Hydroxypropyl Methylcellulose (HPMC)naMethylcellulose (MC)bụ ụdị mkpụrụ ndụ cellulose abụọ a na-ahụkarị, nke nwere ụfọdụ ọdịiche dị ịrịba ama na nhazi kemịkalụ, ihe onwunwe na ngwa. Ọ bụ ezie na ihe owuwu molekụla ha yiri, a na-enweta ha abụọ site na mgbanwe kemịkalụ dị iche iche na cellulose dị ka ọkpụkpụ bụ isi, mana njirimara na ojiji ha dị iche.
1. Ọdịiche dị na nhazi kemịkalụ
Methylcellulose (MC): Methylcellulose na-enweta site na iwebata otu methyl (-CH₃) n'ime mkpụrụ ndụ cellulose. Nhazi ya bụ iwebata otu methyl n'ime otu hydroxyl (-OH) nke mkpụrụ ndụ cellulose, na-edochikarị otu ma ọ bụ karịa otu hydroxyl. Ihe owuwu a na-eme ka MC nwee ụfọdụ mmiri solubility na viscosity, mana ngosipụta nke solubility na akụrụngwa na-emetụta ogo nke methylation.
Hydroxypropyl Methylcellulose (HPMC): HPMC bụ ngwaahịa methylcellulose (MC) gbanwere ọzọ. Na ndabere nke MC, HPMC na-ewebata otu hydroxypropyl (-CH₂CH(OH)CH₃). Iwebata hydroxypropyl na-eme ka ọ dịkwuo mma na mmiri ma na-eme ka nkwụsi ike ya dị ọkụ, nghọta na ihe ndị ọzọ anụ ahụ. HPMC nwere ma methyl (-CH₃) na hydroxypropyl (-CH₂CH (OH) CH₃) otu n'ime usoro kemịkal ya, ya mere ọ na-agbaze mmiri karịa MC dị ọcha ma nwee nkwụsi ike dị elu.
2. Solubility na hydration
Solubility nke MC: Methylcellulose nwere ụfọdụ solubility na mmiri, na solubility dabere na ogo methylation. N'ozuzu, methylcellulose nwere obere solubility, karịsịa na mmiri oyi, ọ na-adịkarị mkpa iji kpoo mmiri ahụ iji kwalite mgbasa ya. MC agbazere nwere viscosity dị elu, nke bụkwa akụkụ dị mkpa n'ọtụtụ ngwa ụlọ ọrụ.
Solubility nke HPMC: N'ụzọ dị iche, HPMC nwere mmiri solubility ka mma n'ihi iwebata hydroxypropyl. Ọ nwere ike gbaze ngwa ngwa na mmiri oyi, na ọnụego mgbasa ya na-adị ngwa karịa MC. N'ihi mmetụta nke hydroxypropyl, solubility nke HPMC bụghị nanị mma na mmiri oyi, kamakwa ya kwụsie ike na nghọta mgbe mgbasa na-mma. Ya mere, HPMC dabara adaba maka ngwa ndị chọrọ mgbasa ngwa ngwa.
3. Nkwụsi ike okpomọkụ
Nkwụsi ike nke okpomọkụ nke MC: Methylcellulose nwere nkwụsi ike ọkụ na-adịghị mma. Solubility ya na viscosity ga-agbanwe nke ukwuu na okpomọkụ dị elu. Mgbe okpomọkụ dị elu, arụmọrụ nke MC na-emetụta ngwa ngwa site na ire ere ọkụ, ya mere ngwa ya na ọnọdụ okpomọkụ dị elu na-adabere na ụfọdụ mgbochi.
Nkwụsi ike okpomọkụ nke HPMC: N'ihi iwebata hydroxypropyl, HPMC nwere nkwụsi ike thermal ka mma karịa MC. Arụmọrụ HPMC kwụsiri ike na okpomọkụ dị elu, yabụ na ọ nwere ike idowe nsonaazụ dị mma na oke okpomọkụ. Nkwụsi ike okpomọkụ ya na-enyere ya aka iji ya mee ihe n'ọtụtụ ebe n'okpuru ụfọdụ ọnọdụ okpomọkụ dị elu (dịka nri na nhazi ọgwụ).
