Kusungunula hydroxypropyl (hpmc) m'madzi ndichikhalidwe chodziwika bwino m'mafakitale osiyanasiyana, kuphatikizapo zamafakitale osiyanasiyana, kuphatikiza mankhwala, chakudya, zodzola komanso zomangamanga. HPMC ndi kuchotsa kwa cellulose komwe kumapanga mawonekedwe owoneka bwino, opanda utoto, komanso mawonekedwe a viscous mukasakanikirana ndi madzi. Njira yothetsera mavutowa imawonetsa zinthu zapadera ngati zamphamvu, kumanga, kupanga filimu, komanso kulimbikitsa kwa zosakaniza. Kutha kwa HPMC m'madzi kumaphatikizapo njira zina zowonetsetsa kuti muchepetse kubereka komanso kufanana.
Kuyamba kwa HPMC:
Hydroxypypyl methylcellulose (hpmc) ndi ma cellulose ether etherd kuchokera ku cellulose yachilengedwe. Amapangidwa ndi kuchiritsa cellulose ndi ma propylene oxide ndi methyl chloride. HPMC imagwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana chifukwa cha mawonekedwe ake abwino kwambiri, akukula, okhazikika, komanso madzi osunga madzi. Ntchito yoyamba ya HPMC ikuphatikiza:
Mankhwala ogulitsa: ogwiritsidwa ntchito ngati chofunda, kanema wakale, wosuta wosinthika, komanso omasulidwa - mapiritsi, mafuta, mafuta.
Makampani Ogulitsa Chakudya: Kugwiritsa ntchito ngati thiccener, hitabilite, emulsifier, ndi chinyezi chosunga msuzi monga msuzi, mkaka, komanso zinthu zophika.
Ntchito Yomanga Madzi, zomata, zomata, komanso kukula kwazinthu za mmenga, ma gypsum-poschents, ndi tiles.
Zodzikongoletsera: Ntchito ngati Thicner, kanema wakale, ndi emulsion okhazikika mu mafuta odzola, mafuta, shampoos, ndi zinthu zosamalira payekha.
Kusintha kwa HPMC m'madzi:
Kusungunula HPMC m'madzi kumaphatikizapo njira zingapo zazikulu zokwaniritsira yunifolomu komanso njira yothetsera:
Kusankha kwa HPMC Gawo: Sankhani malo oyenera a hpmc kutengera ma viscle yofunikira, tinthu tating'onoting'ono, komanso mulingo wolowa m'malo. Masukulu osiyanasiyana amapereka madigiri osiyanasiyana a ufa.
Kukonzekera kwamadzi: gwiritsani ntchito madzi oyeretsedwa kapena oyeretsedwa kukonza yankho. Mtundu wamadzi ungakhudze kwambiri kusungunuka ndi zinthu zomaliza. Pewani kugwiritsa ntchito madzi olimba kapena madzi okhala ndi zosafunikira zomwe zingasokoneze kufooka.
Kuyeza ndi kuyeza: Konzani molondola kuchuluka kwa hpmc pogwiritsa ntchito digito. Kukhudzidwa kwa HPMC m'madzi kumasiyana malinga ndi ntchito yomwe mukufuna. Nthawi zambiri, kuchepa kwa 0,1% mpaka 5% w / w ndizambiri pamapulogalamu ambiri.
Gawo la hydration: Kuwaza HPMC pang'onopang'ono komanso mobwerezabwereza pansi pamadzi pomwe zimayambitsa mosalekeza. Pewani kuwonjezera HPMC m'makola akuluakulu kuti muchepetse mapangidwe a zotupa kapena ma applomerates. Lolani hpmc kuti hydrate ndi kufalikira pang'onopang'ono m'madzi.
Kuphatikiza ndi kukakamira: Gwiritsani ntchito zida zosakanikirana zabwino monga maginito, chosakanizira, kapena chosakanizira chachikulu kuti muthandizire kupezeka kwa yunifolomu ya HPMC m'madzi. Khalani ndi zovuta kwambiri kuti muchepetse kuwonongeka kwamphamvu kapena mpweya.
Kuwongolera kutentha: Woyang'anira ndikuwongolera kutentha pa kusungunuka. Nthawi zambiri, kutentha kwa chipinda (20-25 ° C) ndikokwanira kusungunuka hpmc. Komabe, chifukwa cha kusungunuka mwachangu kapena mapangidwe apadera, kutentha kwambiri kungafunike. Pewani kutentha, chifukwa zimatha kunyoza polymer ndipo zimakhudza njira yothetsera vutoli.
Nthawi Yachidziwikire: Kusintha kwathunthu kwa HPMC kumatenga maola angapo, kutengera kalasi, kukula kwa tinthu, kukula kwamphamvu. Pitilizani mosangalatsa mpaka yankho lino limveke, lowoneka bwino, komanso lopanda tinthu tating'ono kapena ma Applomerates.
Kusintha kwa mafa (ngati kuli kofunikira): M'mapangidwe ena, kusintha mafa kungakhale kofunikira kukonza bata ndi magwiridwe antchito a HPMC. Gwiritsani ntchito othandizira oyenera kapena sinthani PH pogwiritsa ntchito asidi kapena zikwangwani malinga ndi zofunikira zina.
