HEC (Hydroxyethyl cellulose)yog ib hom dej-soluble polymer dav siv hauv kev npaj tshuaj. Nws yog qhov ua kom pom tseeb ntawm cellulose, tau los ntawm reacting ethanolamine (ethylene oxide) nrog cellulose. Vim nws cov solubility zoo, qhov ruaj khov, muaj peev xwm hloov kho muaj peev xwm ntawm cov ntaub ntawv kev tsim kho, HEC muaj kev tswj hwm cov tshuaj thiab kev siv yeeb tshuaj.
1. Cov khoom yooj yim ntawm HEC
HEC, raws li hloov kho cellulose, muaj cov khoom tseem ceeb hauv qab no:
Dej solubility: txhawj xeeb ®ec tuaj yeem tsim cov tshuaj tua kab hauv dej, thiab nws solubility muaj feem xyuam rau cov kub thiab Ph. Cov cuab yeej no ua rau nws siv ntau yam tshuaj ntau npaum li ntawm qhov ncauj thiab ntxig.
Biocompatibility: HEC yog tsis-toxic thiab tsis-irritating nyob rau hauv tib neeg lub cev thiab tau tshaj nrog ntau yam tshuaj. Yog li ntawd, nws yog dav siv nyob rau hauv kev txhawb nqa-tso cov ntaub ntawv thiab cov tswj hwm hauv zos noj tshuaj ntawm cov tshuaj.
Adjustable viscosity: lub viscosity ntawm HEC tuaj yeem hloov kho nws cov molecular hnyav lossis kev xav tau, uas yog cov tshuaj tso tawm lossis txhim kho cov tshuaj muaj peev xwm.
2. Daim ntawv thov ntawm HEC hauv Kev Npaj Ua Lag Luam
Raws li qhov tseem ceeb kom zoo rau kev npaj tshuaj, HEC muaj ntau txoj haujlwm. Hauv qab no yog nws cov ntawv thov tseem ceeb hauv kev npaj tshuaj.
2.1 Daim ntawv thov hauv kev npaj rau qhov ncauj
Hauv cov ntaub ntawv ntawm qhov ncauj noj, HEC feem ntau siv nyob rau hauv kev tsim cov ntsiav tshuaj, tsiav tshuaj thiab npaj ua kua. Nws lub ntsiab ua haujlwm suav nrog:
Binder: Hauv cov ntsiav tshuaj thiab cov granules, HEC tuaj yeem siv los ua phau ntawv sau cov tshuaj lossis hmoov ua ke kom paub meej thiab muaj kev ruaj ntseg ntawm cov ntsiav tshuaj.
Kev Ntsuas Kev Tso Tawm: HEC tuaj yeem ua tiav cov nyhuv tso tawm los ntawm kev tswj hwm cov tshuaj tso tawm. Thaum HEC siv ua ke nrog lwm cov khoom xyaw (xws li polyvinyl pyrrolidone, cov tshuaj carboxymethyl ntawm lub cev, thiab ntau zaus ntawm cov tshuaj, thiab txhim kho kev ua raws li kev ua raws.
Thickener: hauv cov kua dej npaj, ntxhov siab ®ec los ua cov tuab tuaj yeem txhim kho cov tshuaj thiab qhov muaj kev ruaj ntseg ntawm daim ntawv ntau npaum li cas.
2.2 Daim Ntawv Thov Hauv Kev Npaj Ua Yeeb Yam
HEC tau dav siv hauv cov tshuaj pleev ib yam, cov tshuaj cream, kua pleev, lotions thiab lwm yam kev npaj, ua si ntau lub luag haujlwm:
Gel Matrix: HEC feem ntau siv los ua ib qho matrix rau cov kua txiv, tshwj xeeb tshaj yog hauv kev xa tshuaj ntawm transdermal. Nws tuaj yeem muab cov tshuaj nyob hauv lub sijhawm ntawm daim tawv nqaij ntawm daim tawv nqaij, yog li kev txhim kho txoj kev ua tau zoo.
Viscosity thiab ruaj khov: lub viscosity ntawm HEC tuaj yeem txhim kho cov nplaum ntawm cov tawv nqaij npaj rau ntawm daim tawv nqaij los ntawm kev poob ntsej muag xws li kev sib txhuam lossis ntxuav. Ib qho ntxiv, HEC tuaj yeem txhim kho qhov ruaj khov ntawm cov cream thiab tshuaj pleev thiab tiv thaiv kev sib tsoo lossis ua kom nruj.