4. Njirimara viscosity
Viscosity nke MC: Methyl cellulose nwere elu viscosity na aqueous ngwọta na-ejikarị na ọnọdụ ebe elu viscosity chọrọ, dị ka thickeners, emulsifiers, wdg Ya viscosity bụ chiri anya metụtara ịta, okpomọkụ na ogo methylation. Ogo dị elu nke methylation ga-eme ka viscosity nke ngwọta dịkwuo elu.
Viscosity nke HPMC: The viscosity nke HPMC na-adịkarị ntakịrị ala karịa nke MC, ma n'ihi elu mmiri solubility na mma thermal kwụsie ike, HPMC dị mma karịa MC n'ọtụtụ ọnọdụ ebe mma viscosity akara chọrọ. The viscosity nke HPMC na-emetụta molekụla arọ, ngwọta itinye uche na mgbasa okpomọkụ.
5. Ọdịiche dị na mpaghara ngwa
Ngwa nke MC: Methyl cellulose na-ejikarị arụ ọrụ, mkpuchi, nhazi nri, ọgwụ, ihe ịchọ mma na ubi ndị ọzọ. Karịsịa n'ọhịa a na-ewu ihe, ọ bụ ihe mgbakwunye ihe eji arụ ụlọ a na-ejikarị eme ihe maka ịgbatị, na-eme ka adhesion dịkwuo mma na ịrụ ọrụ ihe owuwu. N'ime ụlọ ọrụ nri, enwere ike iji MC mee ihe dị ka onye na-eku ume, emulsifier na stabilizer, a na-ahụkarị ya na ngwaahịa ndị dị ka jelii na ice cream.
Ngwa nke HPMC: A na-eji HPMC eme ihe na ọgwụ, nri, ihe owuwu, ihe ịchọ mma na ụlọ ọrụ ndị ọzọ n'ihi oke solubility ya na nkwụsi ike ọkụ. Na ụlọ ọrụ ọgwụ, HPMC na-ejikarị dị ka ihe excipient maka ọgwụ ọjọọ eme ihe, karịsịa na ọnụ nkwadebe, dị ka a film mbụ, thickener, nkwado-ahapụ gị n'ụlọnga, wdg N'ime nri ụlọ ọrụ, HPMC na-eji dị ka a thickener na emulsifier maka ala-kalori nri, na ọtụtụ-eji salad dressings, oyi kpọnwụrụ nri na ndị ọzọ na ngwaahịa.
6. Ntụle nke ihe ndị ọzọ
Nghọta: Ihe ngwọta HPMC na-enwekarị nghọta dị elu, yabụ na ha dabara adaba maka ngwa ndị na-achọ ọdịdị anya ma ọ bụ translucent. MC ngwọta na-abụkarị turbid.
Biodegradability na nchekwa: Ha abụọ nwere ezigbo biodegradability, enwere ike mebie ya site na gburugburu ebe obibi n'ọnọdụ ụfọdụ, a na-ewerekwa ya dị mma n'ọtụtụ ngwa.
HPMCnaMCbụ ihe abụọ a na-enweta site na mgbanwe cellulose ma nwee ụdị ntọala ndị yiri ya, ma ha nwere nnukwu ọdịiche dị na solubility, nkwụsi ike okpomọkụ, viscosity, nghọta, na mpaghara ngwa. HPMC nwere ka mma mmiri solubility, thermal nkwụsi ike, na nghọta, ya mere ọ ka mma maka oge ndị chọrọ mgbasa ngwa ngwa, nkwụsi ike okpomọkụ, na ọdịdị. A na-eji MC eme ihe n'ọtụtụ oge na-achọ viscosity dị elu na nkwụsi ike dị elu n'ihi viscosity ya dị elu na mmetụta dị mma.
Oge nzipu: Eprel-06-2025