Kusefa (ngati kuli koyenera): Atatha kuwonongeka kwathunthu, vaseni njira ya HPMC kudzera pazenera wabwino kapena kusefa pepala kuti muchotse tinthu tating'onoting'ono kapena zosafunikira. Izi zikuwonetsetsa kuti chidziwitso ndi chosankha.
Kusunga ndi kukhazikika: Sungani yankho lokonzekera la HPMC loyera, loyera la mpweya kutali ndi dzuwa komanso kutentha kwambiri. Mayankho osungidwa bwino amakhala osakhazikika kwa nthawi yayitali popanda kusintha kwakukulu pakutulutsa kapena zina.
Zinthu Zomwe Zimakhudza Kuwonongeka kwa HPMC:
Pali zinthu zingapo zomwe zingakhudze kusungunuka ndi zinthu za HPMC:
Kukula kwa tinthu ndi kalasi: Masukulu owoneka bwino a HPMC Shudulwa mosavuta kuposa tinthu tambiri chifukwa chowonjezeka kwambiri chifukwa cha malo othamanga.
Kutentha kwambiri kumathandizira kuti hpmc ikhale itayatsidwa kapena kuwonongeka kwambiri.
Liwiro lokakamira: Kusokonezeka koyenera kumatsimikizira kuti yunifofolomu tifotokozedwe a HPMC ndipo imalimbikitsa kusungunuka mwachangu. Kusokonekera kwambiri kumatha kuyambitsa thovu kapena thovu mu yankho.
Madzi abwino: Madzi abwino omwe amagwiritsidwa ntchito potha kuwonongeka amakhudza kumveka, kukhazikika, komanso mafayilo a HPMC. Madzi oyeretsedwa kapena oyeretsedwa amakopeka kuti achepetse zosayenera ndipo ma ion omwe angasokoneze kuwonongeka.
PH: Ph wa yankho limatha kusintha solubility ndi kukhazikika kwa HPMC. Kusintha pH mkati mwa malo oyenera a HPMC ingakuthandizeni kusinthika ndi ntchito.
Mphamvu ya Ionic: Kukhazikika kwakukulu kwamchere kapena ma ayoni mu njirayi kungasokoneze kuwonongeka kwa HPMC kapena kuwonongeka. Gwiritsani ntchito madzi osankhidwa kapena sinthanitsani mchere womwe ungafunikire.
Shear Afces: Kusakaniza kwamtundu wapamwamba kapena kukonza zinthu kumatha kukhudza nyama ndi magwiridwe antchito a HPMC, makamaka m'mafakitale.
Malangizo osokoneza:
Ngati mukukumana ndi zovuta pakusungunuka hpmc kapena zokumana nazo ndi mtundu wa yankho, lingalirani malangizo otsatirawa:
Kuchulukitsa Kusokonekera: Kuchulukitsa Kusakanikirana mwamphamvu kapena kugwiritsa ntchito zida zosakanikirana zophatikizika kuti zithetsedwe bwino ndi kufalikira kwa HPMC tinthu.
Sinthani kutentha: Thandirani kutentha mkati mwa njira yolimbikitsidwa kuti ithandizire mwachangu popanda kunyalanyaza polymer polymer.
Kuchepetsa kwa tinthu to:
Kusintha kwa Ph: Onani ph ya yankho ndikusintha kuti ndikofunikira kuti mukhalebe oyenera kwambiri kwa HPMC kususuka komanso kukhazikika.
Vuto la madzi: Onetsetsani kuti madzi abwino ndi madzi omwe amagwiritsidwa ntchito pogwiritsa pogwiritsa ntchito njira zoyenerera kapena zoyeretsa.
Kuyesa kwa Kugwirizana: Chitani maphunziro ophatikizika ndi zinthu zina zomwe zingakupangitseni kuyankha kapena kusagwirizana komwe kumakhudza kufalikira.
Funsani malangizo wopanga: Fotokozerani malingaliro ndi malangizo a wopanga ma gamu ya HPMC yokhudza zisudzo, mizu, komanso upangiri wovuta.
Kusungunula hydroxypropyl methylcellulose (hpmc) m'madzi ndi gawo lofunikira mu njira zingapo zamakampani, kuphatikizapo zamankhwala osiyanasiyana, zakudya, zodzoladzola. Mwa kutsatira njira zolimbikitsira ndikuganizira zinthu zazikulu monga tinthu tofanana ndi tinthu tokhalitsa, kutentha, komanso mtundu wa madzi, mutha kukwaniritsa njira yokhazikika ya HPMC yokhala ndi zinthu zokhazikika. Kuphatikiza apo, njira zosokoneza bongo ndi njira zodziwitsira zomwe zingathandize kuthana ndi zovuta ndikuwonetsetsa kuti zinthu zikutha ku HPMC pamapulogalamu osiyanasiyana. Kumvetsetsa kusintha kwa chibadwa ndi zake
Post Nthawi: Mar-09-2024