HydroxyPropyyl Methylcellulose (HPMC)yog tsis-ionic, dej-soluble cellulose sib xyaw ether. Cov tsos yog dawb rau me ntsis hmoov daj los yog cov khoom siv granular, tsis muaj ntxhiab, thiab yaj tsis khov, pob tshab thiab cov tshuaj pleev xim. Ib qho ntawm cov khoom tseem ceeb tshaj plaws ntawm hydroxypropylulcellulose hauv daim ntawv thov yog tias nws nce viscosity ntawm cov kua. Cov nyhuv tuab yog nyob ntawm cov qib ntawm polymerization (dp) ntawm cov tshuaj ethoous nyob rau cov kua aqueous, tus nqi shear, thiab daws qhov ntsuas kub. Thiab lwm yam.
01
Kua hom HPMC aqueous
Feem ntau, kev ntxhov siab ntawm cov kua dej hauv shear flow tuaj yeem qhia raws li kev ua haujlwm ntawm tsuas yog tus nqi shear ƒ (γ), tsuav nws tsis yog lub sijhawm. Nyob ntawm daim foos ƒ (γ), kua tuaj yeem muab faib ua ntau hom, ua kua dej, pseudoplastic kua thiab bingham kua roj.
Cov neeg hais ua haujlwm ntawm cellulose tau muab faib ua ob pawg: ib qho tsis yog-ionic cellulose ether thiab lwm yam yog ionic cellulose ether. Rau cov rhuaology ntawm ob hom ntawm cov neeg hais lus hauv cellulose. SC NAKIC ລ... Ua cov kev kawm ua piv nrog cov kev kawm sib piv ntawm hydroxyethyl cellulose thiab sodium carboxymethyl cellulose cellulose kev daws teeb meem. Cov txiaj ntsig tau pom tias ob tus neeg tsis-ionic cellulose kev daws thiab ionic cellulose collets tau pseudoplastic. Ntws, piv txwv li tsis yog-Newtonian ntws, mus kom ze cov kua Newtonian nkaus xwb nyob rau ntau qhov ntau. Lub pseudoplastic ntawm hydroxypropyl cetal methylulose tov ua lub luag haujlwm tseem ceeb hauv kev thov. Piv txwv li, thaum siv rau hauv cov txheej txheem, vim yog cov kev daws teeb meem ntawm cov tshuaj uas poob qis, uas yog viscosity los ntawm cov xim xim, thiab kuj tseem ua rau kom muaj dej ntawm txheej Cov. Cov nyhuv loj heev; Thaum lub sijhawm so, lub viscosity ntawm kev daws teeb meem yog qhov loj, uas tiv thaiv kev tso nyiaj ntawm cov xim xim hauv txheej.
02
HPMC Viscire Test txoj kev
Qhov taw qhia tseem ceeb los ntsuas cov nyhuv tuab ntawm hydroxyprropyl methylculose yog qhov pom tau viscosity ntawm cov aqueous. Txoj kev ntsuas ntsuas ntawm pom tseeb viscosity feem ntau suav nrog hom phiaj viscosity, kev sib txawv viscosity txoj kev, kev poob pob viscosity homcosity.
qhov twg: yog lub meej viscosity, mpa s; K yog tus mus viscepus tas li; d yog qhov ntom ntawm cov kev daws teeb meem ntawm 20/20 ° C; t yog lub sij hawm rau kev daws kom dhau los ntawm sab qaum kev ntawm tus vislivus mus rau hauv qab Malcais, S; Lub sijhawm uas cov roj txheem txheem ntws los ntawm cov visliver raug ntsuas.
Txawm li cas los xij, txoj kev ntsuas ntsuas los ntawm cov volillus muaj teeb meem ntau dua. Cov viscosities ntawm ntauNeeg muaj neeg ua haujlwmYog qhov nyuaj los tshawb xyuas kom siv cov vis discometer vim tias cov kev daws teeb meem muaj cov teeb meem insoluble uas tsuas yog kuaj pom thaum tus visliv raug kaw. Yog li ntawd, feem ntau cov tuam ntxhab siv cov kev sib hloov mus rau kev tswj hwm qhov zoo ntawm hydroxypropyf methylulose. Brookfield Viscielders feem ntau siv nyob rau txawv teb chaws teb chaws, thiab NDJ cov neeg tuaj saib xyuas yog siv nyob rau hauv Suav teb.
03
Zom cov ntsiab lus ntawm HPMC viscosity
3.1 Kev sib raug zoo nrog kev sib sau ua ke
Thaum lwm qhov kev txwv tsis hloov pauv, lub viscosity ntawm hydroxyprropylulose kev daws teeb meem (dp) lossis nce nrog nce qib ntawm polymerization. Cov nyhuv no yog tshaj tawm txog cov xwm txheej qis ntawm polymerization tshaj li ntawm cov kev kawm qib siab polymerization.
