Hydroxypropyl methyl cellulose ndi carboxymethyl cellulose sodium zitha kusakanikirana

Mutha kusakaniza HPMC ndi CMC

Methyl cellulosendi yoyera kapena yoyera ngati fibrous kapena granular ufa; Zopanda fungo, zosakoma. Izi mankhwala mu madzi kutupa mu bwino kapena pang'ono turbid colloidal njira; Insoluble mu absolute ethanol, chloroform kapena diethyl ether. Imamwazika mwachangu ndikutupa m'madzi otentha pa 80-90 ℃, ndipo imasungunuka mwachangu pambuyo pozizira. Njira yamadzimadzi imakhala yokhazikika kutentha, ndipo imatha kutentha kwambiri, ndipo gel osakaniza amatha kusintha ndi kutentha.

Iwo ali wettability kwambiri, kubalalitsidwa, adhesion, thickening, emulsification, posungira madzi ndi filimu mapangidwe, komanso mafuta impermeability. Kanemayo ali ndi kulimba kwambiri, kusinthasintha komanso kuwonekera. Chifukwa sichikhala cha ionic, chikhoza kukhala chogwirizana ndi ma emulsifiers ena, koma ndi osavuta kutulutsa mchere, ndipo yankho limakhala lokhazikika pamtundu wa PH2 - 12. Sodium carboxymethyl cellulose Mankhwalawa ndi mchere wa sodium wa cellulose carboxymethyl ether, ndi anionic cellulose ether, ndi woyera kapena wamkaka woyera fibrous ufa kapena tinthu, kachulukidwe 0.5-0.7 g/kyubiki centimita, pafupifupi osanunkhiza, osakoma, hygroscopic. Easy kumwazikana m'madzi mandala gelatinous njira, insoluble mu Mowa ndi zina organic solvents.

Pamene pH ya madzi amadzimadzi ndi 6.5 - 8.5, kukhuthala kwa slurry kumachepa kwambiri pamene pH ili> 10 kapena <5, ndipo ntchitoyo ndi yabwino kwambiri pamene pH ili 7. Kukhazikika kwa kutentha, kukhuthala kumakwera mofulumira pansi. 20 ℃, imasintha pang'onopang'ono pa 45 ℃, ndipo mawonekedwe a colloid ndi mamasukidwe akayendedwe ndi katundu amachepetsa kwambiri akatenthedwa kwa nthawi yayitali. pamwamba pa 80 ℃. Mosavuta sungunuka m'madzi, mandala njira; Ndiwokhazikika mu njira ya alkaline, komanso yosavuta kuyiyika ngati asidi. Phindu la pH likakhala 2-3, mvula idzakhalapo, ndipo mvula idzakhalanso ndi mchere wambiri wazitsulo. Hydroxypropyl methyl cellulose, yomwe imadziwikanso kuti hydroxypropyl methyl cellulose, cellulose hydroxypropyl methyl ether, ndikusankhidwa kwa thonje la thonje loyera kwambiri ngati zopangira, pansi pamikhalidwe yamchere mwapadera komanso kukonzekera.

Kusungunuka m'madzi ndi polar C kwambiri ndi gawo loyenera la ethanol / madzi, propanol / madzi, dichloroethane, ndi zina zotero, zosasungunuka mu diethyl ether, acetone, ethanol mtheradi, kutupa m'madzi ozizira kukhala njira yomveka bwino kapena pang'ono ya turbidized colloidal. Njira yothetsera madzi imakhala ndi zochitika zapamtunda, zowonekera kwambiri komanso zokhazikika.Mtengo wa HPMCali ndi katundu wa hot gel. Pambuyo kutentha, mankhwala amadzimadzi njira kupanga gel osakaniza mpweya, ndiyeno amasungunuka pambuyo kuzirala. Kutentha kwa gel osakaniza ndi zosiyana.