Kemịkaghachi kemịkalụ na gbaa ụka nke hydroxypylthylthyl

Hydroxypylththththththylcelllose (hpmc)A na-ejikarị polmer na-agbanye mmiri na mpaghara mmepụta ihe na ahụike, ma nwee ọtụtụ ụkpụrụ ngwa, dị ka ngbanwe a na-achịkwa, nhazi nri na ụlọ. Na kemịkalụ kemịkalụ na usoro ọgwụgwọ ya na-eme ka ọ bụrụ ihe kpatara mmebi na mgbanwe nke cellose na ihe omume metabolics. Iji ghọta mmeghachi omume kemịkalụ nke HPMC na usoro gbaa ụka, anyị ga-ebu ụzọ ghọta ihe nhazi ya na usoro nrụrụ nke cellulose.

1. Ihe nhazi na akụrụngwa nke hydropyythylthyllllose

HPMC bụ ihe na - agbanwe agbanwe site na ntụgharị kemịkal nke sellose (cellulose). Akwa azụ nke yinye moleclar bụ glucose molecules (c6h12o6) site na blycosidic nke agbụ. Otu cellulose n'onwe ya siri ike igbari na mmiri, ma site na iwebata Methyl (-Ch3yypyl (-C3h7opyl) otu, enwere ike ịbawanye mmiri nke ukwuu iji zụlite polible solible. Usoro mgbasa ozi nke HPMC n'ozuzu ha na-agụnye mmeghachi omume nke celloride (ch3cl chloride (Ch3C) n'okpuru ọnọdụ alkaline, na ngwaahịa na-esite na ya enwetara ike hydrophilicity na ndọpụ uche.

2. Mmeghachi omume kemịkal n'oge gbaa ụka

Usoro gbaa ụka nke HPMC na-adabere na mmemme nke microorganisms, nke na-eji HPMC dị ka ihe isi nri carbon na isi nri. Usoro gbaa ụka nke HPMC gụnyere isi ihe ndị a:

2.1. Mmebi nke HPMC

A na-eji cellulose n'onwe ya bụ nke ejikọtara, na hpmc ga-emebi site na microorganisms n'oge a na-ahụ maka ịgba akwụkwọ, na-ebu ụzọ mee ka glucose, xylose, wdg). Usoro a na-agụnyekarị usoro nke ọtụtụ enzymes colullose na-emebi emebi. Mmeghachi omume dị nkọ gụnyere:

A ga-eji hydrolidic hydrolice: The β glycosididic na celdrose modes (dika cellulase), na-eme ka oligchacchare shuga (dika Oligosacrides, wdg). A ga-eji obere microorganisms na-eri ma jiri ya.

Hydrolysis na mwepu nke HPMC: methyl na hydroxypyl na hpmc molekule a ga-ewepụ akụkụ hxrlysis. Aghọtabeghị usoro mmeghachi omume nke ọma, mana enwere ike ịkọwa na gburugburu ebe obibi na-ahụ maka enydysis na-ahụ maka Enchyonliss zoro ezo (dịka Esteroxy Esterase). Usoro a na - eduga na nbibi nke eriri Hpmc na mwepụ nke otu arụ ọrụ, n'ikpeazụ na - akpụ obere shuga dị obere.

2.2. Mmeghachi omume Microbil metabolic

Ozugbo HPMC na-emebi emebi na ụmụ irighiri shuga, microorganisms na-enwe ike ịtụgharị shuga ndị a ka ọ bụrụ ume site na mmeghachi omume enzymatic. Kpamkpam, microorganisms debere gromese n'ime ethanol, lactic acid ma ọ bụ metabolites ndị ọzọ site n'okporo ụzọ gbaa ụka. Microorganisms dị iche iche nwere ike metabolize ngwaahịa HPMC nke ngwaahịa site na ụzọ dị iche iche. Okporo ụzọ metabolic gụnyere:

Glycysis na-abanye na Pyruvate site na enzymes wee gbanwee ike (ATP) na Mitabolites (dịka lactic acid, ethanol, wdg).

Ọgbọ a na-eme ngwa ngwa: N'okpuru ọnọdụ ma ọ bụ hypoxic ọnọdụ, microorganisms na-agbanwe glucose ma ọ bụ ihe arụ, lactic acid, wdg.

2.3. Mmeghachi omume Redox

N'oge usoro ọgwụgwọ nke HPMC, ụfọdụ microorganisms nwere ike ịmalitegharị ngwaahịa dị iche iche site na mmeghachi omume. Iji maa atụ, usoro imepụta nke Ethanol na-esonye na Redox Recations, a na-emepụta glucose iji mepụta pyruvate, wee gbanwee Pyruvate na Ethanol site na mmeghachi omume. Mmeghachi omume ndị a dị mkpa maka ijigide nguzozi nke mkpụrụ ndụ.

3. Njirimara na usoro egwuregwu

N'oge usoro ọgwụgwọ nke HPMC, ihe ndị metụtara gburugburu nwere mmetụta dị mkpa na mmeghachi omume kemịkal. Dịka ọmụmaatụ, pH, okpomọkụ, ihe ndị oxygen na-etisasị, wdg ga-emetụtakwa Metabolism ọnụ ọgụgụ nke microorganisms na ụdị ngwaahịa. Karịsịa okpomoku na pH, ọrụ microbial enzymes nwere ike ịdị iche iche n'okpuru ọnọdụ okpomọkụ na ọnọdụ nke HPMC na ọganihu nke metabolics nke microorganisms microorganisms.

Usoro gbaa ụka nkeHpmcna-enye mmeghachi omume dị mgbagwoju anya, gụnyere hydrolysis nke cellulose, njehie nke hpmc, metabolism nke shuga, na ọgbọ nke ngwaahịa gbaa ụka. Ghọta mmeghachi omume ndị a ọ bụghị naanị na-enye aka bulie usoro ịgba ụka nke HPMC, kamakwa na-enye nkwado usoro maka imepụta mmepụta ọrụ. Site na omimi nke nyocha, enwere ike imelite usoro nke afọ ojuju nke ọma na nke akụ na ụba nke hpmc na mkpụrụ nke hpmc na gburugburu gburugburu ebe obibi, nchedo gburugburu ebe obibi na ubi ndị ọzọ.