HPMC (Hydroxyl Methylcellose) bụ ihe eji eme mmiri na-agbanye mmiri n'ọtụtụ ebe n'ọhịa, ọgwụ na kemịkalụ nke ụbọchị. O nwere ezigbo ucha, emulsification, fim, colloid na akụrụngwa ndị ọzọ. Na sistemu emulsion, hpmc nwere ike ijikwa viscosity nke emulsion n'ọtụtụ ụzọ.
1. Molecular owu nke HPMC
Ọdịmma nke HPMC na-emetụta oke molecular na ogo nke ihe nnọchi. Nnukwu molecular ibu, onye dị elu na viscosity nke ihe ngwọta ahụ; Na ogo nke dochie anya (nke ahụ bụ, ogo nke dochie anya hydroxyyl na methoxy na methoxy) na-emetụta mkpado na akụrụngwa viscosity Njirimara HPMC. Kpọsị, onye dị elu nke ihe nnọchi, ka mma slublity of hpmc, na viscosity na-abawanye n'otu. Ndị na-emepụta ihe na-enyekarị ngwaahịa HPMC nwere ihe dị iche iche molecular dị iche iche na ogo nke dochie mkpa nke ngwa dị iche iche.
2. Jiri uche
Nta nke HPMC na ihe ngwọta osisi bụ otu n'ime ihe ndị bụ isi na-emetụta viccosity. N'ikwu okwu, elu ịta nke Hpmc, nke viscosity nke ihe ngwọta. Agbanyeghị, viscitity ụdị ụdị HPMC dị iche iche nwere ike iche iche nke ukwuu. Ya mere, na ngwa bara uru, ọ dị mkpa ịhọrọ nkwenye kwesịrị ekwesị nke ngwọta HPMC dị ka usoro viscitis akọwapụtara. Dịka ọmụmaatụ, na ngwa owuwu, a na-achịkwa ịta HPMC n'etiti 0.1% na 1% iji nye ọhụụ ọrụ na-arụ ọrụ na arụmọrụ na-arụ ọrụ na arụmọrụ.
3. Azọ Azọ Azọ Azọ
Usoro ndagide nke HPMC nwekwara mmetụta dị mkpa na viscosity ikpeazụ. HPMC dị mfe ịgbasa mmiri oyi, mana ọnụ ọgụgụ a na-egbughị nwayọ; Ọ na-agbada ngwa ngwa na mmiri ọkụ, mana ọ dị mfe agglomerate. Iji zere agglomeration, enwere ike iji usoro nwayọ nwayọ, ya bụ, buru ụzọ jiri nwayọ tinye HPMC na mmiri oyi iji gbasaa, mgbe ahụ, okpomoku na-akpali ruo mgbe etisasịwo. Na mgbakwunye, HPMC nwekwara ike ịbụ nke a na-ejikwa ya wee tinye mmiri na mmiri iji melite arụmọrụ na nkwụsi ike nghọta.
4. Okpomoku
Okpomọkụ nwere mmetụta dị ukwuu na viscosity nke ngwọta HPMC. Na mkpokọta, viscosity HPMC Nellzọ na-ebelata ka ọnọdụ okpomọkụ na-abawanye. Nke a bụ n'ihi na ebili okpomọkụ ga-emebi njikọta hydrogen n'etiti irighiri ihe, na-eme ka HPMC molecular slide dị mfe, si otú a belata vide ahụ nke ihe ngwọta. Ya mere, n'ime ngwa chọrọ viscosity dị elu, a na-ejikarị azịza HPMC na-abụkarị obere okpomọkụ. Dịka ọmụmaatụ, na ngwa ọgwụ, a na-ejikarị azịza ọgwụ na-eme ihe n'ụlọ okpomọkụ iji hụ na nkwụsi ike na ịdị irè nke ọgwụ.
5. PHO
Olu uru nke HPMC metụtakwara ya. HPMC nwere viscosity kachasị elu n'okpuru ọnọdụ acidic ọnọdụ acidity na nke na-esighi ike, ebe visitsity na-esighi ike ga-agbadata ogo actic ma ọ bụ alkaline siri ike. Nke a bụ n'ihi ụkpụrụ PU PO ga-emebi usoro molecular nke hpmc ma mee ka mmetụta ndị na-esi sie ike. Ya mere, na ngwa bara uru, a ga-achịkwa uru uru nke ihe ngwọta ahụ ma nọgide na-achịkwa ya ma jigide ya n'ime ọnọdụ HPMC (ọ na-abụkarị p 3-11) iji hụ na mmetụta na-akpata ya. Dịka ọmụmaatụ, na ngwa nri, a na-ejikarị HPMC na nri acidic dị ka yogọt na ihe ọ juiceụ juụ, a ga-enwetakwa ọhụụ viscosity site na ịgbanwe uru viscosity site na ịgbanwe uru viscosis site na idozi ọnụ ahịa PH.
6.. Ihe ndị ọzọ
Na sistemu emulsion, a nwekwara ike idozi viscosity HPMC site na ịgbakwunye ndị ọzọ dị egwu ma ọ bụ ihe nkwado. Iji maa atụ, ịgbakwunye nnupụta nke nnu iche (dịka sodium chloride) nwere ike iwelie viscosit nke HPMC Ngwọta; Ka ị na-agbakwunye mgbatị ahụ ndị na-edozi dị ka Ethanol nwere ike belata ya na viscosity. Na mgbakwunye, mgbe ejiri ya na ndị ọzọ na-eme ihe (dị ka chịngọm ndị ọzọ (dịka GUM Xantan, Carbomer, wdg), wdg), viscosity nke emulsion nwekwara ike ịka mma. Ya mere, na imewe usoro n'ezie, a ga-ahọrọ ihe mgbakwunye kwesịrị ekwesị ka achọrọ iji bulie viscosity na arụmọrụ nke emulsion.
HPMC nwere ike nweta njikwa nza nke emulsise site na ihe owuwu ya, iji uche, iji uche, usoro, uru na ihe mgbakwunye. N'ime ihe ndị dị mma, a ga-atụle ihe ndị a mkpa iji họrọ ụdị ụdị HPMC kwesịrị ekwesị iji mezuo mmetụta dị mma. Site na njikwa usoro sayensị, HPMC nwere ike rụọ ọrụ dị mkpa n'ọhịa, ọgwụ, nri na kemịkalụ kwa ụbọchị, na-enye ezigbo ọrụ na ahụmịhe onye ọrụ.
Oge Post: Jul-17-2024