Dab tsi yog rheological cov khoom ntawm HPMC?

Dab tsi yog rheological cov yam ntxwv ntawmHPMC?

HydroxyPropyyl methylcellose (HPMC) yog cov tshuaj polymer ntau ntxiv, tsim kho, thiab tshuaj pleev ib ce, feem ntau vim yog nws cov khoom siv hluav taws xob tshwj xeeb. Rheology yog txoj kev kawm txog kev ntws thiab deformation ntawm cov ntaub ntawv, thiab nkag siab txog cov khoom ntawm HPMC yog qhov ua tau zoo rau nws txoj kev ua tau zoo rau cov ntawv thov sib txawv.

Viscosity: HPMC cov khoom ua pov thawj pseudopastic lossis shear-thinning tus cwj pwm, lub ntsiab lus nws viscosity txo qis nrog nce shear tus nqi. Cov cuab yeej no yog qhov tseem ceeb hauv cov ntawv thov xws li cov tshuaj ntsiav tshuaj, qhov chaw uas nws tso cai rau kev tso dej yooj yim, kis, thiab daim ntawv thov. Viscosity tuaj yeem ua kom haum los ntawm kev hloov kho cov degree ntawm kev hloov pauv (DS) thiab hnyav hnyav ntawm HPMC.

Thixotropy yog hais txog cov kev hloov pauv tau yooj yim los ntawm kev ua tau zoo los ntawm qee cov ntaub ntawv nyob rau qee cov ntaub ntawv hauv qab kev nyuaj siab. HPMC cov kua muag tsim ntawm cov so tuaj yeem tsoo hauv qab shear thiab rov qab ua lawv cov qauv gel thaum cov kev ntxhov siab raug tshem tawm. Cov cuab yeej no yog qhov zoo hauv kev siv zoo li cov xim zoo li xim, qhov uas nws tiv thaiv sagging thaum lub sijhawm thov ib zaug tab sis ua kom tiav cov txheej ua tiav ib zaug thov.

Hydration: HPMC yog hygroscopic thiab tuaj yeem nqus dej, ua rau o thiab nce viscosity. Cov degree ntawm kev tswj cov dej nyob ntawm yam xws li qhov kub, pH, thiab ionic zog ntawm nruab nrab nruab nrab. Cov txheej txheem txheej ua lub luag haujlwm tseem ceeb hauv kev tswj cov tshuaj tso tawm los ntawm cov kws ua tshuaj thiab tswj cov dej noo hauv cov khoom noj.

Kub rhiab:HPMCCov kev daws teeb meem kub-nyob-nyob viscosity, nrog viscosity txo raws li kub nce ntxiv. Txawm li cas los xij, tus cwj pwm no sib txawv raws li cov xwm txheej xws li polymer concentration thiab kev daws Ph. Kub rhiab yog qhov tseem ceeb hauv cov ntawv thov xws li cov khoom siv, uas cuam tshuam rau kev ua haujlwm thiab sijhawm sijhawm ua haujlwm.

Ntsev rhiab tau: HPMC cov kev daws teeb meem yuav nthuav tawm cov rhiab rau cov ntsev, nrog cov salts ua rau viscosity ntxiv. Qhov tshwm sim no yog ntaus nqi rau cov kev sib cuam tshuam ntawm HPMC lwg me thiab ions hauv kev daws teeb meem. Ntsev rhiab tau yog qhov tseem ceeb hauv cov kws tshuaj tsim thiab cov khoom lag luam khoom noj yuav tsum tau ua tib zoo tswj hwm.

Kev vam khom Shear tus nqi: Lub zog rheological ntawm HPMC cov kev daws teeb meem yog qhov vam khom rau ntawm cov kab mob shear. Ntawm cov nqi shear tsawg, viscosity yog siab dua rau nce molecular entanglement, whereas ntawm high shear cov nqi, viscosity txo vim muaj shear thinning. Nkag siab shear tus nqi yuav tsum vam khom yog qhov tseem ceeb rau kev ua cov kev pabcuam hauv ntau yam kev siv.

Kev ncua kev ncua: HPMC tuaj yeem ua raws li kev ncua tus neeg sawv cev rau cov khoom siv hauv cov kua ua kua vim nws cov khoom siv ua kom ruaj khov thiab ruaj khov. Nws pab tiv thaiv kev tawm ntawm cov khoom khov kho, kom muaj kev faib tawm cov khoom sib txuas lus thiab sib xws hauv cov khoom lag luam xws li cov xim tha xim, cov nplaum, thiab kev ncua ntawv.

Gel tsim:HPMCtuaj yeem tsim cov gels ntawm qhov siab siab lossis nyob hauv lub xub ntiag ntawm cov neeg sawv cev sib cav xws li cations sib npaug. Cov khoom plig no nthuav qhia cov khoom vepcoelastic muaj thiab siv hauv kev thov xws li tswj cov tshuaj tso tawm, uas tau txhawb nqa cov khoom xyaw uas yuav tsum tau ua.

Lub zog rheological ntawm HPMC, suav nrog viscosity, thixotropy, kev ncua tawm, ua si qhov kev sib raug zoo hauv kev txiav txim siab nws cov kev ua tau zoo hauv kev lag luam. Nkag siab thiab kev tswj hwm cov khoom no yog qhov tseem ceeb rau kev ua haujlwm zoo rau kev tsim thiab cov khoom HPMC.