Hypromellose acid ọ na-eguzogide ọgwụ?

Hypromellose, nke a makwaara dị ka hydroxypropyl methylcellulose (HPMC), anaghị eguzogide acid n'onwe ya. Agbanyeghị, enwere ike ịkwalite nguzogide acid nke hypromellose site na usoro nhazi dị iche iche.

Hypromellose na-agbaze n'ime mmiri mana ọ bụ ihe a na-adịghị ahụkebe na ihe mgbaze organic na mmiri mmiri na-abụghị polar. Ya mere, na gburugburu acidic, dị ka afọ, hypromellose nwere ike ịgbaze ma ọ bụ zaa ruo n'ókè ụfọdụ, dabere na ihe ndị dị ka ntinye nke acid, pH, na oge ikpughe.

Iji meziwanye nguzogide acid nke hypromellose na usoro ọgwụ, a na-ejikarị usoro mkpuchi enteric eme ihe. A na-etinye mkpuchi enteric na mbadamba nkume ma ọ bụ capsules iji chebe ha pụọ ​​​​na gburugburu acidic nke afọ ma kwe ka ha banye n'ime ebe na-anọpụ iche nke obere eriri afọ tupu ha ahapụ ihe ndị na-arụ ọrụ.

A na-ejikarị polymers na-eguzogide ọgwụ gastric acid, dị ka cellulose acetate phthalate (CAP), hydroxypropyl methylcellulose phthalate (HPMCP), ma ọ bụ polyvinyl acetate phthalate (PVAP). Ndị polymer ndị a na-etolite ihe mgbochi na gburugburu mbadamba nkume ma ọ bụ capsule, na-egbochi mgbaze ma ọ bụ mmebi n'ime afọ.

Na nchịkọta, ọ bụ ezie na hypromellose n'onwe ya adịghị eguzogide acid, enwere ike ịkwalite nguzogide acid ya site na usoro nhazi dị ka mkpuchi enteric. A na-ejikarị usoro ndị a eme ihe na usoro ọgwụ iji hụ na nnyefe dị irè nke ihe ndị na-arụ ọrụ na-arụ ọrụ na saịtị ahụ e bu n'obi ime n'ime ahụ.