Hydroxypropyl methylcellulose (hpmc) ndi polymer yosiyanasiyana yogwiritsidwa ntchito kuyambira m'mafakitale ochokera ku mankhwala omanga mankhwala kuti azimanga chifukwa cha zovuta zake. Ndizosasinthika kwa ma cellulose, omwe ali ndi magulu a hydroxyl adasinthidwa ndi magulu a methoxypyl ndi hydroxypyl, akulimbika kususuka kwake m'madzi ndi ena osungunulira.
Makhalidwe osinthasintha a HPMC
1. Madzi osungunuka
HPMC imasungunuka nthawi zambiri. Kusungunuka kwake m'madzi kumayendetsedwa ndi zinthu zingapo:
Kutentha: HPMC imasungunuka mu madzi ozizira kapena otentha. Mukatenthetsa, hpmc imatha kupanga gel; Pa zozizira, gel imasungunuka kachiwiri, ndikupangitsa kuti zisinthe. Mafuta amoto awa ndi othandiza pantchito monga mankhwala owongolera mankhwala ogulitsa mankhwala.
Kukhazikika: Zotsika zotsika (0,5-2%) nthawi zambiri zimasungunuka mosavuta. Kukhazikika kwamphamvu (mpaka 10%) kungafunike kulimbikira komanso nthawi.
PH: HPMC Mayankho ndi okhazikika pamafayilo osiyanasiyana (3-11), kuwapangitsa kukhala mosiyanasiyana mosiyanasiyana.
2. Zaukadaulo
Ngakhale osungunuka madzi osungunuka, hpmc amathanso kusungunuka mu ma soric sormic, makamaka iwo omwe ali ndi polar. Izi ndi monga:
Mowa: HPMC imawonetsa kusandulika kwabwino mu mowa wocheperako ngati methanol, ethanol, ndi isoppanol. Mankhwala apamwamba sagwira bwino ntchito chifukwa cha maunyolo awo a hydrophobic.
Glycols: Propylene glycol ndi polyethylene glycol (msomali) amatha kusungunula hpmc. Izi zosungunulira nthawi zambiri zimagwiritsidwa ntchito kuphatikiza ndi madzi kapena mowa kuti musinthe kusungunuka komanso kusakhazikika.
Malaji: Malo ena a Acetone ndi methyl ethyl ketone amatha kusungunula hpmc, makamaka mukasakanizidwa ndi madzi.
3. Zosakaniza
HPMC imathanso kusungunuka muzovuta zosungunulira. Mwachitsanzo, kuphatikiza madzi ndi mowa kapena glycols amatha kukulitsa kusumulili. The Syrnergy pakati pa ma sol solt imatha kutsitsa ndende imodzi yokhayo, kutsanulira zisudzo.
Makina osungunuka
Kufalikira kwa HPMC mu ma solfs kumaphatikizapo kuphwanya magulu azolowera pakati pa HPMC kunyolo ndi kupanga njira zatsopano zokhala ndi mamolekyulu osungunulira. Zinthu zomwe zimapangitsa kuti izi zikuphatikiza:
Kuphatikizira Hydrogen: HPMC kumamtundu hydrogen ndi madzi ndi polars zina polar, kuwongolera kusungunuka.
Kulumikizana kwa Polyment: Kutha kwa mamolekyulu kuti alowemo ndikuyanjana ndi maunyolo a HPMC kumakhudza kupezeka kofatsa.
Makina Kukakamizidwa: Kuyambitsa kumathandizira kuthana ndi okalamba ndikulimbikitsa kusinthika.
Malingaliro othandiza kuti asungunuke hpmc
1. Njira Yopumira
Kuti zisungunuke bwino, tsatirani izi:
Zowonjezera pang'onopang'ono: Pang'onopang'ono onjezani HPMC kwa HPMC ku Swevent ndi kusunthira kosalekeza kuti mupewe.
Kuwongolera kutentha: Sungunulani HPMC m'madzi ozizira kupewa kufalikira kosatha. Kwa ena okhazikika, kutentha pang'ono kungathandize.
