Test modi
Modum Name: Hypromellose-determinatio Hydroxypropoxy Group-determinatio Hydroxypropoxy Group
Scope of Application: Hoc modum utitur hydroxypropoxy determinare modum determinare de hydroxypropoxy in Hypromellose. Hoc modum est applicabilis ad Hypromellose.
Principium modum:Calculate adContent of hydroxypropoxy in test productum secundum hydroxypropoxy determinatio modum.
Reagent:
I. XXX% (G / G) Chromium solution
II. Hydroxide
III. Phenolphthalein indicator solution
IV. Sodium bicarbonate
V. Dilutum sulphuric acidum
VI. Kalium iodide
VII. Sodium thiosulfate titration solutio (0.02Mol / l)
VIII. Tonde Tonde
Equipment:
Sample Praeparatio:
I. Sodium hydroxide titration solutio (0.02Mol / L)
Praeparatio: 5.6ml ex patet sodium sodium hydroxide solution, addere recens aquas frigida aqua ad eam 1000ml.
Calibration: Take de 6G of Latin Kalium hydrogenii Phthalate exaruit CV ° C constans pondus, ponderis accuratius, addere 50ml de recens coctum frigidam aquae, quassum ut dissolvere quantum fieri potest; Addere II guttae de phenililphthalein indicator solutio, utere hoc liquidum titratu, cum appropinquare finem punctum, in potassium hydrogenii phthalate debet esse omnino dissolvi, et titrated usque ad solutionem fit rosea. Omni 1ml de sodium hydroxide titrationis solution (1Mol / l) est equivalent ad 20.42mg de potassium hydrogenii Phthalate. Calculate concentration huius solution fundatur in consummatio huius solution et moles potassium hydrogenii phthalate capta. Quantitative dilute V temporibus facere concentration 0.02Mol / l.
PRAECLUSIO Ponite in Polyethylene plastic utrem et servavit; Sunt II foramina in obturaculum, et I speculum tubo inseritur in se foraminis, I tubus coniungitur cum a nitri calce fistulam et I tubus adhibetur ad lactentem ex liquido.
II. Phenolphthalein indicator solution tolle 1g of Phenilphthalein, adde 100ml de Ethanol ad dissolvere
III. Sodium thiosulfate titration solution (0.02Mol / L) Praeparatio: Take 26G de sodium thiosulfate et 0.20g de anhydrous sodium carbonate, addere in 1000ml, excutite bene, et locus in I mensis filter. Calibration: take about 0.15g of standard potassium dichromate dried at 120°C with constant weight, accurately weigh it, put it in an iodine bottle, add 50mL of water to dissolve, add 2.0g of potassium iodide, shake gently to dissolve, add 40ml de diluto sulphuric acidum excutite et sigillum arte; Post X minuta in tenebris est, addere 250ml aquae ad dilutionem, et cum solutio est titrated ad circa finem punctum, addere 3ml amulum indicator solution, continue titrata, et in color, et continue viride, et peritum adhibetur sicut blank iudicii disciplinam. Omnis 1ml de sodium thiosulfate (0.1Mol / l) est equivalent ad 4.903G de kalium dichromate. Adice concentration solutionis secundum ad consummatio de solutione et moles potassium dichromate capta. Quantitative dilute V temporibus facere concentration 0.02Mol / l. Si locus temperatus est supra XXV ° C, et temperatus ad reactionem solution et dilution aqua debet refrigerari ad circiter XX ° c.
IV. Tonde 0.5G solution Testis Tonde of Satisful amulum, addere 5ml aqua et movent bene, tunc tardius effundam in 100ml ferventis aqua, movent, ut additur, permanere ad II minuta, sit refrigescant, et effundam supernatant; Et factum est.
Solutio ut recens usum.
Operatio Steps: Take 0.1g huius productum, ponderis verius, posuit in Distillation utrem D, addere 10ml de XXX% (g / g) Cadmium trichloride solutio. Replete vapor generating fistulam B cum aqua ad iuncturam et coniungere distillationis unitas. B et b et d in oleum balineum (non potest esse glycerin), ut liquor gradu de oleum balineum consistent cum liquido gradu Cadmium trichloride solutio in utrem D, conversus in refrigerationem aquae et necessitate, Et NITROGENIUM amnis fluxus in et control ejus fluxus rate ad I bulla per secundam. Intra XXX minuta, elevare temperatus et oleum balneum ad 155ºC, et ponere hoc temperatus ad L ml de distillate colligitur, removere condenser fistulam a fractione columna solution, addere III, et incorporate in collectis solution, addere III et incorporate in collectis solution, adde III Guttae de phenililphthalein indicator solution, et titre ad PH valorem est 6.9-7.1 (metiri cum acoreum metri), recordum consumptum volumen V1 (ml 10ml et sulphuric acidum et stabit Donec ultra ipsum dioxide prodit, addere 1.0g de kalium äthy, et signare, excutite bene, in tenebris ad V minuta, addere 1ml amulum indicator solution (0.02Mol / L) ad In finem punctum, recordum de consumptis volumen V2 (ml). In alia blank test, recordum volutpat VA et VB (ml) de consumptis sodium hydroxide titration solution (0.02Mol / l) et sodium thiosulfate (0.02Mol / l) respectively.
Post tempus: Apr-25-2024