Kusankha koyenera kwa hydroxypropyl methylcellulose

Hydroxypropyl methylcellulose (hpmc) ndi polymer yosiyanasiyana yomwe imagwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana chifukwa chazinthu zake zapadera. Monga cellulose yochokera ku cellulose ya chilengedwe ndipo ili ndi hydroxypyll ndi methyl magulu omwe amaphatikizidwa ndi msana wa m'Chunji. Kusintha kumeneku kumapereka katundu wabwino, kupangitsa kuti ndikoyenera kugwiritsa ntchito mitundu yosiyanasiyana, kuphatikizapo zamankhwala, kuphatikiza, chakudya, ndi zinthu zosamalira pandekha.

Kusankha kalasi yoyenera ya HPMC ndikofunikira kuti mukwaniritse zomwe mukufuna. Pali zinthu zingapo zomwe zimathandizira kusankha kwa HPMC, kuphatikiza ma visct, methoxy ndi hydroxypyl, cholowa m'malo, komanso kukula kwa tinthu. Pokambirana izi, tionana bwino zinthu izi ndikufufuza momwe zimakhudzira kusankha kwa HPMC pa ntchito zosiyanasiyana.

1. Makutu:

Chimodzi mwazomwe zimaganizira kwambiri mukamasankha hpmc ndi mawonekedwe ake. Ma viscCon amatanthauza kukana kwamadzi kuti atuluke. Ku HPMC, ma virus ndi muyeso wa makulidwe kapena kusasinthika kwa yankho. OsiyanaNtchito zofunsira zimafunikira ma vinya osiyanasiyana a HPMC. Mwachitsanzo:

Mankhwala opangira mankhwala: M'mapangidwe a mankhwala opangira mankhwala, hpmc nthawi zambiri amagwiritsidwa ntchito ngati wothandizila komanso wowonjezera. Kusankha kwa kalasi ya mafayilo kumadalira kapangidwe kake kazinthu komaliza, kaya mapiritsi, makapisozi kapena mapangidwe amadzimadzi.

Ntchito Zomanga: M'malo omanga, hpmc imagwiritsidwa ntchito kwambiri mu matope osakanikirana. Makulidwe a HPMC amakhudzanso kusungidwa kwamadzi, kugwirira ntchito komanso kukana kwa matope. Ntchito zoyezera nthawi zambiri zimakonda kusintha kwa ma vincy kuti mupewe sag.

2. Methoxy ndi hydroxypropyl:

Mlingo wa zolowa m'malo mwa HPMC amatanthauza kuchuluka kwa minitsi ya hydroxypyl ndi methoxy magulu a cellulose kwambiri ndipo ndi chinthu chofunikira. Makhalidwe osiyanasiyana a DS akhoza kutsogolera to Kusintha mu kusungunuka, khwala, ndi zina. Kuganizirana kumaphatikizapo:

Makanema filimu mu ma garmaceuticals: hpmc yokhala ndi minda ya methoxyl nthawi zambiri amakonda zokutira filimu m'malo mwa mafilimu chifukwa chimachepetsaKuchita bwino zachilengedwe.

3. Mtundu wina:

Mtundu wolowa nawo ndi chinthu china chofunikira kwambiri. HPMC imatha kusungunuka mwachangu (yotchedwanso "mwachangu") kapena kusungunuka pang'onopang'ono. Kusankha kumatengera mbiri yomasulidwa yomwe imafunikira mu mankhwala a mankhwala. Mwachitsanzo:

Mapulogalamu omasulidwa: Kuwongolera mapangidwe omasulidwa, osungunuka pang'onopang'ono a HPMC angakonde kuti akwaniritse kumasulidwa kwa ingrmaceusticalwodekha.

4. Kukula kwa tinthu:

Kukula kwa tinthu kumakhudza kubalalitsidwa ndi kusungunuka kwa HPMC mu yankho. Tinthu tating'onoting'ono timakonda kusungunuka mosavuta, zimakhudzanso magwiridwe antchito osiyanasiyana:

Makampani ogulitsa zakudya: m'makampani azakudya, hpmc amagwiritsidwa ntchito pantchito monga kukula ndi kukhazikika. Mbewu ZabwinoEd hpmc nthawi zambiri amakonda kukoma mtima kwake ndikubalalitsa katundu pakupanga zakudya.

5. Kugwirizana ndi Zosakaniza Zina:

Kufanana kwa hpmc ndi zosakaniza zina pakupanga ndikofunikira pakuchita kwake. Izi zikuphatikiza kufanana ndi zopangira zam'madzi zopangira (apis) mu mankhwala kapena kuphatikizidwa ndi zina zowonjezera m'matongani.

Zogulitsa zamankhwala: HPMC iyenera bEN yogwirizana ndi API kuti muwonetsetse bata ndi kuphatikiza yunifolomu mkati mwa mawonekedwe.

6. Kutsatira lamulo:

Kwa mapulogalamu ogulitsa mankhwala ndi zakudya, kutsatira malangizo oyang'anira ndikofunikira. Kalasi ya HPMC yosankhidwa iyenera kutsatira mankhwala oyenerera kapena owonjezera chakudya.

Mankhwala osokoneza bongo ndi chakudya: Kugwirizana ndi miyezo ya Condial (mwachitsanzo, USP, EP, JP) kapena chakudya chowonjezeraNS (mwachitsanzo, malamulo a FDa) ndiwofunikira kuti atsimikizire chitetezo ndi kugwira ntchito.

7.

Mtengo umaganizira za ntchito iliyonse ya mafakitale. Mukamasankha kalasi yoyenera ya HPMC, kugwirizanitsa zofuna za magwiridwe antchito ndi zomwe zimafuna ndalama ndizovuta.

Makampani omanga: M'makampani omanga, hpmc amagwiritsidwa ntchito kwambiri pamapangidwe osakaniza osakaniza, pomwe mphamvu ndi yofunika kwambiri.

Kusankhidwa koyenera kwa hydroxypropyl methylcellulose kumafuna kuganizira zinthu zosiyanasiyana, kuphatikizapo mtundu wake, kukula ndi zosakaniza zina, kutsatana ndi mtengo. Kugwiritsira ntchito kulikonse kuli ndi zofunikira zina, ndikusankha kalasi yoyenera ya HPMC kumatsimikizira ntchito zoyenera komanso zomwe mukufuna. Ndikulimbikitsidwa kugwira ntchito ndi othandizira ndi opanga omwe angapereke thandizo ndi chitsogozo chakukuthandizani kusankha njira ya HPMC yoyenereradi pulogalamu yanu.