Njira Zosakanikirana:
2. Kuzindikira ndi mafayilo
Kukhazikika kwa HPMC kumakhudza mafayilo a yankho:
Ndende yotsika: imapangitsa kuti muchepetse njira yotsika kwambiri, yoyenera kugwiritsa ntchito zokutira kapena kumanga.
Kukhazikika kwakukulu: kumapangitsa yankho lalitali kapena gel, zothandiza pakupanga mankhwala omasulidwa.
3. Kugwirizana
Mukamagwiritsa ntchito HPMC mu kapangidwe ka HPMC, onetsetsani kuti kugwirizana ndi zosakaniza zina:
Khalidwe lokhazikika: Tsimikizirani kuti zigawo zina sizisintha pH kupitirira malo okhazikika a HPMC.
Kukhuta Kutentha: Ganizirani katundu wam'madzi akamapanga njira zosinthira kutentha.
Mapulogalamu a HPMC mayankho
Mayankho a HPMC amagwiritsidwa ntchito pa mafakitale osiyanasiyana chifukwa cha malo awo apadera:
1. Mankhwala
HPMC imagwira ngati bander, filimu wakale, ndi wolamulira wowongolera:
Mapiritsi ndi makapisozi: Mayankho a HPMC amathandizira pakumanga zosakaniza ndikupanga mafilimu owongolera mankhwala osokoneza bongo.
Ma gels: Amagwiritsidwa ntchito pazosintha zapamwamba chifukwa cha kukula kwake komanso kulimbitsa katundu.
2. Makampani azakudya
Monga chakudya chowonjezera, hpmc imagwiritsidwa ntchito pokhazikika komanso kutulutsa zinthu:
Otsatsa: Amasintha mawonekedwe ndi kukhazikika m'misuzi ndi zovala.
Mapangidwe a makanema: amapanga mafilimu okhazikika a zokutira ndi matembenuzidwe.
3. Ntchito
Mayankho a HPMC amalimbikitsa katundu womanga:
Simenti ndi matope: Kugwiritsidwa ntchito ngati thunthu losunga madzi muzogulitsa za simenti.
Utoto ndi zokutira: Zimapereka chiwongolero cha rhelogical komanso kukhazikika mu utoto.
Kupambana Kwabwino Kwambiri
1. Ultrasonication
Kugwiritsa ntchito mafunde akupanga kuti asungunuke hpmc kumatha kukulitsa muyeso wa kuwonongeka ndikuphwanya tinthu tambiri ndikulimbikitsa kupezeka kwa yunifolomu.
2. Kusakaniza kwakukulu
Zosakaniza zazitali kwambiri zimapangitsa kusakanikirana kwakukulu, kuchepetsa nthawi yozizira ndikuwongolera homogeneransi, makamaka m'mawu a mafayilo apamwamba.
Maganizo a chilengedwe ndi chitetezo
1. Biodegradiity
HPMC ndi biodegradgle, ndikupangitsa kuti zikhale ochezeka. Amasokoneza zigawo zachilengedwe, kuchepetsa chilengedwe.
2. Chitetezo
HPMC siyopanda poizoni komanso yotetezeka kuti mugwiritse ntchito mu chakudya, mankhwala ogulitsa, komanso zodzoladzola. Komabe, mapepala osungira deta (SDS) ayenera kuwunikiridwa kuti agwirizanitse ndi kuwongolera malangizo.
Kusungunula HPMC kumafuna kumvetsetsa mawonekedwe ake osinthana ndi kutumiza ndi ma sol sol. Madzi amakhalabe zosungunulira koyamba, pomwe mowa, glycols, ndi zosinthika zosungunulira zimapatsa njira zina zothandizira kugwiritsa ntchito njira zina. Njira zoyenera ndi malingaliro oyenera kutsimikizira kuti chitumbundikiro bwino, pokonzanso HPMC's Voteranile kugwiritsa ntchito mafakitale.
Post Nthawi: Jun-14-2024