Eutters Cellugul maka mwepụta ọgwụ ọjọọ na sistemụ matrik hydrophic

Ekwo Ethers Cellugul, ọkachasịHydroxypylththththththylcelllose (hpmc), bụ ebe niile na-arụ ọrụ na ọgwụ maka ọgwụ maka iwepụta ọgwụ na-achịkwa nke ọgwụ na sistemụ mattrix. Ntọhapụ ọgwụ a na-achịkwa dị oke mkpa maka njikarịcha ọgwụgwọ, belata nsonaazụ, ma mee ka anyị nwee ndidi. Nke a bụ otu atters cellers na-arụ ọrụ na sistemụ matrik hydrophic maka ịhapụ ọgwụ ọgwụ na-achịkwa:

1. Sistemu Matrix:

• Nkọwa: Sistem hydrophic bụ sistemụ nnyefe ọgwụ nke ihe na-emepụta ọgwụ (API) na-agbasa ma ọ bụ tinye ya na polymer polymer polymer.
• Ebumnuche: Matriks na-achịkwa mwepụta ọgwụ site na ịbawanye mgbasa ya site na polymer.

2. Ọrụ nke Ethers (dịka, HPMC):

• Ngwongwo viscositis na Njirimara Gel:
  • A maara HPMC maka ike ya iji mepụta gels ma nwekwuo viscosity.
  • Na sistemụ matrix, Hpmc na-enye aka na-etolite Matriks Gelatinous nke na-emetụta ọgwụ ahụ.
• Ọdịdị hydrophilic:
  • HPMC bụ nnọọ hydrophilic, na-emekọrịta mmekọrịta ya na mmiri na eriri afọ.
• Na-achịkwa Ọzịza:
  • Mgbe ịkpọtụrụ mmiri gastric, matriks hydrophic na-aza, na -emepụta gel gburugburu ọgwụ.
• Ọgwụ Invesalation:
  • A na-eji ọgwụ gel eme ihe ma ọ bụ tinye ya.

3. Usoro nke ịhapụ:

• Mgbasa na Errosion:
  • Ntọhapụ ndị a na-achịkwa na-apụta site na ngwakọta nke mgbasa na usoro mburiri.
  • Mmiri na-abanye matrix, na-eduga na gel ọzịza, ọgwụ a na-aghọrọ ọrịa na gel oyi akwa.
• Ntọhapụ Zero-Nyefee:
  • Profaịlụ nke a na-achịkwa na-esochikarị kinetics kinetics, na-enye ọkwa na-agbanwe agbanwe na nke amụma ka oge na-aga.

4. Ihe ndị na-emetụta ọgwụ:

• Polymer ịta:
  • Nta nke hpmc na matriks na-emetụta ọnụego nke ịtọhapụ ọgwụ.
• Igo nke HPMC:
  • Enwere ike ịhọpụta akara mmụta dị iche iche nke HPMC nke nwere ike ịhọpụta profaịlụ nkeonwe.
• Ndọghachi aka ọgwụ:
  • Nkwado nke ọgwụ dị na matrix na-emetụta njiri mara ya.
• Matrix possity:
  • Ogo nke gel ọzịza na Matrix CromeSosis.

5

• Ndị na-eme biocom: athers cellususe bụ ihe ndị bibiri ma na-anabata nke ọma na eriri afọ.
• Enwere ike ịhọrọ usoro nke mkpụrụ osisi cellususe iji nweta profaịlụ nke achọrọ.
• Ikwụsi ike: evethers cellususe na-enye nkwụsi ike na sistemụ matrix, na-ejide ntọhapụ ọgwụ na-agbanwe agbanwe agbanwe agbanwe n'oge.

6. Ngwa:

• Ntinye ọgwụ ọnụ: A na-ejikarị sistemụ ọgwụ ukrix maka usoro ọgwụ ọgwụ, na-enye ya ma na-achịkwa ya.
• Ọnọdụ na-adịghị ala ala: Ezigbo maka ọgwụ ndị e ji na-adịghị ala ala ebe ịtọhapụ ọgwụ na-aga n'ihu bara uru.

7. Atụmatụ:

• Usoro nhazi: a ga-ahazi profaịlụ nke ọgwụ ị ga - eme nke ọma na ihe ọgwụgwọ ọgwụ ọgwụ.
• Nchịkọta Iwu: Evers Could nke eji na ọgwụ ga-eme ihe ga-eme ka usoro iwu.

Iji usoro celdigose na sistemụ matrik na-emepụta ihe ha dị mkpa na usoro ọgwụgwọ, na-enye usoro dị mma ma dị mma iji nweta ntọhapụ ọgwụ na-achịkwa.