Hydroxypropylencellulose (HPMC) yog lub cellulose derivative feem ntau siv nyob rau hauv ntau yam kev lag luam, suav nrog cov tshuaj, kev tsim kho thiab khoom noj. Nws cov viscosity tuaj yeem sib txawv nyob ntawm qhov xwm txheej xws li nws cov kev hnyav molecular, qib siab hloov chaw, thiab kev daws teeb meem.
Taw qhia rau hydroxyPropyyl Metthylcellulose (HPMC)
HydroxyPropyyl Metylcellulose yog ib nrab hluavtaws polymer tau los ntawm kev hloov tshuaj lom neeg ntawm cellulose. Vim nws cov khoom tshwj xeeb, nws tau siv dav siv los ua cov tuab dua, tus neeg sawv cev ntawm tus txiv neej, zaj duab xis yav tas los thiab stabilizer nyob rau hauv ntau yam kev siv.
Molecular qauv thiab muaj pes tsawg leeg
HPMC muaj cov cellulose caj qaum nrog hydroxypropyl thiab methoxy hloov chaw. Cov degree ntawm kev hloov pauv (DS) yog hais txog qhov nruab nrab ntawm cov neeg nyob nruab nrab ntawm ib chav ntawm lub cev hauv lub cellulose saw. Tus nqi tshwj xeeb DS cuam tshuam rau lub cev thiab tshuaj lom neeg ntawm HPMC.
HPMC viscosity
Viscosity yog ib qho kev ntsuas tseem ceeb rau HPMC, tshwj xeeb tshaj yog hauv cov ntawv thov uas siv nws cov khoom siv tuab thiab ua kom zoo nkauj.
Lub viscosity ntawm HPMC cov kev daws teeb meem cuam tshuam los ntawm ntau yam:
1. Molecular hnyav
Qhov hnyav molecular ntawm HPMC cuam tshuam nws viscosity. Feem ntau, siab dua molecular hnyav HPMCs zoo li tsim cov kev tawm tsam muaj kuab. Muaj cov qhab nia sib txawv ntawm HPMC ntawm kev ua lag luam, txhua tus nrog nws tus kheej tsim cov mis nyuj hnyav ntau.
2. Qib ntawm Hloov Chaw (DS)
Lub DS qhov tseem ceeb ntawm hydroxypropyl cuam tshuam rau solubility thiab viscosity ntawm HPMC. Cov DS cov nyiaj ntau dua feem ntau ua rau cov dej solubility nce ntxiv thiab cov kev daws teeb meem tuab.
3. Lub siab
Cov concentration ntawm HPMC hauv kev daws yog qhov tseem ceeb rau viscosity. Raws li cov concentration nce, viscosity feem ntau nce. Qhov kev sib raug zoo no feem ntau tau piav qhia los ntawm kev sib koom ua keyeger-kev ua noj.
4. Kub
Qhov kub kuj cuam tshuam cov viscosity ntawm HPMC cov kev daws teeb meem. Feem ntau hais lus, viscosity zuj zus li kub nce.
Chaw thov
Kws Tshuaj: HPMC yog feem ntau siv nyob rau hauv cov tshuaj, suav nrog cov ntsiav tshuaj thiab cov kev daws teeb meem ophthalmic, qhov chaw tswj tau yog qhov tseem ceeb.
Kev tsim kho: Hauv kev tsim kho kev tsim kho, HPMC yog siv los ua cov ntaub tuab hauv cov khoom noj kom zoo kom txhim kho cov haujlwm thiab dej khaws cia.
Kev Lag Luam Khoom Noj: HPMC yog siv los ua cov tuab, stabilizer thiab emulsifier hauv cov ntawv thov noj.
Lub viscosity ntawm hydroxypropylencellulose yog cov cuab yeej nyuaj uas cuam tshuam los ntawm ntau yam xws li hnyav molecular, degree ntawm hloov chaw, kev pom zoo thiab kub. Cov qhab nia sib txawv ntawm HPMC yog muaj los muab cov ntawv thov tshwj xeeb, thiab cov tuam ntxhab muab cov ntaub ntawv qhia txog txhua qib ntawm txhua qhov xwm txheej. Cov kws tshawb fawb thiab cov kws sau ua ke yuav tsum xav txog cov yam ntxwv los txiav cov khoom ntawm HPMC kom tau raws li lawv cov ntawv thov npaj.
Lub Sijhawm Post: Jan-20-2024