Mwachidule za hydroxypypyl methylcellulose (hpmc)

Hydroxypropyl methylcellulose (hpmc)ndi cellulose yopanga cellulose yochokera komanso kupanga polymer pol. Amagwiritsidwa ntchito kwambiri m'mafakitale ambiri monga ntchito yomanga, mankhwala, chakudya, zodzola komanso zokutira. Monga cellulose ya celluse, hpmc imakhala ndi madzi abwino amadzi, mawonekedwe a makanema, zomatira ndi emulsization, motero ali ndi phindu lofunikira m'magawo ambiri.

1. Kapangidwe ka mankhwala ndi katundu wa HPMC

Kupanga kwa masentimita kwa HPMC kumachokera ku cellulose wachilengedwe. Pambuyo mankhwala, methyl (-och₃) ndi hydroxypropyl (-och₂ch₂oh amayambitsidwa mu unyolo wapanjala. Kapangidwe kake kolimba kuli motere:

Cellulose mamolekyulu amapangidwa ndi mayunitsi a glucose olumikizidwa ndi β-1,4-Glycosidic;

Magulu a methyl ndi hydroxypyl amayambitsidwa mu cellulose utatu kudzera mu zomwe zimachitika.

Kapangidwe ka mankhwala kumeneku kumapereka hpmc zotsatirazi:

Kusungunuka kwamadzi: Mwa kuwongolera digiri ya kulowetsedwa kwa methyl ndi ma hydroxypyl m'magulu, hpmc imatha kusintha madzi ake kususuka. Nthawi zambiri, kuwerengako kwa HPMC kumatha kupanga njira yothetsera ma viscous m'madzi ozizira ndipo imakhala ndi madzi abwino.

Kusintha kwa Viscty: Makulidwe a HPMC ikhoza kulamuliridwa moyenera ndikusintha kulemera ndi kuchuluka kwa cholowa chazolowa kuti akwaniritse zofunika kugwiritsa ntchito.

Kutsutsa Kwamoto

Zoyenera: hpmc ndi zinthu zosafunikira komanso zosasangalatsa, motero imakondedwa kwambiri mu gawo lazachipatala.

2. Njira yakukonzekera ya HPMC

Njira yokonzekera ya HPMC imatsirizidwa makamaka yomwe imachitika chifukwa cha cellulose. Malingaliro ake ali motere:

Cellulose zosungunulira: Choyamba, sakanizani cellulose ndi zosungunulira (monga chloroform (monga chloroform, zosungunulira mowa, etc.) kupatsa yankho la cellulose.

Kusintha kwamankhwala: methyl ndi hydroxypropyl mankhwala (monga chloromethyl mankhwala ndi mowa woledzera) amawonjezeredwa ku njira yobweretsera.

Kulowerera ndi kuyanika: Mtengo wa pH umasinthidwa ndi kuwonjezera acid kapena alkali, ndi kulekanitsa, kuyera ndi kuwuma kumachitika pambuyo pake methylcellulose.

3. Ntchito zazikulu za HPMC

Malo apadera a Hopmc amagwiritsidwa ntchito kwambiri m'minda yambiri. Otsatirawa ndi ena mwa madera akulu ogwiritsa ntchito:

. Itha kukonza madzi, kutsatsa ndi kusungira kwamadzi kwa osakaniza. Makamaka pamatamba owuma, hpmc imatha kukonza magwiridwe antchito, onjezerani chomata cha matope, ndikupewa ming'alu mu simenti slurry panthawi yolimba.

. Monga wothandizira makanema, Thickener ndi kukhazikika, zimatha kusintha kusungunuka ndi bioavailat kwa mankhwala. M'mapiritsi, HPMC singangolamulira kuti amasulidwe mankhwala osokoneza bongo, komanso kukonza mankhwala osokoneza bongo.

. Mwachitsanzo, zakudya zochepa komanso zoperewera, hpmc zimatha kupereka kukoma komanso kapangidwe kake ndikuwonjezera kukhazikika kwa chinthucho. Amagwiritsidwanso ntchito kwambiri pazomwe zimapangitsa kuti mpweya uletse madzi kapena mapangidwe a Ice Crastal.

. Zimatha kusintha kapangidwe ka zodzola, kupangitsa kuti azitha kugwiritsa ntchito ndi kuyamwa. Makamaka pakhungu la khungu, shampoos, nkhope ya nkhope ndi zinthu zina, kugwiritsa ntchito HPMC kumatha kusintha malingaliro ndi kukhazikika kwa malonda.

. Zimathandizanso kuthetsa madzi ndi mayanjano ovomerezeka, ndikuwonjezera kuuma ndi kutsatira kwa zokutira.

4. Chiyembekezo cha msika ndi zochitika za HPMC

Anthu akamamvetsera mwachidwi chilengedwe komanso thanzi, hpmc, monga zinthu zobiriwira komanso zosafunikira, zimakhala ndi chiyembekezo. Makamaka mu mankhwala opangira mankhwala, chakudya ndi zodzikongoletsera, kugwiritsa ntchito HPMC kudzawonjezeredwanso. M'tsogolomu, kupanga kwa HPMC kumayenera kuthandizidwanso, ndipo kuchuluka kwake ndikuchepetsa mtengo kumapangitsa kuti ntchito yake ikhalepo.

Ndi chitukuko cha zinthu zanzeru komanso ukadaulo wolamulidwa, kugwiritsa ntchito HPMC mu SMARY Systems kubwerezedwanso kudzakhalanso hotspot. Mwachitsanzo, HPMC itha kugwiritsidwa ntchito kukonza zonyamula zamankhwala zomwe zimayendetsedwa ndi ntchito yomasulidwa kuti zipitirire kutalika kwa mankhwalawa komanso kukonza bwino.

Hydroxypypyl methylcellulosendi zinthu za polymer ndi ntchito yabwino kwambiri komanso kugwiritsa ntchito kwakukulu. Ndi kusungunuka kwamadzi abwino kwambiri, kuthekera kosasintha ma viscction ndi zinthu zabwino, hpmc kuli ndi ntchito zofunika m'magawo ambiri monga ntchito za HPMC zitha kupitiriza kukula, ndipo chiyembekezo chakomwe chimakhala chokulirapo.