HydroxyPropyyl nrho methyl cellulose raws li lub chaw muag tshuaj

HydroxyPropylropy Cellulose (HPMC)Puas yog ib qho kev siv hluav taws xob ntau ntxiv rau hauv ntau cov kev siv tshuaj ntau yam vim nws cov khoom tshwj xeeb. Qhov no cellulose derivative yog muab los ntawm cellulose, ib qho tshwm sim polymer pom hauv cov nroj tsuag, thiab hloov kho los ntawm kev siv tshuaj lom tau kom tau txais cov yam ntxwv xav tau. Hauv cov tshuaj ntawm cov tshuaj, HPMC pabcuam ntau lub zog, suav nrog binder, zaj duab xis yav tas los, thickener, stabilizer, thiab tus neeg sawv cev tawm. Nws cov ntawv thov thoob plaws thiab qhov tseem ceeb hauv kev lag luam kev lag luam muag tau lees paub txog nws cov khoom, cov ntawv thov, thiab cov kev thov.

HPMC's Solubility thiab Viscosity Cov Protures ua nws qhov kev xaiv zoo rau kev tswj yeeb tshuaj tso tawm hauv daim ntawv foos. Nws tsim gel matrix li dej, uas tuaj yeem rov qab tso yeeb tshuaj tawm los ntawm kev sib txawv ntawm cov txheej gel o. Lub viscosity ntawm gel nyob ntawm yam xws li molecular hnyav, qib ntawm hloov hpmc hauv kev tsim qauv. Los ntawm kev hloov cov kev ntsuas no, cov kws tshawb fawb tshuaj tuaj yeem kho cov txiaj ntsig tshuaj kom ua tiav cov txiaj ntsig tshuaj kom ua tiav kom ua tiav cov txiaj ntsig xav tau, xws li tso tawm cov uas xav tau, lossis tso tawm.

HPMC feem ntau siv los ua cov phau ntawv tsim qauv rau imfart cohesiveness thiab txhim kho cov mechanical lub zog ntawm cov ntsiav tshuaj. Raws li cov phau ntawv, nws txhawb nqa cov khoom nplaum thiab cov tshuab raj granule thaum lub ntsiav tshuaj Compression cov txheej txheem, ua rau cov ntsiav tshuaj muaj kev sib txuam. Tsis tas li ntawd, HPMC zaj duab xis-tsim cov khoom ua nws haum rau cov ntsiav tshuaj, uas tau saj npog, kev tiv thaiv noo noo, thiab kho cov tshuaj tso tawm.

Ntxiv nrog rau qhov ncauj noj tshuaj, HPMC pom daim ntawv thov hauv lwm cov kev daws teeb meem, suav nrog cov ntsiab lus ophthalmic, cov ntsiab lus opicical, thiab cov kev tawm tsam-tso tawm. Hauv ophthalmic daws, hpmc ua raws li tus neeg sawv cev viscosity - txhim kho lub sijhawm nyob ntawm cov qauv ntawm kev nqus cov tshuaj uas muaj kuab. Hauv cov tsos gels, nws muab rheator tswj, tso cai rau kev thov kom yooj yim thiab txhim kho daim tawv nqaij nkag mus rau cov khoom xyaw nquag.

HPMC-Zajased transdermal thaj ua rau thaj chaw muaj qhov yooj yim thiab tsis muaj tshuaj rau kev siv tshuaj rau kev kho mob lossis kev kho mob hauv zos. Cov polymer matrix tswj cov tawv nqaij tso tawm los ntawm cov tawv nqaij ntxiv, tswj cov tshuaj siv tshuaj nyob rau hauv cov hlab ntshav thaum tsis muaj kev hloov pauv. Qhov no yog qhov tshwj xeeb rau cov tshuaj nrog kev siv lub qhov rais nqaim lossis cov uas yuav tsum tau tswj hwm txuas ntxiv.

HPMC's biocompatibility thiab inertness ua rau nws haum rau siv nyob rau hauv cov niam txiv cov kev ua niam ua txiv raws li kev ncua tus neeg sawv cev lossis viscosity hloov. Hauv kev tswj hwm-tso tawm hauv cov tshuaj tiv thaiv, HPMC tsim nyog tuaj yeem enceptified cov tshuaj molecules, yog li txo cov nqi tshuaj thiab txhim kho cov neeg mob ua raws.

HPMC cov khoom ua pov thawj mucoDhesive cov khoom, ua rau nws muaj txiaj ntsig zoo tsim rau kev xa tshuaj mucosal, xws li cov yeeb yaj kiab siv tshuaj yeeb yaj kiab thiab cov tshuaj nasal. Los ntawm adhering rau mucosal nto, HPMC Exolongs Tshuaj Lub Sijhawm, tso cai rau kev nqus tshuaj kom zoo thiab cov xyoob ntoo.

HPMC feem ntau tau pom tias muaj kev nyab xeeb (Gras) los ntawm cov tub ceev xwm kev tswj hwm xws li Asmeskas Chaw Tswj Khoom Noj (FDA), ua rau kev siv hauv kev siv rau tib neeg. Nws cov biodegradity thiab tsis muaj tshuaj lom tus nqi ntxiv pab rau nws cov lus thov rov hais dua los ntawm cov chaw muag tshuaj.

HydroxyPropylropy Cellulose (HPMC)Puas yog ib qho kev zam ntawm kev saib xyuas nrog ntau cov ntawv thov hla ntau cov ntaub ntawv. Nws cov khoom tshwj xeeb, suav nrog solubility, suav nrog solubility, ua yeeb yaj kiab ua yeeb yaj kiab, thiab biocompatibility, thiab biocompatibility muaj peev xwm ua yeeb yam hauv kev ua tiav cov hom phiaj kev kho mob tshwj xeeb. Raws li kev tshawb fawb ntawm cov chaw tshuaj txuas ntxiv mus hloov zuj zus, HPMC yuav nyob twj ywm rau hauv lub hauv paus kom zoo rau kev txhim kho cov khoom siv tshuaj tshiab thiab cov qauv.