Hydroxypropyl methylcellulose (HPMC) bụ ọkara sịntetik, inert, polymer na-adịghị egbu egbu nke a na-ejikarị eme ihe na ụlọ ọrụ dịka ọgwụ, nri, ihe ịchọ mma na ihe ụlọ. Mmekọrịta dị n'etiti ịdị arọ ya na viscosity nwere mmetụta dị ukwuu na arụmọrụ ya na ngwa dị iche iche.
1. Solubility na ihe nkiri na-emepụta ihe
The viscosity nke HPMC ozugbo na-emetụta ya solubility na mmiri. HPMC nwere viscosity dị ala nwere ike igbari n'ime mmiri ngwa ngwa wee mepụta ngwọta doro anya na nke edo, nke dabara maka ngwa ndị chọrọ mgbasa ngwa ngwa, dị ka ihe ọ drinkụ drinkụ ozugbo ma ọ bụ ọgwụ ozugbo. HPMC na elu viscosity na-achọ ogologo mgbasa oge, ma nwere ike inye mma ọkpụrụkpụ na ike mgbe akpụ a film, otú ọ dabara maka mbadamba mkpuchi, ihe nkiri na-echebe na dị ka a matriks ihe na-akwado-wepụta preparations.
2. Nkwụsi ike na adhesion
HPMC nwere viscosity dị elu na-enwekarị nkwụsi ike na nrapado. Dị ka ihe atụ, mgbe a na-eji dị ka a thickener maka ciment ma ọ bụ gypsum dabeere ngwaahịa na ụlọ ihe, elu viscosity HPMC nwere ike budata mma ya mmiri njide na sag iguzogide, na-enyere aka ịgbatị ewu oge na ibelata cracking. Na ụlọ ọrụ na-emepụta ọgwụ, a na-eji HPMC nwere viscosity dị elu iji chịkwaa ọnụego mwepụta ọgwụ. Nnukwu nchikota ya na-enye ohere ka a na-ahapụ ọgwụ ahụ nwayọọ nwayọọ n'ime ahụ ma mee ka bioavailability nke ọgwụ ahụ dịkwuo mma.
3. Nkwusioru na emulsification
Mgbanwe na viscosity na-emetụtakwa nkwusioru na emulsification Njirimara nke HPMC. N'ihi yinye molekụla dị mkpụmkpụ ya, HPMC nwere viscosity dị ala dabara adaba maka ojiji dị ka onye na-akwụsịtụ. Ọ nwere ike kwụsịtụ ihe ndị na-adịghị sosoluble n'ime ọgwụ mmiri mmiri ma gbochie oke mmiri ozuzo. HPMC na elu viscosity nwere ike na-etolite a ike netwọk Ọdịdị na ngwọta ruru ya ogologo molekul yinye, otú ọ rụrụ mma na nkwụsi ike nke emulsions na suspensions na ike ịnọgide na-enwe uniformity ruo ogologo oge.
4. Rheology na ngwa ngwa
Njirimara rheological nke HPMC bụkwa akụkụ dị mkpa nke viscosity na-emetụta. Ngwọta HPMC na-enweghị viscosity dị ala na-egosipụta mmụba ka mma, dị mfe ịgba na itinye, a na-ejikarị ya na ngwaahịa nlekọta anụ ahụ na agba. Ihe ngwọta HPMC nwere viscosity dị elu na-akpa àgwà dị ka mmiri na-abụghị Newtonian ma nwee njiri mara mma. Nke a na njirimara na-eme ka elu viscosity HPMC mfe aka n'okpuru elu shiee ọnọdụ, mgbe ịnọgide na-enwe a elu viscosity n'okpuru static ọnọdụ, si otú na-emeziwanye ihe nkiri-akpụ na nkwụsi ike nke ngwaahịa.
5. Ihe atụ ngwa
Ebe a na-ere ọgwụ: A na-ejikarị HPMC viscosity dị ala (dị ka 50 cps) maka mkpuchi mbadamba mbadamba ozugbo iji hụ na mwepụta ọgwụ ngwa ngwa, ebe a na-eji HPMC viscosity dị elu (dị ka 4000 cps) maka mbadamba ihe na-adịgide adịgide iji dozie ya. ọnụego ntọhapụ ọgwụ.
Ebe nri: N'ime ihe ọṅụṅụ ozugbo, HPMC nwere obere viscosity nwere ike ịgbaze ngwa ngwa na-enweghị clumping; na bred ngwaahịa, elu-viscosity HPMC nwere ike melite mmiri na-ejide ikike nke mgwakota agwa na welie uto na moisturizing Njirimara nke butere ngwaahịa.
Ogige ihe owuwu: Na ntinye na mkpuchi, obere viscosity HPMC na-eme ka owuwu rụọ ọrụ ma na-eme ka arụmọrụ ọrụ dịkwuo mma; mgbe elu viscosity HPMC enhances na ọkpụrụkpụ na sag iguzogide nke mkpuchi.
Viscosity nke HPMC bụ isi ihe na-ekpebi arụmọrụ ya na ngwa. Low viscosity HPMC na-a na-eji ebe ngwa ngwa mgbasa na flowability na-chọrọ, mgbe elu viscosity HPMC bụ ọzọ uru na ngwa chọrọ elu adhesion, ezi film guzobe na kwụsie ike. Ya mere, ịhọrọ HPMC na ezi viscosity dị oke mkpa iji bulie arụmọrụ ya n'akụkụ dị iche iche.
Oge nzipu: Jul-08-2024