duab xis-ua tus neeg sawv cev hauv cov tshuaj yeeb yaj kiab txheej. Nws muab cov txheej du thiab uniform du thiab uniform rau ntawm cov npoo ntawm cov ntaub ntawv dosage ruaj khov, koom tes rau lawv cov tsos, thiab yooj yim ntawm nqos.

1.2 Cov txiaj ntsig hauv cov ntawv thov ua yeeb yam

• Zaj duab xis tsim: HPMC ua ib zaj yeeb yaj kiab hloov tau thiab pob tshab thaum ua ntawv thov rau saum cov ntsiav tshuaj lossis cov tsiav tshuaj, muab kev tiv thaiv thiab txhim kho kev tiv thaiv.
• Adhesion: HPMC txhim kho adhesion, kom ntseeg tau cov yeeb yaj kiab adheres uniformly rau lub substrate mus rau substrate thiab tsis tawg lossis tev.
• Kev tso tawm kev tso tawm: Nyob ntawm cov qib tshwj xeeb siv, HPMC tuaj yeem pab txhawb rau kev tswj hwm kev tswj hwm ntawm cov tshuaj muaj zog (API) los ntawm daim foos.

2. Kev ua haujlwm ntawm HydroxyPropy kasthyl cellulose hauv zaj duab xis txheej

2.1 zaj duab xis tsim

HPMC ua raws li zaj duab xis-tsim tus neeg sawv cev, tsim cov yeeb yaj kiab nyias thiab tsis zoo ntawm cov ntsiav tshuaj lossis tshuaj ntsiav. Daim yeeb yaj kiab no muab kev tiv thaiv, npog ntsej muag kom saj lossis tsw qab ntawm cov tshuaj, thiab txhim kho qhov tsos tag nrho.

2.2 Adhesion

HPMC txhim kho adhesion nruab nrab ntawm zaj duab xis thiab lub substrate, ua kom muaj kev ruaj khov thiab ruaj khov. Cov adhesion kom tsim nyog tiv thaiv cov teeb meem xws li kev tawg lossis tshaj tawm thaum lub sijhawm khaws cia lossis tuav.

2.3 Tshuaj Tso Tawm

Qee cov qhab nia ntawm HPMC yog tsim los pab txhawb kev tawm-tso tawm, cuam tshuam kev tso tawm ntawm cov khoom siv nquag los ntawm kev siv tshuaj. Qhov no yog qhov tshwj xeeb tshaj yog rau ncua-tso tawm lossis kev tso tawm kom raug.

2.4 Kev Txhim Kho Kev Zoo Nkauj

Kev siv HPMC nyob rau hauv zaj duab xis txheej ua yeeb yam tuaj yeem txhim kho cov kev pom zoo ntawm cov nqi, ua rau cov neeg mob. Zaj duab xis muab txoj kev du thiab ci ua tiav.

3. Cov ntawv thov hauv zaj duab xis txheej

3.1 ntsiav tshuaj

HPMC feem ntau yog siv rau cov ntsiav tshuaj ua ke, muab cov txheej tiv thaiv thiab txhim kho lawv cov tsos. Nws yog haum rau ntau cov ntsiav tshuaj ua qauv, nrog rau kev tso tawm tam sim thiab txuas ntxiv-tso tawm.

3.2 tsiav tshuaj

Ntxiv rau cov ntsiav tshuaj, HPMC yog siv rau zaj duab xis txheej ntsiav tshuaj, pab txhawb lawv cov kev ruaj khov thiab muab cov khaub ncaws hnav zoo nkauj. Qhov no yog qhov tshwj xeeb tshaj yog rau saj-los yog ntxhiab-rawv-rhiab.

3.3 saj daim npog

HPMC tuaj yeem ua haujlwm los npog ntsej muag lossis tsw ntawm cov tshuaj muaj zog, txhim kho tus neeg mob kom muaj kev lees paub lossis geriatric lossis geriatric lossis geriatric.

3.4 Cov Tshuaj Tso Tawm-Tso Tawm

Rau kev tswj hwm-tso tawm lossis kev tso tawm cov yeeb yaj kiab, HPMC plays yog lub luag haujlwm tseem ceeb hauv kev ua tiav cov ntaub ntawv tso tawm, tso cai rau kev tawm hauv cov yeeb tshuaj ntxiv thiab tswj tau cov tshuaj.

4. Kev txiav txim siab thiab ceev faj

4.1 Qeb Xaiv

Cov qib kev xaiv HPMC yuav tsum yog raws li cov kev cai ua yeeb yaj kiab ntawm zaj duab xis, suav nrog cov khoom ua yeeb yaj kiab xav tau, nrog rau cov yam ntxwv tso tawm.

4.2 kev sib raug zoo

Kev sib xyaw nrog lwm cov tshuaj lom thiab cov khoom muaj tshuaj lom neeg yog qhov tseem ceeb kom ntseeg tau tias qhov kev ruaj ntseg thiab ua yeeb yam ntawm zaj duab xis-coated Dosage.

4.3 FRIY DICKNESS

Lub thickness ntawm zaj duab xis yuav tsum tau ua tib zoo tswj kev cai thiab kom zam cov teeb meem xws li txheej xwm txheej, uas yuav cuam tshuam cov kev sib txawv thiab cov kab ke.

5. Xaus

HydroxyPropy cellulose yog qhov muaj txiaj ntsig zoo nyob rau hauv cov ntaub ntawv zaj duab xis txheej, muab zaj duab xis, thiab tswj-tso tawm cov khoom. Film-coated Dosage cov foos muab txhim kho kom zoo nkauj, kev tiv thaiv, thiab tus neeg mob kev txuag. Ua tib zoo xav txog qib qib, sib xyaw, thiab zaj duab xis yog qhov tsim nyog los xyuas kom meej daim ntawv thov HPMC nyob rau hauv zaj duab xis sib txawv.