N'ala ọgwụ, com sodiumylcellose (cmc) na hydroxyl methylcellose (hpmc) bụ ọgwụ ọnụọgụ abụọ na-eji ọgwụ na arụmọrụ dị iche iche na ọrụ dị iche iche.
Ihe Okike na Njirimara
CMC is a water-soluble cellulose derivative obtained by converting part of the hydroxyl groups of cellulose into carboxymethyl groups. Mmiri solulite na vissiosity nke cmc dabere na ogo ya na ibu ya na oke molecular dị ka ezigbo thitener na nkwụsị.
A na - enweta HPMC site na dochie akụkụ nke otu hydroxy nke cellulose na methyl na ìgwè dị iche iche. E jiri ya tụnyere cmc, HPMC nwere akụkụ siri ike, enwere ike ịgbaze na mmiri oyi na mmiri ọkụ, ma gosipụta viscosisse viscosisse na ụkpụrụ plọg. A na-ejikarị HPMC na-ejikarị ihe nkiri gara aga, ihe nrapado, ndị dị ala ma na-achịkwa ihe ndị nnọchi anya na ọgwụ.
Ubi
Mbadamba
Ke mmepụta mbadamba, a na-ejikarị cmc mee ihe dị ka ihe na-enweghị nsogbu na nrapado. Dị ka ihe na-enweghị nsogbu, cmc nwere ike ịmịcha mmiri ma zaa, na-emekwa ka ịkatọ mbadamba ụrọ na ịba ụba nke ọgwụ. Dị ka ihe mgbochi, cmc nwere ike ịkwalite ike nke mbadamba ụrọ.
A na-eji HPMC kachasị dị ka ihe nkiri gara aga ma na-achịkwa gị na mbadamba na mbadamba. Ihe nkiri ahụ guzobere ike arụ ọrụ ma na-eyi nguzogide, nke nwere ike ichekwa ọgwụ na gburugburu ebe obibi. N'otu oge ahụ, enwere ike iji ihe nkiri na-akpụ akpụ HPMC iji chịkwaa ọnụego ọgwụ. Site na idozi ụdị na usoro nke HPMC, ntọhapụ kwadebe ma ọ bụ mmetụta nzọpụta na-achịkwa.
Capsules
Na nkwadebe Capsule, a na-ejikarị ya eme ihe, ebe a na-eji HPMC mee ihe n'ọtụtụ ebe, ọkachasị na mmepụta nke consules nri. A na-ejikarị sọlfọ ọdịnala eme ihe, mana n'ihi nsogbu nke isi mmalite nke anụmanụ, HPMC abụrụla ihe ndị ọzọ dị mma. Capsule Shell mere nke Hpmc bụghị naanị nwere ezigbo bayoloji, kamakwa ọ na-egbo mkpa nke ndị na-eri nri.
Nri mmiri
N'ihi nsị ya dị oke mma na nke nkwụchi ike, cmc na-ejikarị nkwadebe dị ka usoro ntụziaka, anya na-akwadebe na usoro nkwado. CMC nwere ike ịbawanye viscosity nke mmiri mmiri, si otú a na-eme ka nkwụghachi na nkwụsi ike nke ọgwụ na igbochi ọgwụ mgbochi ọgwụ.
Ngwa nke HPMC na nkwadebe mmiri na-eme ka ihe dị na thicker ndị na-emunssiffers. HPMC nwere ike ịnagide ike na ọtụtụ ụdị ọgwụ ma nwee ike dakọtara n'ụdị ọgwụ dị iche iche na-enweghị mmetụta na arụmọrụ nke ọgwụ. Na mgbakwunye, a na-ejikwa ihe nkiri nke HPMC nke HPMC, dị ka mmetụta ihe nkiri na-eme ihe nkiri na anya.
A na-achịkwa njikere mwepụ
Na-achịkwa nzụchị, ntinye nke HPMC dị oke ama ama. HPMC nwere ike itolite network, a ga-achịkwa ọnụego ọgwụ ahụ site na idozigharị ịta na usoro nke HPMC. A na-ejikarị ala a n'ọtụtụ mbadamba na ntupu. N'ụzọ dị iche, a na-ejikarị CMC na-achịkwa nchịkwa nchịkọta, tumadi n'ihi na ihe owuwu ya n'ụdị adịghị akwụ ụgwọ dịka HPMC.
Nkwụsi ike na ndakọrịta
CMC dara ada nkwụsi ike na ụdị POT dị iche iche ma na-emetụta gburugburu isi acid. Na mgbakwunye, cmc enweghị nkwenkwe na-adịghị mma na ụfọdụ ọgwụ ọgwụ, nke nwere ike ibute ọdịda ọgwụ ma ọ bụ ọdịda.
HPMC na-egosi nkwụsi ike karịa otu pọm-isi, ma nwee ndakọrịta ngwa ngwa. HPMC nwere ike dakọtara na ọtụtụ ihe eji eme ọgwụ na-enweghị emetụta nkwụsi ike na ịdị njikere nke ọgwụ.
Nchedo na Usoro
Ma CPM na HPMC na hpmc na-ahụta ọgwụ na-akpata ọgwụ ma bụrụ ndị akwadoro maka iji ya na ọgwụ nkwadebe ọgwụ site na ụlọ ọrụ nchịkwa na mba dị iche iche. Agbanyeghị, n'oge eji cmc nwere ike ibute ụfọdụ mmeghachi omume nfụka ma ọ bụ eriri afọ ga - emerụ ahụ, ebe Hpmc adịkarịghị akpata mmeghachi omume.
CMC na HPMC nwere uru nke ha na ngwa ọgwụ. Cmc ji ọnọdụ dị mkpa na nkwadebe mmiri n'ihi nnukwu ihe na nkwụsị ya, ebe a na-akwadebe HPMC nke ọma n'ihi ihe nkiri na-achịkwa ya. Nhọrọ nke ọgwụ ga-adabere na Njirimara ọgwụ na-emepụta na nkwadebe asịrị, na-atụle uru na ọghọm nke ha abụọ, ma na-ahọpụta ihe kachasị dabara adaba.
Oge Post: Jul-19-2024