Nchekwa nke HPMC na mgbakwunye nri

1. Nchịkọta nke HPMC

HPMC (Hydroxypropyl Methylcellulose) bụ ihe mmepụta cellulose nwetara site na mgbanwe kemịkalụ. A na-enweta ya site na cellulose osisi eke site na mmeghachi omume kemịkalụ dị ka methylation na hydroxypropylation. HPMC nwere ezigbo mmiri solubility, viscosity ukpụhọde, film-akpụ Njirimara na nkwụsi ike, ya mere a na-eji ọtụtụ ebe n'ọtụtụ ụlọ ọrụ, karịsịa na ubi nke nri, ọgwụ na ihe ntecha, dị ka a thickener, stabilizer, emulsifier na gelling gị n'ụlọnga.

N'ụlọ ọrụ nri, a na-ejikarị HPMC eme ihe dị ka thickener, gelling agent, huctant, emulsifier na stabilizer. Ngwa ngwa ya na nri gụnyere: achịcha, achịcha, bisikiiti, swiiti, ice cream, condiments, ihe ọṅụṅụ na ụfọdụ nri ahụike. Otu ihe dị mkpa maka ngwa obosara ya bụ na AnxinCel®HPMC nwere ezigbo nkwụsi ike kemịkalụ, ọ dịghị mfe iji ihe ndị ọzọ meghachi omume, ma na-eweda ya ngwa ngwa n'okpuru ọnọdụ kwesịrị ekwesị.

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2. Ntụle nchekwa nke HPMC

Ọtụtụ ụlọ ọrụ na-ahụ maka nchekwa nri nke mba na mba ụwa anabatala ma kwado ya dị ka mgbakwunye nri. A na-enyocha nchekwa ya site n'akụkụ ndị a:

Ọmụmụ toxicology

Dị ka ihe mmepụta nke cellulose, HPMC dabeere na osisi cellulose na nwere dịtụ ala toxicity. Dabere na ọtụtụ ọmụmụ toxicology, iji HPMC na nri anaghị egosi oke nsi na-adịghị ala ala. Ọtụtụ nchọpụta egosila na HPMC nwere ezigbo ihe nrụnye na ọ gaghị ebute mmetụta nsị doro anya na ahụ mmadụ. Dịka ọmụmaatụ, nsonaazụ nke nnukwu nnwale nsi ọnụ ọnụ nke HPMC na ụmụ oke gosiri na ọ nweghị mmeghachi omume nsi doro anya mere na oke doses (karịa ojiji nke mgbakwunye nri kwa ụbọchị).

Nri na ADI (nri kwa ụbọchị anabatara)

Dabere na nyocha nke ndị ọkachamara nchekwa nri, ihe oriri kwa ụbọchị (ADI) nke HPMC agaghị emerụ ahụike mmadụ n'ime oke ojiji. Kọmitii Ọkachamara Mba Nile Maka Mgbakwunye nri (JECFA) na US Food and Drug Administration (FDA) na ụlọ ọrụ ndị ọzọ achọpụtala nchekwa nke HPMC dị ka mgbakwunye nri ma debe oke ojiji maka ya. N'ime akụkọ nyocha ya, JECFA rụtụrụ aka na HPMC egosighi mmetụta nsị doro anya, na ojiji ya na nri na-adịkarị n'okpuru uru ADI setịpụrụ, yabụ ndị na-azụ ahịa ekwesịghị ichegbu onwe ha maka ihe egwu ahụike ọ nwere.

Mmeghachi omume nfụkasị na mmeghachi omume ọjọọ

Dị ka ihe sitere n'okike, HPMC nwere obere mmeghachi omume nfụkasị ahụ. Ọtụtụ ndị mmadụ anaghị enwe mmeghachi ahụ nfụkasị na HPMC. Agbanyeghị, ụfọdụ ndị nwere mmetụta nwere ike ịnwe mgbaàmà nrịanrịa dị nro dị ka ọkụ ọkụ na mkpụmkpụ ume mgbe ha na-eri nri nwere HPMC. Mmeghachi omume ndị dị otú ahụ na-adịkarị ụkọ. Ọ bụrụ na ahụ erughị ala apụta, a na-atụ aro ka ịkwụsị iri nri nwere HPMC ma chọọ ndụmọdụ dọkịta ọkachamara.

Ogologo oge oriri na ahụike eriri afọ

Dị ka ihe dị elu-molecular compound, AnxinCel®HPMC siri ike ịmịnye ahụ mmadụ, mana ọ nwere ike ịrụ ọrụ ụfọdụ dị ka eriri nri na eriri afọ ma kwalite peristalsis intestinal. Ya mere, oriri na-adịghị mma nke HPMC nwere ike inwe mmetụta dị mma na ahụ ike eriri afọ. Dịka ọmụmaatụ, ụfọdụ ọmụmụ egosila na HPMC nwere ikike ụfọdụ n'ịkwalite peristalsis intestinal na ibelata afọ ntachi. Otú ọ dị, ịṅụbiga mmanya ókè nke HPMC nwere ike ịkpata ahụ erughị ala nke eriri afọ, mgbaze afọ, afọ ọsịsa na mgbaàmà ndị ọzọ, ya mere ekwesịrị ịgbaso ụkpụrụ nke imeru ihe n'ókè.

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3. Nkwado ọkwa nke HPMC na mba dị iche iche

China

Na China, a na-edepụta HPMC dị ka ihe mgbakwunye nri ikike, nke a na-ejikarị na candies, condiments, drinks, pasta ngwaahịa, wdg. Dị ka "Standard for the Use of Food Additives" (GB 2760-2014), HPMC kwadoro maka ojiji. na nri dị iche iche ma nwee oke ojiji.

European Union

Na European Union, a na-amatakwa HPMC dị ka ihe mgbakwunye nri dị mma, akpọrọ E464. Dị ka akụkọ nyocha nke European Food Safety Authority (EFSA) si kwuo, HPMC adịghị mma n'okpuru ọnọdụ ojiji akọwapụtara na ọ naghị egosi mmetụta ọjọọ na ahụike mmadụ.

United States

US FDA depụtara HPMC dị ka ihe “Achọpụtara Dị Ka Nchekwa” (GRAS) ma na-enye ohere iji ya na nri. FDA anaghị ewepụta oke usoro onunu ogwu maka ojiji nke HPMC, ma na-enyochakwa nchekwa ya dabere na data sayensị eji eme ya.

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Dị ka ihe mgbakwunye nri,HPMC akwadola n'ọtụtụ mba na mpaghara gburugburu ụwa ma a na-ahụta na ọ dị mma n'ime oke ojiji akọwapụtara. Achọpụtala nchekwa ya site n'ọtụtụ ọmụmụ toxicological na omume ụlọ ọgwụ, ọ dịghịkwa ebute nnukwu mmerụ ahụ na ahụike mmadụ. Agbanyeghị, dị ka ihe mgbakwunye nri niile, oriri nke HPMC kwesịrị ịgbaso ụkpụrụ nke iji ezi uche mee ihe ma zere iribiga ihe ókè. Ndị nwere allergies kwesịrị ịkpachara anya mgbe ha na-eri nri nwere HPMC iji belata ihe omume ọjọọ.

 

HPMC bụ ihe mgbakwunye a na-ejikarị yana nchekwa na ụlọ ọrụ nri, na-etinye obere ihe egwu na ahụike ọha. Site na ọganihu nke sayensị na teknụzụ, nyocha na nlekọta nke AnxinCel®HPMC nwere ike ịkasi ike n'ọdịnihu iji hụ na nchekwa ya.

 


Oge nzipu: Dec-31-2024