(1) Okwu mmeghe na HPMC
Hydroxypyl Methylcellose (HPMC) bụ nke dị mkpa na-abụghị sel sel sel sel na-ejikarị ihe arụ, ihe eji ewu, nri na ubi ndị ọzọ. Na akwa ịsa ahụ, a na-eji HPMC mee ihe dị ka onye na-asa ahụ iji nye nkwụsi ike na solubality, na-eme ka ndọnye adhesion na ịsacha mmiri ịsa ahụ. Agbanyeghị, iji nweta ọhụụ nke hpmc na akwa ịsa ahụ, ọ dị ọtụtụ mkpa na-atụle, gụnyere ụdị, usoro, usoro, wdg nke HPMC.
(2) Ihe na-emetụta viscosity HPMC
1. Ụdị na ụdị nke HPMC
Ikike molecular na ogo nke dochie (Methoxy na hydroxypyl nbanye) nke HPMC ozugbo metụta Njirimara na Njirimara Viccosity ya. Ofdị hpmc dị iche iche nwere ụdị vices dị iche iche. Họrọ ụdị HPMC nke dabara na akwa akwa gị chọrọ bụ igodo. N'ikwu okwu n'ozuzu, HPMCS dị elu na-enye viscosities dị elu, ebe obere igwe na-ebute obere anya na-enye oghere dị ala.
2. Usoro nke HPMC
Ọnụ ego HPMC nwere mmetụta dị ukwuu na viscosict. A na-etinye HPMC na ọnụọgụ dị n'etiti 0,5% na 2% na-asacha akwa. Usoro onunu ogwu nke di obere agaghị enweta mmetụta a chọrọ, ebe usoro onunu ogwu nke buru oke ibu nwere ike ibute nsogbu dika ihe isi ike na agwakọta. Yabụ, usoro ọgwụgwọ HPMC dị ka mkpa akọwapụtara na nnwale iji nweta vissity kachasị mma.
3. Ngbanwe
Ọnọdụ ọnọdụ HPMC (Oké okpomoku, PHOGER, ọsọ, wdg) nwere mmetụta dị mkpa na vicosity na viscosity ya:
Okpomoku: HPMC suplives jiri nwayọ nwayọ na obere okpomọkụ mana enwere ike inye ndị ọhụụ. Gbasasịwo ngwa ngwa na oke okpomọkụ mana nwere obere viscosity. A na-atụ aro ka igbari hpmc n'etiti 20-40 Celsius C iji hụ na nkwụsi ike na viscosity ya.
PH: HPMC na-arụ ọrụ kachasị mma n'okpuru ọnọdụ anọpụ iche. Valkpụrụ POM POM (oke acidic ma ọ bụ alkaline ma ọ bụ nke nwere ike imebi ihe owuwu HPMC ma belata viscosity ya. Ya mere, na-achịkwa uru nke ihe mgbochi a na-asa akwa dị n'etiti 6-8 na-enyere aka nọgide na-eguzosi ike na viscosis nke HPMC.
Ntuli ọsọ ọsọ: ọsọ na-akpali akpali nwere ike ịkwalite mgbasa nke HPMC, mana oke egwu na-ewetara etemeete ma metụta otu ihe ngwọta. A na-atụ aro ka iji ọsọ na-akpali akpali iji gbazee hpmc.
4. Tinye iwu
HPMC na-adị mfe agglomerates na ngwọta, na-emetụta ya na arụmọrụ na ọhụụ. Ya mere, iwu nke a na-agbakwunye HPMC dị oke mkpa:
Mi-ngwakọta: Gwakọta HPMC na ngwa ndị ọzọ kpọrọ nkụ ọbụna ọbụna na iji nwayọọ nwayọọ tinye ha na mmiri, nke nwere ike igbochi nguzobe clump na enyemaka iji gbochie ya.
Moisturizing: Tupu ịtinye Hpmc na a sara mbara ịsa ahụ, ị nwere ike buru ụzọ mee obere mmiri oyi, wee tinye mmiri ọkụ ka igbari ya. Nke a nwere ike ime ka arụmọrụ na viscosis nke HPMC.
(3) usoro iji bulie viscosity HPMC viscosity
1. Usoro usoro
Họrọ ụdị HPMC kwesịrị ekwesị dabere na iji ọgwụgwụ na ihe achọrọ nke ịsa ahụ. Ibelata nhicha dị elu nwere ike ịchọ viscosity HPMC, ebe ngwaahịa nhicha nwere ike ịhọrọ ọkara karịa viscosity HPMC.
2.. Nnwale nnwale
Na-eduzi ule dị nta na ụlọ nyocha ahụ na-ahụta mmetụta ọ na-emetụta ya na viscosity nke na-asa akwa site na ịgbanwe usoro onunu ogwu, mgbakwunye usoro, wdg nke HPMC. Dekọọ parames na nsonaazụ nke nnwale ọ bụla iji chọpụta njikọta kachasị mma.
3. Mmezi usoro
Tinye usoro Ezi ntụziaka na ọnọdụ usoro iji mepụta akara ma mezie ha maka imepụta nnukwu ihe. Gbaa mbọ hụ na nkesa na nkesa hpmc n'oge usoro mmepụta iji zere nsogbu dịka clumps na mgbasa dara ogbenye.
4. Njikwa Mma
Site na usoro nnwale dị mma, dị ka nha nlele, nyocha nke nha, na-arụ ọrụ nke hpmc na -echeta na ọ ga-enweta viscosity na-atụ anya ma na-arụ ọrụ. Na-eduzi nyocha dị mma ma na-agbanwe usoro na usoro ma ọ bụrụ na achọta nsogbu.
(4) Ajuju ajuju na ngwọta
1. Aghapu nke HPMC
Ihe mere: Ọnọdụ ọkụ na-ekwesịghị ekwesị ma ọ bụ nke na-akpa ike ọsọ ọsọ, mgbakwunye na-adịghị mma, wdg.
Ngwọta: Dozie usoro okpomọkụ ruo 20-40 Celsius C, jiri ọsọ na-akpali akpali ma na-ebulikwa usoro mgbakwunye.
2.
Ihe kpatara: Ihe nlereanya HPMC ekweghị adaba, usoro onunu ogwu ezughi oke, uru pH dị oke elu ma ọ bụ dị ala, wdg.
Ngwọta: Họrọ ụdị HPMC kwesịrị ekwesị, ma na-achịkwa uru a bara uru nke sistemụ ịsa ahụ n'etiti 6-8.
3. HPMC Clump Slump
Ihe kpatara ya: A gbakwụnyere HPMC ozugbo n'ime ngwọta ahụ, ọnọdụ na-adịghị mma, wdg.
Ngwọta: Jiri usoro ejikọta tupu akpa agwakọta, na mbụ gwakọta hpmc na ntụ ọkụ ndị ọzọ, ma jiri nwayọ gbakwunye ya na mmiri igbari.
Iji nweta ọhụụ nke kachasị mma nke hpmc na akwa ịsa ahụ, ihe ndị dị ka ụdị, usoro onunu ogwu, na iji mgbakwunye HPMC tụlere. Site na imewe sayensị, nnwale nnwale na ndozi nhazi, arụmọrụ viscs nke HPMC nwere ike rụọ ọrụ nke ọma, si otú a na-eme ka ọrụ na-adọrọ adọrọ nke akwa akwa.
Oge Post: Jul-08-2024