Roj nplua thiab moisturizer: HEC muaj zoo moisturizing zog thiab tuaj yeem pab ua kom cov tawv nqaij noo thiab yog li nws tseem siv nyob rau hauv cov khoom siv noo noo thiab lwm yam khoom tu cov tawv nqaij.
2.3 daim ntawv thov hauv Ophthalmic npaj
Daim ntawv thov ntawm HEC hauv OPHThalmic npaj yog mas los cuam tshuam hauv nws lub luag haujlwm ua cov nplaum thiab roj nplua nyeem:
Ophhalmic Gels thiab qhov muag poob: HEC tuaj yeem siv ua cov nplaum rau kev pib siv lub sijhawm ntawm cov tshuaj thiab cov tshuaj thiab paub meej ntxiv cov tshuaj ntxiv. Nyob rau tib lub sijhawm, nws viscosity kuj tseem tuaj yeem tiv thaiv qhov muag poob los ntawm kev poob nrawm thiab nce lub sijhawm ua haujlwm.
Lubrication: HEC muaj cov dej khov kho thiab tuaj yeem muab cov khoom siv lubrication zoo thiab tuaj yeem muab cov tshuaj txuas ntxiv rau hauv kev kho mob ntawm ophthalmic kab mob xws li qhuav qhov muag tsis xis nyob.
2.4 Daim ntawv thov hauv kev txhaj tshuaj npaj
HEC CAC kuj tseem siv tau rau hauv kev npaj txhaj tshuaj tshuaj txhaj tshuaj, tshwj xeeb tshaj yog nyob rau hauv kev txhaj tshuaj ntev thiab kev tso tawm-tso tawm. Cov haujlwm tseem ceeb ntawm HEC hauv cov kev npaj no suav nrog:
Thickener thiab stabilizer: hauv kev txhaj tshuaj,Tus patuaj yeem nce viscosity ntawm kev daws teeb meem, qeeb kev txhaj tshuaj ceev ntawm cov tshuaj, thiab txhim kho kev ruaj ntseg ntawm cov tshuaj.
Kev tswj cov tshuaj tso tawm: Raws li ib qho ntawm cov tshuaj muaj kev tawm hauv cov tshuaj, HEC tuaj yeem tswj hwm cov txheej gel tom qab txhaj tshuaj, yog li ua tiav lub hom phiaj ntawm kev kho mob ntev.
3. Lub Luag Haujlwm ntawm HEC hauv kev siv tshuaj tiv thaiv cov tshuaj
Nrog rau kev txhim kho cov kws tshuaj, HEC tau siv dav hauv ntau cov kev siv tshuaj, tshwj xeeb tshaj yog nyob hauv ib thaj chaw Nano-tshuaj, microshire, thiab cov cab kuj tso tawm. HEC tuaj yeem ua ke nrog ntau yam tshuaj cov tshuaj muaj tshuaj los ua cov khoom ruaj khov ua kom muaj cov tshuaj tso tawm kom meej thiab muaj txiaj ntsig zoo.
Nano tshuaj cov cab hlau: HEC tuaj yeem siv ua cov stabilizer rau cov neeg muaj tshuaj khib nyiab los tiv thaiv kev sib sau ua ke thiab nce cov khoom siv roj ntsha thiab nce cov tshuaj.
Jearchpheres thiab hais: HEC tuaj yeem siv los npaj cov tsom iav thiab cov nqa tshuaj yeeb hauv lub cev thiab txhim kho cov tshuaj.
Raws li cov tshuaj multifunctional thiab kev zam tau zoo, txhawj xeeb ®ec muaj cov kev cia siab thov kev npaj. Nrog kev txhim kho kev txuas ntxiv ntawm cov tshuaj thev naus laus zis, HEC ua tau txoj haujlwm tseem ceeb hauv kev tswj hwm kev tso tshuaj, kev tswj hwm hauv zos, kev xa tawm sai sai. Nws zoo biocompatibilibility, kho viscosity thiab ruaj khov ua rau nws irreplaceable hauv thaj teb tshuaj. Yav tom ntej, nrog kev kawm tob ntawm HEC, nws daim ntawv thov hauv kev npaj khoom lag luam yuav muaj ntau thiab sib txawv.
Lub Sijhawm Post: Dec-28-2024