Hydroxypropyl methylcellulose (HPMC)he pūhui polymer wairewa-wairewa e whakamahia nuitia ana, e whakamahia nuitia ana i roto i nga rongoa, kai, taonga hanga whare, whakapaipai me etahi atu mara. He pai te wairewa me nga ahuatanga pokey a HPMC ka taea e ia te hanga i tetahi otinga colloidal pumau, na reira ka whai waahi nui ki nga tono maha. Kia taea ai te takaro katoa ki te mahi a te HPMC, he mea nui te tikanga whakakorenga tika.
1. Tikanga weranga wai pāmahana noa
Ka taea te rewa te HPMC ki te wai matao, engari ko te nuinga o te waa me whai pukenga ki te karo i tona whakahiatotanga. Hei whakapai ake i te painga o te whakakore, ka taea te whakamahi i nga waahanga e whai ake nei:
Hipanga 1: Tāpirihia te HPMC ki te wai
I te pāmahana rūma, tuatahi tauhiuhia te HPMC ki runga i te mata wai kia kore e ringihia te nui o te HPMC ki te wai i te wa kotahi. Nā te mea he pūhui waerau te HPMC, ko te taapiri tika i te nui o te HPMC ka kuhu te wai me te pupuhi tere ki roto i te wai ka hanga he matū rite te kiri.
Hipanga 2: Te whakaoho
I muri i te taapiri i te HPMC, me whakaoho tonu. Na te mea he matūriki pai te HPMC, ka pupuhi i muri i te tangohanga o te wai hei hanga i te matū-rite. Ka awhina te whakakorikori ki te aukati i te HPMC ki te whakahiato ki roto ki nga kapoipoi.
Hipanga 3: Tu me te whakaoho ano
Ki te kore e tino rewa te HPMC, ka waiho te otinga kia tu mo tetahi wa ka haere tonu ki te whakaoho. Ko te tikanga ka memeha katoa i roto i etahi haora.
He pai tenei tikanga mo nga waahi kaore e hiahiatia ana te whakamahana, engari he roa te waa ki te whakarite kia tino memeha te HPMC.
2. Tikanga wetewete wai wera
He tere ake te rewa o te HPMC i roto i te wai mahana, na te whakamahana i te pāmahana wai ka taea te whakatere i te mahi whakakore. Ko te 50-70 ℃ te pāmahana wai whakawera e whakamahia nuitia ana, engari he nui rawa te pāmahana (penei i te 80 ℃) ka heke te HPMC, no reira me whakahaere te pāmahana.
Hipanga 1: Whakawera wai
Whakawerahia te wai ki te 50 ℃ me te pupuri tonu.
Hipanga 2: Tāpiri HPMC
Me āta tauhiuhia te HPMC ki te wai wera. Na te nui o te wera o te wai, ka ngawari ake te memeha a HPMC, ka whakaiti i te whakahiatotanga.
Hipanga 3: Te whakaoho
Whai muri i te taapiri i te HPMC, me whakaoho tonu te wairewa wai. Ko te huinga o te whakamahana me te whakaoho ka taea te whakatairanga i te tere tere o te HPMC.
Hipanga 4: Kia mau tonu te pāmahana me te whakaoho tonu
Ka taea e koe te pupuri i tetahi pāmahana me te whakaoho tonu kia rewa katoa te HPMC.
3. Tikanga Whakakore Waipiro
Ka taea te whakakore i te HPMC i roto i te wai anake, engari ano hoki i etahi whakarewa waipiro (penei i te waihano). Ko te painga nui o te tikanga whakakore waipiro ko te whakapai ake i te whakarewatanga me te whakamararatanga o te HPMC, ina koa mo nga punaha he nui te wai.
Hipanga 1: Whiriwhiria he whakarewa waipiro pai
Ka whakamahia nga whakarewa waipiro penei i te waiwaro me te isopropanol ki te whakakore i te HPMC. Ko te tikanga, ko te 70-90% te wairewa waihano he pai ake te painga ki te whakakore i te HPMC.
Hipanga 2: Dissolution
Me ata tauhiuhia te HPMC ki roto i te whakarewa waipiro, me te whakakorikori i te taapiri kia tino marara te HPMC.
