Kedu uru dị n'iji hydroxypropyl methylcellulose dị ka capsule oghere?

Ngwaahịa a bụ 2-hydroxypropyl ether methyl cellulose, nke bụ ihe na-emepụta ọkara sịntetik. Enwere ike imepụta ya site na ụzọ abụọ: (1) Mgbe a na-eji soda caustic gwọchaa linters owu ma ọ bụ pulp osisi, a na-agwakọta ha na chloromethane na epoxy Propane reacts, nụchara anụcha na ntụcha iji nweta ya; (2) Jiri ọkwa kwesịrị ekwesị nke methyl cellulose na-agwọ ya na sodium hydroxide, meghachi omume na propylene oxide n'okpuru okpomọkụ dị elu na nrụgide dị elu ruo ọkwa dị mma, ma nụchaa ya. Arọ molekụla dị site na 10,000 ruo 1,500,000.

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★ Dị ọcha eke echiche, welie mgbaze na absorption.

★ Ọdịnaya mmiri dị ala, 5%-8%. Nguzogide mmịpụta siri ike nke mmiri, ihe ndị dị n'ime ya adịghị mfe ime ka ọ dịkwuo njọ, na shei capsule adịghị mfe ime ka ọ gbanwee, ghọọ nke na-egbuke egbuke, na-esikwa ike.

★ Ọ dịghị ihe ize ndụ nke cross-njikọ mmeghachi omume, ọ dịghị mmekọrịta, elu kwụsie ike, ebe ọ bụ na hydroxypropyl methylcellulose bụ cellulose mmepụta, ọ dịghị ihe ize ndụ nke cross-njikọ mmeghachi omume nke protein bekee na gelatin.

★ Nhọrọ dị ala maka ọnọdụ nchekwa:

Ọ fọrọ nke nta ka ọ bụrụ na ọ naghị emebi emebi na mpaghara iru mmiri dị ala, nwere nkwụsi ike dị mma na oke okpomọkụ, capsule adịghịkwa agbawa.

★ Ụkpụrụ Uniform na ezigbo ndakọrịta:

Ọdabara na ụkpụrụ pharmacopoeia nke mba, ọdịdị, nha, ọdịdị na usoro ndochi dị ka gelatin oghere capsules, ọ dịghịkwa mkpa iji dochie ngwá ọrụ na akụkụ.

★ Na-abụghị anụmanụ isi iyi, ọ dịghị nwere ike n'ihe ize ndụ nke ibu hormone ma ọ bụ ọgwụ fọdụrụ n'ime anụ ahụ.

Hydroxypropyl methylcelluloseCapsules efu dị iche na nke omenala gelatin efu capsules. Ha bụ hydroxypropyl methylcellulose (HPMC) nke ejiri osisi pulp mee. Na mgbakwunye na uru nke echiche eke dị ọcha, hydroxypropyl methylcellulose efu capsules nwekwara ike melite absorption na mgbaze nke protein, abụba na carbohydrates, na nwere teknuzu uru na àgwà nke omenala gelatin oghere capsules enweghị. Site na mmụba na-aga n'ihu nke mmata nlekọta onwe onye nke ndị mmadụ, mmepe nke anụ anaghị eri anụ, mkpochapụ ọrịa ehi ara, ọrịa ụkwụ na ọnụ na ahụike mmadụ, yana mmetụta okpukperechi na ihe ndị ọzọ, ngwaahịa capsule dị ọcha sitere n'okike na nke sitere na osisi. ga-abụ ụzọ na-eduga maka mmepe nke ụlọ ọrụ capsule. .


Oge nzipu: Eprel-28-2024