Onse hydroxypropyl methylcellulose ndi hydroxyethyl cellulose ndi mapadi

Hydroxypropyl methylcellulose (HPMC)ndi hydroxyethyl cellulose (HEC) ndi zinthu ziwiri zofunika zochokera ku cellulose zomwe zimagwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana chifukwa cha mawonekedwe awo apadera. Ngakhale onsewa amachokera ku cellulose, ali ndi mawonekedwe apadera amankhwala ndipo amawonetsa mawonekedwe ndi ntchito zosiyanasiyana.

1. Chiyambi cha Ma cellulose Derivatives:
Cellulose ndi polysaccharide yachilengedwe yomwe imapezeka m'makoma a cell ya zomera, yopangidwa ndi mizere yozungulira ya mayunitsi a shuga olumikizidwa ndi β(1→4) glycosidic bond. Ma cellulose amatengedwa posintha ma cellulose kuti apititse patsogolo zinthu zinazake kapena kuyambitsa magwiridwe antchito atsopano. HPMC ndi HEC ndi zotuluka ziwiri zotere zomwe zimagwiritsidwa ntchito kwambiri m'mafakitale kuyambira zamankhwala mpaka zomangamanga.

2. Kaphatikizidwe:
HPMC imapangidwa pochita ma cellulose ndi propylene oxide kuyambitsa magulu a hydroxypropyl ndipo kenako methyl chloride kuyambitsa magulu a methyl. Izi zimapangitsa kuti magulu a hydroxyl alowe m'malo mwa cellulose, kutulutsa mankhwala okhala ndi mphamvu zosungunuka komanso kupanga mafilimu.

HEC, kumbali ina, imapangidwa ndikuchitapo kanthu kwa cellulose ndi ethylene oxide kuti iphatikize magulu a hydroxyethyl. Mlingo wa substitution (DS) mu HPMC ndi HEC ukhoza kuwongoleredwa posintha momwe zinthu zimachitikira, zomwe zimakhudza mawonekedwe awo monga mamasukidwe akayendedwe, solubility, ndi machitidwe a gelation.

3. Kapangidwe ka Chemical:
HPMC ndi HEC zimasiyana mumitundu yamagulu olowa m'malo omwe amalumikizidwa ndi msana wa cellulose. HPMC ili ndi magulu onse a hydroxypropyl ndi methyl, pomwe HEC ili ndi magulu a hydroxyethyl. Zoloŵa m'malozi zimapereka mikhalidwe yapadera ku chotuluka chilichonse, kusonkhezera machitidwe awo m'magwiritsidwe osiyanasiyana.

4. Katundu Wathupi:
Onse HPMC ndi HEC ndi ma polima osungunuka m'madzi okhala ndi zinthu zabwino kwambiri zokhuthala. Komabe, amawonetsa kusiyana kwa kukhuthala, mphamvu ya hydration, komanso luso lopanga mafilimu. HPMC nthawi zambiri imakhala ndi mamasukidwe apamwamba kwambiri poyerekeza ndi HEC pamlingo wofanana, ndikupangitsa kuti ikhale yoyenera kugwiritsa ntchito zomwe zimafunikira kukhuthala kwambiri.

Kuphatikiza apo, HPMC imapanga mafilimu omveka bwino komanso ogwirizana kwambiri chifukwa cha zolowa m'malo mwa methyl, pomwe HEC imapanga makanema ofewa komanso osinthika kwambiri. Kusiyanasiyana kwamakanema awa kumapangitsa kuti chotuluka chilichonse chikhale choyenera kugwiritsidwa ntchito pazamankhwala, zinthu zosamalira anthu, komanso m'mafakitale azakudya.

5. Mapulogalamu:
5.1 Makampani Opanga Mankhwala:
Onse a HPMC ndi HEC amagwiritsidwa ntchito kwambiri popanga mankhwala monga zomangira, zonenepa, ndi zokutira mafilimu. Amathandizira kukhulupirika kwa piritsi, kuwongolera kutulutsidwa kwa mankhwala, komanso kumapangitsa kuti pakamwa pakamwa pamapangidwe amadzimadzi. HPMC imakondedwa kuti ikhale yotulutsa nthawi zonse chifukwa cha kuchepa kwake kwamadzimadzi, pomwe HEC imagwiritsidwa ntchito kwambiri popanga njira zamaso ndi zopaka pamutu chifukwa cha kumveka kwake komanso kugwirizana ndi madzi achilengedwe.

5.2 Makampani Omanga:
M'makampani omanga,Mtengo wa HPMCndiHECamagwiritsidwa ntchito ngati zowonjezera muzinthu zopangidwa ndi simenti, monga matope, ma grouts, ndi ma renders. Amathandizira kugwirira ntchito, kusunga madzi, ndi kumamatira, zomwe zimapangitsa kuti ntchito yomaliza ikhale yolimba komanso yolimba. HPMC nthawi zambiri imakondedwa chifukwa cha kuchuluka kwake kosungira madzi, komwe kumachepetsa kusweka ndikuwongolera nthawi yokhazikitsa.

5.3 Zosamalira Munthu:
Zotulutsa zonsezo zimapeza ntchito muzinthu zosamalira anthu monga ma shampoos, mafuta odzola, ndi zopaka mafuta monga zokhuthala, ma emulsifiers, ndi zolimbitsa thupi. HEC imapereka mawonekedwe osalala komanso onyezimira pamapangidwe, ndikupangitsa kuti ikhale yoyenera pazosamalira tsitsi ndi zopakapaka pakhungu. HPMC, yokhala ndi mawonekedwe apamwamba kwambiri opangira mafilimu, imagwiritsidwa ntchito popanga zoteteza ku dzuwa ndi zodzikongoletsera zomwe zimafuna kukana madzi komanso kuvala kwanthawi yayitali.

5.4 Makampani a Chakudya:
M'makampani azakudya, HPMC ndi HEC zimagwira ntchito ngati zolimbitsa thupi, zolimbitsa thupi, komanso zopangira ma texturizer pazinthu zosiyanasiyana kuphatikiza ma sosi, mavalidwe, ndi zokometsera. Amathandizira pakamwa pakamwa, amalepheretsa syneresis, komanso amawonjezera mphamvu zamapangidwe azakudya. HPMC nthawi zambiri amakonda kumveka kwake komanso kukhazikika kwa kutentha, ndikupangitsa kuti ikhale yoyenera kugwiritsa ntchito zomwe zimafunikira ma gels owonekera komanso ma emulsions okhazikika.

6. Mapeto:
hydroxypropyl methylcellulose (HPMC) ndi hydroxyethyl cellulose (HEC) ndi zotuluka pa cellulose zomwe zimakhala ndi kapangidwe kake, katundu, ndi ntchito. Ngakhale onsewa amapereka mawonekedwe abwino kwambiri okhuthala komanso kupanga mafilimu, amawonetsa kusiyanasiyana kwa kukhuthala, kumveka bwino kwamakanema, komanso kachitidwe ka hydration. Kumvetsetsa kusiyana kumeneku ndikofunikira posankha chotengera choyenera pakugwiritsa ntchito m'mafakitale onse monga mankhwala, zomangamanga, chisamaliro chaumwini, ndi chakudya. Pamene kafukufuku akupitilirabe, kusinthidwa kwina ndikugwiritsa ntchito zotumphukira za cellulose zikuyembekezeredwa, zomwe zikuthandizira kupitilizabe kufunikira kwawo m'mafakitale osiyanasiyana.