Hydroxypropyl Methylcellulose (HPMC)bụ ihe na-abụghị ionic mmiri-soluble cellulose ewepụtara, nke a na-emepụta kemịkalụ site na cellulose osisi eke. Ihe owuwu ya nwere otu methyl na hydroxypropyl, nke na-eme ka ọ nwee ezigbo mmiri solubility, nkwụsi ike, nkwụsi ike na imepụta ihe nkiri. N'ihi ihe ndị a pụrụ iche, a na-eji HPMC eme ihe n'ọtụtụ ebe dị iche iche, n'ime nke ngwa ya na ncha akwa dịkwa oke mkpa.
1. Thickerers na viscosity regulators
Na ncha, otu n'ime isi ọrụ nke HPMC bụ dị ka thickener. Ọ nwere ike ịbawanye viscosity nke ihe nchacha nke ọma, na-eme ka ahụmịhe ojiji ha na arụmọrụ ha dịkwuo mma. Maka ihe ndị na-edozi mmiri, karịsịa ihe ndị na-etinye uche dị elu, ịgbara mmiri na-enyere aka ịchịkwa mmiri nke ncha ahụ, na-eme ka ọ kwụsie ike n'oge a na-eji ya eme ihe na o yikarịrị ka ọ ga-edozi ma ọ bụ dozie na karama ahụ. Na mgbakwunye, viscosity kwesịrị ekwesị na-enyekwa aka ibelata mkpofu nchacha ma na-eme ka adhesion ya dịkwuo mma, si otú ahụ na-eme ka mmetụta ịsa ahụ dịkwuo mkpa.
2. Mma nkwụsi ike nke surfactants
Ihe nchacha na-enwekarị surfactants, na arụmọrụ nke ndị a surfactants nwere ike imetụta ihe gburugburu ebe obibi (dị ka okpomọkụ, pH, wdg). Dị ka a thickener na stabilizer, HPMC nwere ike imeziwanye arụmọrụ nke detergents n'okpuru ọnọdụ dị iche iche site n'ịgbanwe viscosity nke ngwọta na-eme ka mgbasa na nkwụsi ike nke surfactants. Ọ na-enyere aka belata nkwụsịtụ nke ụfụfụ ma nọgide na-adịgide adịgide nke ụfụfụ mmiri, karịsịa n'oge usoro nhicha ebe ụfụfụ kwesịrị ịdị ogologo oge.
3. Mma mmetụta ihicha
Adhesion nke HPMC na-enye ohere ka ihe ndị na-arụ ọrụ na detergents na-eme ka ọ dịkwuo mma n'elu ma ọ bụ akwa ákwà, na-eme ka mmetụta dị ọcha dịkwuo mma. Karịsịa n'ime ihe nchacha, HPMC na-enyere aka melite nsị nke unyi na mmiri, na-enye ohere ka ewepụ ha nke ọma. Na mgbakwunye, HPMC nwekwara ike melite arụmọrụ ihicha site n'ibelata nrịba nke ncha ka ọ na-anọ na kọntaktị na unyi ruo ogologo oge.
4. Mee ka akpụkpọ ahụ dịkwuo mma nke ncha
Dị ka ihe sitere n'okike, HPMC nwere ezigbo biocompatibility yana ihe dị nro. Ịtinye HPMC na ncha akwa nwere ike ime ka ịdị nwayọọ nke mmetụ akpụkpọ ahụ dịkwuo mma ma belata mgbakasị ahụ akpụkpọ ahụ. Karịsịa maka ncha nwa ma ọ bụ ihe nchacha emebere maka akpụkpọ ahụ dị nro, HPMC nwere ike ịme ụfọdụ mmetụta na-ebelata, na-eme ka ncha ahụ dịkwuo mma maka iji mee ihe n'ọnọdụ ebe ọ na-akpakọrịta akpụkpọ ahụ ruo ogologo oge.
5. Membrane guzobere na nchebe
HPMCnwere ike imepụta ihe nkiri. N'ime ụfọdụ ngwaahịa ncha, HPMC nwere ike ịmepụta ihe nkiri n'oge usoro nhicha iji nyekwuo nchebe. Dịka ọmụmaatụ, na ụfọdụ ncha akwa ma ọ bụ ihe nchacha, ihe nkiri HPMC nwere ike inye aka chebe elu ákwà ahụ site na oke esemokwu ma ọ bụ mmebi, si otú ahụ gbasaa ndụ ọrụ nke ákwà ahụ.
6. Melite mmetụta nke ncha
N'ihi ihe na-eme ka ọ sie ike na emulsifying, HPMC nwere ike imeziwanye mmetụta nke ncha, na-eme ka ha dị nro ma dị mfe itinye. Dịka ọmụmaatụ, n'ime ihe nchacha nke a na-eji ihicha kichin ma ọ bụ ime ụlọ ịwụ ahụ, HPMC na-enye onye na-ehicha ihe ka ọ nọrọ ogologo oge n'elu, na-enye ohere iwepụ unyi zuru oke na-enweghị ịgbapụ ngwa ngwa.
7. Dị ka onye na-akwado ntọhapụ
N'ime ụfọdụ ngwaahịa nchacha pụrụ iche, HPMC nwekwara ike iji dị ka ihe ntọhapụ na-adịgide adịgide. N'ihi na HPMC na-agbaze nwayọọ nwayọọ, ọ nwere ike igbu oge ntọhapụ nke ihe ndị na-arụ ọrụ n'ime ihe nchacha, na-ahụ na ihe ndị na-arụ ọrụ nwere ike ịga n'ihu na-arụ ọrụ n'oge usoro nhicha dị ogologo, si otú a na-eme ka mmetụta ịsa ahụ dịkwuo mma.
8. Nchekwa gburugburu ebe obibi na nkwado
Dị ka ngwakọta polymer sitere na osisi eke, HPMC nwere ụfọdụ uru na nchekwa gburugburu ebe obibi. Tụnyere ụfọdụ kemịkalụ sịntetik sitere na mmanụ ala, HPMC ka mma na-emebi emebi na mmiri na ọ gaghị ebute ibu dị ogologo oge na gburugburu ebe obibi. Site na ọganihu nke akwụkwọ ndụ akwụkwọ ndụ na echiche enyi na gburugburu ebe obibi, ọtụtụ ndị na-emepụta ihe ncha akwa amalitela iji ihe ndị sitere n'okike na ihe ndị na-emebi emebi. HPMC aghọwo ezigbo nhọrọ n'ihi ezi biodegradaability ya.
Ngwa nkehydroxypropyl methylcellulosena nchacha na-egosipụtakarị n'ọtụtụ akụkụ dị ka ịgbatị, nkwụsi ike, meziwanye mmetụta nhicha, ime ka enyi anụ ahụ dịkwuo mma, mmepụta ihe nkiri, ime ka mmetụ aka na ntọhapụ na-adịgide adịgide. Ntugharị ya na-eme ka ọ bụrụ ihe a na-ejikarị eme ihe na ncha ọgbara ọhụrụ, karịsịa ncha mmiri mmiri, ihe nchacha ọcha, ihe nlekọta anụ ahụ na ngwaahịa ndị ọzọ. Dị ka ndị na-azụ ahịa'chọrọ maka gburugburu enyi na enyi na-asachapụ nke ọma, HPMC, dị ka a eke na-adigide ihe mgbakwunye, nwere sara mbara ngwa atụmanya na-eme n'ọdịnihu ncha ụlọ ọrụ.
Oge nzipu: Dec-11-2024