Hydroxyprropyloostrose (HPMC) yog siv ntau yam uas tau siv dav hauv ntau yam kev lag luam vim nws cov khoom muaj txiaj ntsig. Qhov no sib xyaw no yog ib qho tseem ceeb ntawm cellulose, lub ntuj polymer pom hauv tsob ntoo cell phab ntsa. Cov synthesis ntawm HPMC koom nrog kho cellulose nrog prinylene oxide los qhia cov pab pawg hydroxyproproundyl thiab nrog methyl chloride los qhia methyl pawg. Lub txiaj ntsig polymer ua kom muaj cov khoom siv thiab tshuaj lom neeg, ua kom haum rau siv hauv chaw tsim tshuaj, kev tsim kho, khoom noj thiab lwm yam lag luam.
1. DiCemical qauv thiab muaj pes tsawg leeg:
HydroxyPropyyl methylulose yog ib nrab hluavtaws polymer nrog cov qauv tshuaj sib luag. Lub polymer lub caj qaum muaj cov cellulose, txoj kab sib dhos ntawm cov piam thaj molecules molecules txuas los ntawm β-1,4-glycosidic bonds. Cov pab pawg hydroxypropyl tau qhia los ntawm kev hloov cov pab pawg hydroxyl (-oh) nrog cov pab pawg hydroxyl (thiab pawg methyl pab pawg. Cov qib degree (DS) sawv cev rau cov pawg nruab nrab ntawm hydroxypropyl ib pawg twg thiab cuam tshuam rau cov solubility thiab cuam tshuam rau cov khoom, viscosity, thiab cua sov cov khoom ntawm cov polymer.
2. Solubility:
Ib qho ntawm cov yam ntxwv txawv ntawm HPMC yog nws tus cwj pwm xaus. Nws yog soluble hauv ob qho tib si txias thiab dej kub, muab cov txiaj ntsig tshwj xeeb hauv ntau yam kev siv. Solubility tuaj yeem hloov kho los ntawm kev kho cov qib degree hloov chaw thiab hnyav hnyav ntawm cov polymer. Cov cuab yeej no ua rau HPMC ib tug neeg sib tw zoo tshaj plaws rau kev muab tshuaj-tso cov tshuaj tiv thaiv yeeb tshuaj, qhov twg cov lus qhia txog kev sib cav sib ceg hauv cov tshuaj uas tsis muaj tshuaj tiv thaiv kinetics.
3. Viscosity:
HydroxyPropyyl methylcellulose muaj nyob rau hauv ntau yam ntawm ntau yam xws li molecular hnyav, degree hloov chaw, thiab kev daws teeb meem. Lub viscos ntawm HPMC cov kev daws teeb meem tso cai rau lawv siv rau hauv cov ntawv thov kev lag luam, suav nrog cov khoom siv tshuaj, thiab ua cov ntaub ntawv ua yeeb yam rau txheej.
4. Zaj duab xis-ua kev ua tau zoo:
Cov yeeb yaj kiab ua yeeb yam ntawm HPMC yog qhov tseem ceeb hauv kev thov siv tshuaj tiv tshuaj, qhov chaw uas nws tau siv cov tshuaj tiv thaiv cov tshuaj, tswj cov tshuaj, thiab txhim kho kev ruaj khov. HPMC zaj duab xis yog tseeb thiab hloov tau, thiab lawv cov khoom tuaj yeem raug tsim kho los ntawm kev kho kom haum, hnyav hnyav thiab cov ntsiab lus yas.
5. Thermal Performance:
HydroxyPropyyl methylculose cov khoom ua kom zoo ua kom zoo thermal ruaj nras tsis pub dhau qhov ntsuas kub tshwj xeeb. Thermal cov khoom muaj cuam tshuam los ntawm cov lus xws li qib deg ntawm hloov chaw, hnyav hnyav, thiab muaj cov yas. Cov khoom siv HPMC haum rau cov ntawv thov uas thermal stability yog qhov tseem ceeb, xws li kev npaj ntawm cov tshuaj tiv thaiv cua sov-rhiab.
6. Biocompatibility:
Hauv cov chaw tshuaj thiab biomedical teb, biocompatibility yog qhov kev txiav txim siab tseem ceeb rau cov ntaub ntawv siv tshuaj. HydroxyPropyyl methylcellulose yog feem ntau suav hais tias muaj kev nyab xeeb thiab muaj zoo biocompatibility. Nws yog dav siv nyob rau hauv kev tsim cov ntaub ntawv ntawm cov tshuaj noj, cov kev daws teeb meem ophthalmic thiab tswj hwm-tso tawm tshuaj.
7. Dej khaws cia thiab thickenies cov khoom:
HPMC muaj peev xwm khaws cov dej thiab cov kev daws teeb meem ua rau nws muaj txiaj ntsig zoo hauv cov khoom tsim kho xws li cov khoom noj khoom haus cement. Hauv cov ntawv thov no, HPMC ua haujlwm rau dej tuav tus neeg sawv cev, txhim kho cov txheej txheem kom qhuav kom qhuav ntawm cov khoom. Thickening cov khoom kuj tseem siv ntau yam khoom noj los txhim kho kev ntxhib los mos thiab qhov ncauj.
8. Tshuaj tiv thaiv-tso tawm tshuaj
Ib qho ntawm cov ntawv thov tseem ceeb ntawm hydroxypropyf methylcellose yog nyob rau hauv kev tsim ntawm kev tawm tshuaj-tso cov tshuaj tawm tshuaj. Cov polymer's solubility, viscosity, thiab ua yeeb yaj kiab-thiab zaj duab xis-thiab zaj duab xis-thiab zaj duab xis-forming txhawb tswj kev tso tshuaj yeeb tshuaj, ua rau muaj kev xa tshuaj. Qhov no yog tau txais txiaj ntsig tshwj xeeb rau kev txhim kho kev ua raws kev ua raws cai thiab txo cov kev mob tshwm sim cuam tshuam nrog kev tso tawm sai.
9. Stability nyob rau hauv ib puag ncig ntau:
HPMC cov khoom pov thawj kev ruaj ntseg tshaj li cov dav ntev, ua rau nws haum rau cov qauv uas xav tau kev ruaj ntseg hauv qab lossis alkaline. Cov cuab yeej no yog qhov zoo hauv chaw tshuaj vim tias yuav sib tw sib tw sib txawv hauv cov plab zom mov.
10. Rheological yam ntxwv:
Kev daws teeb meem ntawm HPMC yog qhov tseem ceeb rau kev siv rau qhov twg ntws tawm, xws li nyob rau hauv kev npaj ntawm txheej, adhesives thiab gels. Lub zog rheological tuaj yeem ua kom haum los ntawm kev kho cov kev xav thiab kev ua haujlwm hnyav ntawm HPMC kom ua tiav cov yam ntxwv txaus rau kev tswj hwm.
HydroxyPropyyl methylcellulose tau dhau los ua ntau yam kev lag luam vim nws cov kev lag luam tshwj xeeb ntawm solubility, viscosity, yeeb yaj kiab ua yeeb yaj kiab thiab biocompatibility. Nws cov vagatility ua rau nws haum rau ntau cov ntawv thov, los ntawm cov tshuaj thiab cov khoom siv rau cov khoom noj thiab cov tshuaj pleev ib ce. Raws li cov kws tshawb nrhiav txuas ntxiv tshawb cov qauv tshiab thiab cov ntawv thov, ua kom muaj kev sib txuas lus hauv ntau yam hauv kev ua haujlwm hauv ntau qhov kev tshawb fawb thiab kev lag luam.
Lub Sijhawm Post: Jan-10-2024