3.2 Kev sib raug zoo ntawm viscosity thiab conferration
Lub viscosity ntawm hydroxypropyf methylculose nce nrog kev nce ntawm cov kev xav ntawm cov khoom lag luam hauv cov kua aqueous. Txawm tias muaj qhov hloov me me hloov yuav ua rau muaj kev hloov loj hauv viscosity. Nrog lub nominal viscosity ntawm hydroxypropylulcelleculose cov nyhuv ntawm kev hloov ntawm kev daws teeb meem ntawm kev daws teeb meem yog ntau dua thiab ntau pom tseeb.
3.3 Kev sib raug zoo ntawm viscosity thiab shear tus nqi
HydroxyPropy muag methylcellulose aqueous kua txiv muaj cov cuab yeej ntawm shear thinning. HydroxyPropylencellulose ntawm sib txawv nominal viscosity yog npaj rau hauv 2% kev daws teeb meem, thiab nws cov viscosity ntawm txawv shear tus nqi yog ntsuas feem ntau. Cov txiaj ntsig tau yog raws li hauv qab no raws li qhia hauv daim duab. Ntawm qhov tsawg shear tus nqi, lub viscosity ntawm hydroxypropyl methylulose tov tsis hloov pauv ntau. Nrog rau kev nce ntawm shear tus nqi, lub viscosity ntawm hydroxypropylulose kev daws teeb meem tsawg dua, thaum kev daws nrog cov viscosity qis tsis txo obvosity.
3.4 Kev sib raug zoo ntawm viscosity thiab kub
Lub viscosity ntawm hydroxypropyyl methylulose tov yog qhov cuam tshuam zoo heev los ntawm qhov kub. Raws li qhov kub nce ntxiv, lub viscosity ntawm kev daws teeb meem tsawg. Raws li muaj nyob hauv daim duab, nws tau npaj ua cov tshuaj aqueous nrog lub tswv yim ntawm 2%, thiab kev hloov pauv ntawm lub viscosity nrog kev nce ntawm qhov kub yog ntsuas.
3.5 Lwm yam cuam tshuam
Lub viscosity ntawm kev daws teeb meem aydroxyprropyl kuj tseem cuam tshuam los ntawm cov kev sib ntxiv hauv kev daws teeb meem, thiab cov nqi microbial. Feem ntau, nyob rau hauv thiaj li yuav tau txais zoo viscosity kev ua tau zoo lossis txo cov nqi ntawm cov av nplaum, cov hmoov av, rau cov kua txiv ntoo ntawm hydroxypropylencellulose. , thiab electrolytes xws li chloride, bromide, phosphate, nitrate, thiab lwm yam. Cov tshuaj ntxiv no yuav tsis tsuas yog cuam tshuam rau cov hom phiaj viscoous ntawm cov kua aqueous, tab sis kuj tseem cuam tshuam lwm yam khoom ntawm hydroxypropylulose xws li dej khaws cia. , Sag tiv, thiab lwm yam.
Lub viscosity ntawm areous daws ntawm hydroxypropylulose yog yuav luag tsis cuam tshuam nrog cov kua qaub tsis muaj zog, thiab feem ntau yog nyob rau hauv thaj tsam ntawm 3 txog rau acid, phosphoric acid, phosphoric acid, phosphoric acid , boric acid, citric acid, etc. Txawm li cas los xij, muaj cov acc muaj zog yuav txo cov viscosity. Tab sis caustic dej qab zib, cov poov tshuaj hydroxide, kua qaub, thiab lwm yam. Cov nyhuv me me rau nws. Piv nrog lwm cov cellulose neeg muaj kev pab,HydroxyPropyyl MethylcelluloseCov tshuaj aqueous muaj cov tshuaj tiv thaiv zoo, yog feem ntau tsis muaj kev sib tw yog feem ntau yooj yim tshaj plaws los ntawm cov kab mob me, ua rau muaj kev cuam tshuam Nyob rau hauv kev cuam tshuam ntawm cellulose ether molecules thiab saw saw ceev. Cov kev ua tau zoo yog qhov pom tseeb viscosity ntawm cov tshuaj aqueous tsawg zuj zus. Yog tias nws yog ib qho tsim nyog los khaws cov tshuaj ahox ntawm hydroxypropylulose rau lub sijhawm ntev, nws raug nquahu kom ntxiv cov tshuaj tiv thaiv kab mob kom cov viscosity tsis tau hloov pauv. Thaum xaiv cov tshuaj tiv thaiv fungal, cov tshuaj tiv thaiv cov tshuaj lom neeg, koj yuav tsum tau them nyiaj rau tib neeg lub cev, thiab tsis muaj ntxhiab tsw qab, koj yuav tsum them nyiaj thiab lwm yam khoom. tuaj yeem ua txoj haujlwm sib luag.
Lub Sijhawm Post: Apr-28-2024