HydroxyPropyyl methylcellulose (HPMC)Yog cov dej-soluble cov khoom siv polymer siv hauv kev tsim kho, tshuaj, khoom noj thiab tshuaj pleev ib ce. Hauv kev ib puag ncig vaum, kev ua haujlwm ntawm HPMC cuam tshuam los ntawm ntau yam, thiab nws cov yam ntxwv txiav txim siab nws txoj kev yoog tau thiab ruaj khov nyob rau hauv cov ntawv thov sib txawv.
1. Hygroscopicity
HPMC yog cov khoom siv hydrophricic nrog cov khoom siv hydroscopicity muaj zog. Nyob rau hauv ib puag ncig, HPMC tuaj yeem nqus noo noo los ntawm huab cua, uas yog feem ntau yog muaj ntau pawg hydroxyl thiab methoxy pawg nyob rau hauv nws cov qauv molecular. Cov hygroscopicity no ua ib txheej ntawm dej zaj duab xis los tsim nyob rau ntawm HPMC, ua rau nws pom zoo dua cov yuag thiab cov nplaum. Cov cuab yeej no yog qhov tshwj xeeb tshaj nyob rau hauv cov ntaub ntawv tsim tsev. Piv txwv li, nyob rau hauv cov nplais nplaum thiab putty hmoov, HPMC tuaj yeem txhim kho kev tsim kho kev ua haujlwm thiab dej khaws cia ntawm cov khoom.
Txawm li cas los xij, ntau hygroscopicity yuav ua rau muaj teeb meem hauv qee cov ntawv thov. Piv txwv li, thaum HPMC yog siv los ua kev tswj cov ntsiav tshuaj, yuav hloov cov dej tso tawm tshuaj thiab cuam tshuam rau qhov muaj kev sib raug zoo ntawm kev noj tshuaj. Yog li ntawd, nyob rau hauv ib puag ncig vaum kev tsim qauv ntawm HPMC yuav tsum tau them nyiaj tshwj xeeb rau nws txoj kev coj ua hygroscopic.
2. Kev ruaj khov
HPMC feem ntau ua rau cov tshuaj muaj peev xwm ruaj khov nyob hauv ib puag ncig huab cua. Vim tias qhov tshwj xeeb kev hloov kho ntawm nws cov molecular chart, HPMC yog qhov ruaj khov nyob rau hauv ob lub acid thiab tsis yauv tsis muaj kev cuam tshuam tseem ceeb los yog tshuaj lom neeg cov av noo. Txawm li cas los xij, cov av noo siab yuav muaj qee yam cuam tshuam rau nws lub cev lub cev. Piv txwv li, tus lej ntawm HPMC yuav nrawm, thiab nws cov yam ntxwv viscosity tuaj yeem hloov vim yog dej noo nqus.
Txog kev kho cov ntawv thov, cov chaw vaum siab yuav ua rau cov dej volatilization hauv HPMC-hloov kho, yog li txuas lub sijhawm kom qhuav ntawm cov khoom siv kom qhuav ntawm cov khoom qhuav. Muaj qee kis, qhov no yuav tau zoo dua vim tias nws muab lub sijhawm ua haujlwm ntev dua. Txawm li cas los xij, cov av noo ntau yuav ua rau txo qis dua tom qab ziab lossis tawg rau saum npoo.
3. Dej tuav
HPMC muaj dej zoo heev rau cov khoom hauv cov chaw noo. Cov cuab yeej no ua rau nws tsis tseem ceeb ntxiv hauv kev tsim kho. Piv txwv li, thaum lub tshuab nqus phab ntsa, HPMC tuaj yeem tiv thaiv cov dej tsis txaus, yog li ua kom muaj sijhawm zoo los ua kom tiav cov tshuaj lom dej qhuav thiab txhim kho cov khoom siv ua kom zoo. Nyob rau hauv ib puag ncig noo, lub peev xwm kav dej tuaj yeem txhim kho ntxiv vim tias cov av noo hauv ib puag ncig muab cov khoom muaj ntxiv rau cov khoom siv.
4. Zaj duab xis-tsim muaj peev xwm
Kev ua yeeb yaj kiab ua yeeb yam muaj peev xwm ntawm HPMC tshwj xeeb tshwj xeeb hauv cov huab cua noo. Thaum HPMC kev daws teeb meem yog nthuav dav rau huab cua nrog cov av noo, tus neeg evaporation tus nqi ntawm cov dej qeeb, txhawb nqa kev ua yeeb yaj kiab. Zaj duab xis no muaj qhov yooj kev ua tau zoo thiab lub tensile tsis kam, thiab tuaj yeem muab cov khoom tawg ua tau zoo thiab cov khoom tiv thaiv dej rau cov cuab yeej kos duab rau cov cim ua yeeb yam. Nyob rau hauv cov zaub mov thiab cov duab qhia chaw, HPMC cov yeeb yaj kiab kuj tseem siv tau rau txheej thiab tiv thaiv cov khoom xyaw rhiab los ntawm kev cuam tshuam ntawm cov av noo.
5. Kev ntsuas kev tsim nyog hauv cov ntawv thov
Txhawm rau kom ua kom tau zoo ntawm HPMC hauv cov chaw muaj huab cua noo, ntau txoj kev hloov kho tau txais nyob rau hauv cov ntawv thov sib txawv. Piv txwv li, los ntawm kev kho cov qib ntawm HPMC, nws hygroscopicity thiab viscosity cov yam ntxwv tuaj yeem hloov tau; Hauv cov ntaub ntawv hauv tsev, nws cov kev ua tau zoo nyob rau hauv cov chaw muaj kev txhim kho ntau ntxiv los ntawm compounding nrog lwm cov hmoov sib ntxiv (xws li cov hmoov yas yas lossis tuab dua).
Kev ua yeeb yam ntawmHPMCHauv ib puag ncig huab cua yog cuam tshuam los ntawm ntau yam. Nws hygroscopicity, dej ceev thiab ua yeeb yaj kiab-tsim muaj peev xwm ua rau nws tau qhia tus nqi zoo heev hauv kev tsim kho, tshuaj thiab khoom noj. Txawm li cas los xij, ib puag ncig huab cua siab yuav nqa qee cov kev cov nyom, uas yuav tsum tau hais txog kev ntsuas tsim qauv thiab kev hloov kho. By deeply studying the behavior of HPMC in a humid environment, its characteristics can be better exerted to meet the needs of different fields.
Lub Sijhawm Post: Kaum-24-2024