Kev nyab xeeb ntawm HPMC hauv cov khoom noj ntxiv

1. Txheej txheem cej luam ntawm HPMC

HPMC (HydroxyPropyyl methylcellulose) yog lub cellulose derivative tau los ntawm kev hloov kho tshuaj lom neeg. Nws yog tau los ntawm ntuj cog cellulose los ntawm kev siv tshuaj lom neeg xws li methylation thiab hydroxyprodation. HPMC muaj cov dej ua kom zoo, viscosity hloov, ua yeeb yaj kiab, yog li nws tau siv cov tshuaj pleev ib ce, yog li cov tshuaj pleev ib ce, yog li cov tshuaj pleev ib ce, ua cov tshuaj pleev ib ce, khov kho thiab tus neeg sawv cev.

In the food industry, HPMC is often used as a thickener, gelling agent, humectant, emulsifier and stabilizer. Nws daim ntawv thov ntau hauv cov khoom noj suav nrog: ncuav, ncuav, khoom qab zib, khaub noom, khoom noj, khoom noj thiab cov zaub mov noj qab haus huv. Ib qho laj thawj tseem ceeb rau nws qhov kev txhawj xeeb ®

2. Kev soj ntsuam kev nyab xeeb ntawm HPMC

HPMC tau raug lees paub thiab pom zoo los ntawm ntau lub teb chaws thiab thoob ntiaj teb cov chaw muaj kev nyab xeeb zaub mov muaj kev tswj hwm cov chaw ua khoom noj ntxiv. Nws txoj kev nyab xeeb yog feem ntau ntsuas los ntawm cov hauv qab no:

Kev kawm toxicology

Raws li kev ua yeeb yam ntawm cellulose, HPMC yog raws ntawm cov nroj tsuag cellulose thiab muaj cov tshuaj lom tsawg. Raws li cov kev tshawb fawb toxicology ntau, kev siv HPMC hauv cov zaub mov tsis tuaj yeem qhia pom mob siab lossis mob ntev. Feem ntau cov kev tshawb fawb tau qhia hais tias HPMC muaj cov biocompatibility zoo thiab yuav tsis ua rau pom kev lom zem ntawm cov neeg muaj kuab lom. Piv txwv li, cov txiaj ntsig ntawm kev mob siab rau ntawm HPMC ntawm cov nas ua rau cov tshuaj tiv thaiv kev noj haus muaj ntau yam ntawm cov zaub mov noj kom zoo).

Kev nkag thiab Adis (Siv Tau Txhua Hnub Tso Cai Txhua Hnub)

Raws li kev ntsuam xyuas cov kws tshaj lij zaub mov, kev siv tau txhua hnub (ADI) ntawm HPMC yuav tsis ua phem rau tib neeg kev noj qab haus huv nyob rau hauv ib qho kev siv kom muaj. Tus Kws Tshaj Lij Thoob Ntiaj Teb ntawm Pab Neeg Ua Si (Jecfa) thiab lwm cov chaw nyab xeeb ntawm HPMC ua zaub mov ntxiv thiab tsim cov kev txwv tsim nyog rau nws. Hauv nws daim ntawv ntsuam xyuas nws, Jecfa tau taw qhia tias HPMC tsis tau ua rau muaj cov khoom noj muaj txiaj ntsig hauv qab ntawm cov nqi ADI, yog li cov neeg siv khoom tsis tas yuav txhawj txog nws cov peev xwm kev txaus ntshai.

Kev ua xua thiab cov kev tsis zoo

Raws li cov khoom siv ntuj, HPMC muaj qhov tsis muaj kev fab tshuaj tsis haum. Cov neeg feem coob tsis muaj kev fab tshuaj rau HPMC. Txawm li cas los xij, qee tus neeg nkag siab yuav tshwm sim ua tsis taus pa xws li ua pa thiab ua tsis taus pa thaum noj zaub HPMC. Xws li kev tawm tsam feem ntau tsis tshua muaj. Yog tias tsis xis nyob, nws raug nquahu kom tsis txhob noj cov zaub mov uas muaj HPMC thiab nrhiav cov lus qhia ntawm tus kws kho mob tshaj lij.

Kev siv ntev ntev thiab kev mob plab hnyuv

Raws li lub siab-molecular compound, ntxhov siab ® Yog li ntawd, nruab nrab ntawm HPMC yuav muaj qee yam zoo rau txoj hnyuv huv. Piv txwv li, qee cov kev tshawb fawb tau pom tias HPMC muaj qee lub peev xwm hauv kev txhim kho cov hlab ntsha plab hnyuv ntxig thiab hloov chaw. Txawm li cas los xij, ntau dhau ntawm HPMC yuav ua rau mob plab zom mov, plab zom mov, raws plab thiab lwm yam tsos mob ntawm kev tswj tau.

3. Kev Pom Zoo ntawm HPMC nyob rau txawv teb chaws

Phiaj suav

Hauv Suav teb, HPMC yog teev raws li kev tso cai zaub mov ntxiv, cov khoom siv, thiab lwm yam. Xws li kev siv HPMC tau pom zoo siv Hauv cov zaub mov tshwj xeeb thiab muaj kev txwv feem txwv.

European Union

Hauv European Union, HPMC tseem raug lees paub tias yog cov zaub mov muaj kev nyab xeeb ntxiv, suav cov e464. Raws li kev ntsuam xyuas cov lus qhia txog kev nyab xeeb hauv European (EFSA), HPMC muaj kev nyab xeeb nyob rau hauv kev siv thiab tsis qhia txog kev tsis zoo rau tib neeg kev noj qab haus huv.

Tebchaws Asmeskas

Tebchaws Asmeskas FDA teev HPMC ua "feem ntau lees paub tias muaj kev nyab xeeb" (gras) yeeb tshuaj thiab tso cai rau nws siv hauv cov zaub mov. FDA tsis teeb tsa kev txwv nruj rau kev siv HPMC, thiab tsuas yog ntsuas nws kev nyab xeeb raws li kev tshawb fawb hauv kev siv.

Raws li cov zaub mov ntxiv,HPMC tau pom zoo nyob hauv ntau lub tebchaws thiab cheeb tsam thoob ntiaj teb thiab tau txiav txim siab muaj kev nyab xeeb hauv kev siv tau siv ntau yam. Nws txoj kev nyab xeeb tau txheeb xyuas los ntawm ntau cov kev kawm txog kev sib tw toxicological thiab cov chaw kuajmov, thiab nws tsis tsim kev phom sij rau tib neeg kev noj qab haus huv. Txawm li cas los xij, zoo li txhua tus neeg noj khoom haus cov zaub mov noj ntxiv, hauv HPMC yuav tsum ua raws li txoj ntsiab cai ntawm kev siv tsim nyog thiab zam dhau. Cov tib neeg uas ua xua yuav tsum ceev faj thaum noj zaub mov uas muaj HPMC los txo cov kev tshwm sim uas muaj kev nyuaj siab.

HPMC yog siv dav dav thiab muaj kev nyab xeeb ntxiv hauv kev lag luam khoom noj khoom haus, kev pheej hmoo me rau kev noj qab haus huv. Nrog kev nce qib ntawm kev tshawb fawb thiab kev tshawb fawb thiab kev saib xyuas ntawm kev txhawj xeeb ®hpmc kuj yuav muaj kev ntxhov siab ntau ntxiv rau yav tom ntej kom ntseeg tau tias nws muaj kev nyab xeeb.