HydroxyPropyyl Metylcellulose (HPMC) yog cov tshuaj polymer ntau yam hauv ntau yam kev lag luam hauv ntau yam kev lag luam, khoom noj khoom haus, tsim thiab tshuaj pleev ib ce. Cov ntaub ntawv raw tseem siv los ua ke HPMC yog cellulose thiab propylene oxide.
1. Cellulose: Lub hauv paus ntawm HPMC
1.1 Txheej txheem cej luam ntawm cellulose
Cellulose yog ib tug ua carbohydrate uas yog cov txheej txheem tseem ceeb ntawm ntsuab nroj tsuag phab ntsa. Nws muaj cov kab txuas ntawm cov piam thaj molecules sib txuas ua ke los ntawm β-1,4-glycosidic bonds. Qhov ntau ntawm cov pawg hydroxyl hauv cellulose ua rau nws pib cov khoom pib rau cov synthesis ntawm ntau cov cellulose derivatives, suav nrog HPMC.
1.2 cellulose muaj
Cellulose tuaj yeem muab tau los ntawm cov nroj tsuag sib txawv, xws li ntoo pulp, cov ntoo paj rwb, lossis lwm cov nroj tsuag fibrous. Ntoo pulp yog ib qho tshwm sim vim yog nws cov kev nplua mais, tus nqi-ua hauj lwm zoo, thiab muaj kev ruaj ntseg. Qhov kev rho tawm ntawm cellulose feem ntau cuam tshuam nrog rhuav tshem cov nroj tsuag fibers los ntawm cov txheej txheem ntawm cov neeg kho tshuab thiab tshuaj lom neeg.
1.3 purity thiab yam ntxwv
Qhov zoo thiab huv ntawm cellulose yog qhov tseem ceeb hauv kev txiav txim siab cov yam ntxwv ntawm HPMC kawg cov khoom lag luam. High-purity cellulose kom paub tias HPMC yog tsim nrog cov khoom xws li xws li viscamity, solubility thiab thermal stability.
2. Propylene Oxide: Taw qhia ntawm HydroxyPropyl
2.1 Taw qhia rau Propylene Oxide
Propylene oxide (PO) yog cov organic sib xyaw nrog cov tshuaj c3h6o. Nws yog EPOXIDE, txhais tau tias nws muaj cov pa Axygen atom Bonded rau ob lub tswv yim carbon ib sab. Propylene oxide yog cov khoom siv tseem ceeb rau cov synthesis ntawm hydroxyprropyl cellulose, uas yog ib qho kev sib tshuam ntawm HPMC.
2.2 HydroxyproreSylation Txheej Txheem
Cov txheej txheem hydroxyprropation muaj cov tshuaj tiv thaiv ntawm cov tshuaj pleev nrog propylene oxide los qhia cov pab pawg hydroxyproprox. Qhov kev tawm tsam no feem ntau tau nqa tawm hauv lub xub ntiag ntawm cov catalyst yooj yim. Hydroxypropyl pawg neeg cog lus txhim kho solubility thiab lwm yam kev tsim nyog rau cellulose, ua rau kev tsim ntawm hydroxyprropyl cellulose.
3. Methylation: Ntxiv Metyl pawg
3.1 Cov Txheej Txheem Methylation
Tom qab hydroxypropy, cov kauj ruam tom ntej hauv HPMC synthesis yog methylation. Cov txheej txheem cuam tshuam nrog kev qhia ntawm methyl pawg rau hauv lub cellulose caj qaum. Methyl Chloride yog cov siv reagent rau qhov kev tawm tsam no. Cov qib kawm ntawm methylation cuam tshuam rau cov khoom ntawm cov khoom HPM thib kawg, suav nrog nws cov viscosity thiab tus cwj pwm gel.
3.2 Qib ntawm Hloov Chaw
Cov degree ntawm kev hloov pauv (DS) yog qhov tseem ceeb rau ntau qhov chaw ntawm cov neeg hloov chaw (methyl thiab hydroxypropyl) ib chav tsev ib qho ntawm lub cellulogrose chart. Cov txheej txheem tsim khoom yog ua tib zoo tswj kom ua tiav cov khoom lag luam HPMC.
4. Kev ua kom huv thiab tswj tau zoo
4.1 Tshem Tawm Ntawm Cov Khoom
Qhov synthesis ntawm HPMC yuav ua rau muaj kev tsim cov khoom ntawm cov khoom lag luam xws li cov ntsev lossis siv cov tshuaj reagents. Cov kauj ruam lim neeg ua xws li kev ntxuav thiab pom tau siv tshem cov impurities thiab nce kev coj dawb huv ntawm cov khoom kawg.
4.2 Tswjhwm Ntsuas Kev Ntsuas Zoo
Nruj me ntsis kev ntsuas tau ua tiav thoob plaws kev tsim cov txheej txheem los ua kom muaj xwm yeem thiab zoo ntawm HPMC. Kev ntsuas kev tshuaj xyuas xws li spectroscopy, chromatography thiab rhelology yog siv los soj ntsuam tsis xws li molecular hnyav, qib siab hloov chaw thiab hloov chaw.