Hipanga 3: Tu me te whakaoho
Ko te tukanga o te whakarewa waipiro te whakakore i te HPMC he tere, a he maha nga meneti hei whakatutuki i te whakakorenga.
Ko te tikanga whakakore waipiro ka whakamahia i roto i nga ahuatanga tono e hiahia ana kia tere ake te whakakore me te iti o te wai.
4. Ko te whakarewa-wai te tikanga whakangao whakangao
I etahi wa ka rewa te HPMC ki te ranunga o tetahi wahanga o te wai me te whakarewa. He tino pai tenei tikanga mo nga ahuatanga e tika ana kia whakatikahia te pokey o te otinga, te reeti memeha ranei. Ko nga whakarewa noa ko te acetone, te waihano, aha atu.
Hipanga 1: Whakaritehia te otinga
Kōwhiria he ōwehenga pai o te whakarewa me te wai (hei tauira, 50% wai, 50% wairewa) me te whakamahana ki te pāmahana pai.
Hipanga 2: Tāpiri HPMC
I te wa e whakakorikori ana, me ata taapirihia te HPMC kia rite te whakakorenga.
Hipanga 3: Whakatikatika atu
I te wa e hiahiatia ana, ka taea te whakanui ake i te waahanga o te wai, te whakarewa ranei hei whakatika i te whakarewatanga me te viscosity o HPMC.
He pai tenei tikanga mo nga wa ka taapirihia nga whakarewa pararopi ki nga wairewa wai hei whakapai ake i te reiti memeha, hei whakatika ranei i nga ahuatanga o te otinga.
5. Ultrasonic-awhina whakakore tikanga
Ma te whakamahi i te hua oscillation teitei o te ultrasound, ka taea e te tikanga whakakorenga awhina ultrasonic te whakatere i te tukanga whakakorenga o te HPMC. He tino pai tenei tikanga mo te nui o te HPMC me tere te rewa, a ka taea te whakaiti i te raru whakahiato ka puta i te wa o te whakaoho tuku iho.
Hipanga 1: Whakaritehia te otinga
Tāpirihia te HPMC ki te nui o te wai, te wairewa whakauru wai ranei.
Hipanga 2: Ultrasonic maimoatanga
Whakamahia he kaihoroi ultrasonic, he ultrasonic dissolver ranei ka rongoa kia rite ki te kaha me te wa kua whakaritea. Ko te awe oscillation o te ultrasound ka taea te whakatere i te tukanga whakakorenga o te HPMC.
Hipanga 3: Tirohia te pānga memeha
I muri i te maimoatanga ultrasonic, tirohia mehemea kua tino memeha te otinga. Mena he waahanga kaore i pakaru, ka taea te mahi ano i te maimoatanga ultrasonic.
He pai tenei tikanga mo nga tono e hiahia ana kia pai te whakakore me te tere.
6. Te maimoatanga i mua i te whakakorenga
Hei karoHPMCte whakahiato, te uaua ranei ki te memeha, ka taea te whakamahi etahi tikanga whakamaoritanga, penei i te whakaranu i te HPMC me etahi atu whakarewa (penei i te glycerol), te whakamaroke i te tuatahi, te whakamakuku ranei i te HPMC i mua i te taapiri whakarewa. Ka taea e enei mahi maimoatanga te whakapai ake i te whakarewatanga o te HPMC.
He maha nga huarahi ki te whakakore i te HPMC. Ko te whiriwhiri i tetahi tikanga whakakorenga pai ka taea te whakapai ake i te pai o te whakakore me te kounga o te hua. Ko te tikanga whakamaarama o te rūma e pai ana mo te taiao ngawari, ka taea e te tikanga whakamaarama wai wera te tere ake i te tukanga whakakorenga, me te tikanga whakakore waipiro me te tikanga whakarewa-wai-wai-wai e tika ana mo te whakakore me nga hiahia motuhake. Ko te tikanga whakakorenga awhina ultrasonic he huarahi whai hua hei whakaoti i te tere tere o te nui o te HPMC. E ai ki nga whakaritenga tono motuhake, ko te kowhiringa ngawari o te tikanga whakakorenga e tika ana ka taea te whakarite i nga mahi pai o te HPMC i nga waahi rereke.
Wā tuku: Tihema-19-2024