Njirimara teknụzụ okpomọkụ dị elu maka hydroxypropyl methylcellulose

Hydroxypropyl methylcellulose (HPMC)bụ ihe dị mkpa kemịkalụ, nke a na-ejikarị eme ihe ụlọ, ọgwụ, nri na ubi ndị ọzọ. Karịsịa na ụlọ ọrụ ihe owuwu, a na-eji HPMC eme ihe n'ọtụtụ ebe n'ihi arụmọrụ ya dị mma. Teknụzụ okpomọkụ dị elu na-arụ ọrụ dị mkpa na mmepụta na ngwa nke HPMC.

1. Ọrụ nke teknụzụ okpomọkụ dị elu na HPMC

mmepụta Hydroxypropyl methylcellulose na-enweta site na usoro mmeghachi omume kemịkalụ dị ka alkalization na etherification nke cellulose eke. A na-ejikarị teknụzụ okpomọkụ dị elu mee ihe na mgbasa, ihicha na ịkpụzi nkebi nke usoro mmeghachi omume. Ọgwụgwọ okpomọkụ dị elu nwere ike ọ bụghị naanị mee ka ọnụ ọgụgụ mmeghachi omume dịkwuo elu, kamakwa melite ịdị ọcha na nkwụsi ike nke ngwaahịa ahụ.

Mmezi mmeghachi omume emelitere

N'okpuru ọnọdụ okpomọkụ dị elu, a na-emewanye mmeghachi omume nke cellulose na sodium hydroxide, nke na-akwalite mmeghachi omume hydroxypropyl na methyl n'ime mkpụrụ ndụ cellulose, si otú ahụ na-emewanye ogo nke nnọchi (DS) na ịdị n'otu nke HPMC.

Wepu adịghị ọcha

The elu okpomọkụ gburugburu nwere ike n'ụzọ dị irè wepụ site-ngwaahịa emepụta n'oge mmeghachi omume, dị ka unreacted alkali ngwọta na mgbaze, na melite ịdị ọcha nke HPMC.

Emelitere arụmọrụ ihicha

N'oge usoro ihicha okpomọkụ dị elu, mmiri nke HPMC na-ekpochapụ ngwa ngwa, na-ezere ngwaahịa ahụ site na agglomerating ma ọ bụ denaturing na obere okpomọkụ, na-eme ka nkwụsi ike na nchekwa nke ngwaahịa.

2. Mmetụta nke teknụzụ okpomọkụ dị elu na arụmọrụ nke HPMC

Nkà na ụzụ dị elu ọ bụghị nanị na-emetụta usoro anụ ahụ nke HPMC, kamakwa ọ na-enwe mmetụta dị ukwuu na njirimara kemịkal ya na mmetụta ngwa.

Ndozi viscosity

Usoro okpomọkụ dị elu nwere ike ịchịkwa nkesa arọ molekụla nke HPMC nke ọma, si otú a na-edozi viscosity ya. Okpomọkụ dị elu na-enyere aka belata ohere nke ịgbaji yinye molekụla, na-eme ka viscosity nke HPMC na ngwọta mmiri kwụsie ike.

Enwetara okpomọkụ na-eguzogide

A na-eme ka nkwụsi ike okpomọkụ nke HPMC dịkwuo mma site na ọgwụgwọ okpomọkụ dị elu. N'ịrụ ngwa agha na nrapado taịlị, HPMC ka nwere ike idowe ezigbo nrapado na ihe mgbochi n'okpuru ọnọdụ okpomọkụ dị elu.

Solubility emelitere

N'oge usoro ikpo ọkụ dị elu, a na-eme ka microstructure nke HPMC dịkwuo mma, na-eme ka ọ dịkwuo nro na mmiri oyi. Karịsịa na gburugburu ebe a na-ewu ụlọ na-ekpo ọkụ, HPMC nwere ike igbari ngwa ngwa wee mepụta ngwọta colloidal otu.

3. Ngwa kpọmkwem nke teknụzụ okpomọkụ dị elu na usoro mmepụta HPMC

Ogbo mmeghachi omume etherification

Site na ime mmeghachi omume etherification na okpomọkụ dị elu nke 80-100 ° C, enwere ike ịbawanye mmeghachi omume nke hydroxypropyl na otu methyl, nke mere na HPMC nwere ọkwa dị elu nke nnọchi na nkwụsi ike ka mma.

ihicha na-etipịa ogbo

Teknụzụ na-ekpo ọkụ na-ekpo ọkụ n'elu 120 Celsius C nwere ike ọ bụghị nanị wepụ mmiri mmiri, kamakwa igbochi HPMC ntụ ntụ na-eme ka ọ ghara ịdị njọ n'oge usoro ihicha. Mgbe nke ahụ gasịrị, a na-eji teknụzụ na-akụpịa okpomọkụ dị elu iji mee ka ụmụ irighiri uzuzu HPMC dịkwuo nro ma dị mma, na-eme ka mgbasa nke ngwaahịa ahụ dịkwuo mma.

Ọgwụgwọ ọgwụgwọ dị elu

Mgbe a na-eji HPMC eme ihe na ihe owuwu ụlọ ma ọ bụ mkpuchi, ọgwụgwọ ọgwụgwọ okpomọkụ dị elu nwere ike imeziwanye nguzogide mgbawa ya, nguzogide sag na njigide mmiri, na-eme ka mmetụta dị mma na-ewu ụlọ na gburugburu ebe siri ike.

4. Uru nke teknụzụ okpomọkụ dị elu na mpaghara ngwa ngwa HPMC

Ihe owuwu ụlọ

N'okpuru ọnọdụ okpomọkụ dị elu, HPMC na-egosi nkwụsi ike dị mma na njigide mmiri na ngwa agha na ntụ ntụ, na-egbochi ngwa ngwa site na akpịrị ịkpọ nkụ na mgbawa.

Ụlọ ọrụ agba

HPMC synthesized site na elu okpomọkụ nwere ezigbo ọkwa na mgbochi sagging mmetụta na latex agba, nke na-eme ka adhesion na-eyi nguzogide nke mkpuchi.

Ụlọ ọrụ ọgwụ

Nkà na ụzụ okpomọkụ dị elu nwere ike imezi otu nke HPMC na mkpuchi ọgwụ ma hụ na nkwụsi ike nke mmetụta ntọhapụ ọgwụ kwadoro.

Ngwa nke teknụzụ okpomọkụ dị elu nkehydroxypropyl methylcelluloseọ bụghị naanị na-eme ka mmepụta mmepụta ihe dị mma, kamakwa na-eme ka arụmọrụ ngwaahịa dịkwuo mma. Site na usoro okpomọkụ dị elu, viscosity, solubility na thermal nkwụsi ike nke HPMC emeela ka ọ dịkwuo mma, na-eme ka ọ nwee atụmanya ngwa ngwa n'ọhịa nke ihe owuwu, mkpuchi na ọgwụ. N'ọdịnihu, na-aga n'ihu ọhụrụ ọhụrụ nke elu okpomọkụ technology, arụmọrụ nke HPMC ga-n'ihu mma, na-eme ka ukwuu onyinye na mmepe nke green na gburugburu ebe obibi enyi na enyi ihe.