5. Cov yam ntxwv ntawm hydroxypropyl methylcellose (HPMC)
5.1 Cov Khoom Siv Lub Cev
HPMC yog ib qho dawb kom tawm-dawb, tsw ntxhiab nrog cov yeeb yaj kiab zoo heev-ua cov khoom. Nws yog hygroscopic thiab yooj yim tsim lub pob tshab gel thaum dispersed hauv dej. Lub solubility ntawm HPMC yog nyob ntawm cov qib hloov pauv thiab cuam tshuam los ntawm cov yam ntxwv xws li qhov ntsuas kub xws li ntsuas kub thiab Ph.
5.2 Tshuaj Lom Zem
Tus qauv tshuaj ntawm HPMC muaj cov cellulose caj qaum nrog hydroxypropyl thiab methyl hloov. Qhov sib piv ntawm cov kev hloov no, pom nyob rau hauv cov degree hloov chaw, txiav txim siab cov qauv tshuaj tag nrho thiab yog li cov khoom ntawm HPMC.
5.3 Viscosity thiab rheological khoom
HPMC muaj nyob rau hauv ntau qib nrog cov viscosity sib txawv. Lub viscos ntawm HPMC cov kev daws teeb meem yog qhov tseem ceeb hauv cov ntaub ntawv xws li cov tshuaj tso tawm, qhov uas nws cuam tshuam rau kev ua haujlwm ntawm cov neeg nplua nuj thiab cov pases.
5.4 Zaj duab xis-ua thiab thickening cov khoom
HPMC tau dav siv raws li zaj duab xis yav dhau los hauv cov txheej txheem pleev tshuaj yeeb thiab raws li tus neeg sawv cev tuab ntawm ntau yam. Nws cov kev ua yeeb yaj kiab ua yeeb yaj kiab ua rau nws muaj txiaj ntsig zoo hauv kev txhim kho cov tshuaj ntsuas cov tshuaj txiav tawm thiab ruaj khov ntawm ntau cov khoom lag luam.
6. Daim ntawv thov ntawm hydroxypropyl methylcellose
6.1 Kev Lag Luam Hluav Taws Xob
Hauv kev lag luam kws tshuaj, HPMC yog siv los tsim cov ntaub ntawv foos rau cov ncauj hluav taws xob xws li cov ntsiav tshuaj thiab cov ntsiav tshuaj. Nws yog ib qho siv tau siv los ua cov phau ntawv, ua txhaum thiab zaj duab xis txheej tus neeg sawv cev. Cov tswj hwm-tso tawm ntawm HPMC pab txhawb nws daim ntawv thov hauv kev tawm tswv yim-tso tawm.
6.2 Kev Tsim Kho Kev Tsim Kho
Hauv kev ua haujlwm hauv kev ua haujlwm, HPMC yog siv los ua dej tuav tus neeg sawv cev, thickener thiab adhesive nyob rau hauv cov cement-raws cov khoom. Nws txhim kho cov haujlwm ntawm lub tshuaj khib, tiv thaiv sagging hauv cov ntawv thov ntsug, thiab txhim kho qhov kev ua tau zoo ntawm lub tsev.
6.3 Kev lag luam khoom noj khoom haus
HPMC yog siv nyob rau hauv kev lag luam khoom noj ua cov tuab, stabilizer thiab emulsifier. Nws lub peev xwm los ua cov tshuaj pleev ntawm cov tshuaj qis ua nws haum rau ntau cov ntawv thov, suav nrog cov kua ntses, hnav khaub ncaws, hnav thiab cov khoom qab zib.
6.4 Tshuaj pleev ib ce thiab cov khoom siv saib xyuas tus kheej
Hauv cov tshuaj pleev ib ce thiab cov khoom siv saib xyuas tus kheej, HPMC, HPMC tau pom muaj ntau yam ntawm cov tshuaj pleev suav nrog cov cream, tshuaj thiab tsuaj zawv. Nws pab txhim kho cov kev ntxhib los mos, ruaj khov thiab tag nrho kev ua tau zoo ntawm cov khoom no.
6.5 Lwm Yam Kev Lag Luam
HPMC cov versatility txuas rau lwm cov kev lag luam, suav nrog cov ntawv, xim thiab cov nplaum, qhov uas nws tuaj yeem siv los ua cov tshuaj rheology, dej rov ua tus neeg saib xyuas thiab cov tuab tuab.
7. Xaus
Hydroxyprropyloosylcethylcellose yog ib qho polymer ntau yam nrog ntau daim ntawv thov. Nws cov synthesis siv cellulose thiab propylene oxide ua cov ntaub ntawv raw loj, thiab lub cellulose tau hloov kho los ntawm hydroxyprropation thiab methylation cov txheej txheem. Tswj kev tswj hwm cov khoom siv thiab cov kev tawm tsam tuaj yeem tsim HPMC nrog cov khoom lag luam xav tau tshwj xeeb. Yog li ntawd, HPMC ua si lub luag haujlwm tseem ceeb hauv kev txhim kho kev ua tau zoo thiab kev ua haujlwm ntawm cov khoom hla kev lag luam. Kev tshawb xyuas cov ntawv thov txuas ntxiv ntawm cov ntawv thov tshiab thiab kev txhim kho ntawm kev tsim cov txheej txheem pab HPMC txuas ntxiv mus ua lag luam tseem ceeb hauv kev ua lag luam thoob ntiaj teb.
Lub Sijhawm Post: Dec-28-2023