Makhalidwe a viscosity ya hydroxypropyl methylcellulose yankho lamadzi

 Hydroxypropyl methylcellulose (HPMC) ndi non-ionic madzi sungunuka cellulose ether kwambiri ntchito yomanga, mankhwala, chakudya, zodzoladzola ndi mafakitale mankhwala. Makhalidwe a viscosity ya yankho lamadzimadzi ndizinthu zazikulu zomwe zimakhudza ntchito yake yogwiritsira ntchito.

1. Makhalidwe oyambira a HPMC

AnxinCel®HPMC ndi chochokera ku cellulose chopangidwa poyambitsa magulu a hydroxypropyl ndi methyl mu unyolo wa cellulose. Ili ndi kusungunuka kwamadzi bwino komanso kukhuthala kwambiri, ndipo nthawi zambiri imagwiritsidwa ntchito popanga njira zamadzimadzi zomwe zimakhala ndi ma rheological properties. Makhalidwe amenewa kupanga HPMC chimagwiritsidwa ntchito zokutira, zomatira, mankhwala kupitiriza kumasulidwa, zina chakudya ndi mafakitale ena.

2. Makhalidwe a viscosity ya HPMC yamadzimadzi yothetsera

Makhalidwe a viscosity ya HPMC yamadzimadzi amakhudzidwa ndi zinthu zingapo, makamaka kuphatikiza ndende, kutentha, kumeta ubweya, mtengo wa pH ndi kapangidwe ka maselo.

Zotsatira za ndende pa mamasukidwe akayendedwe

The mamasukidwe akayendedwe a HPMC amadzimadzi njira kumawonjezeka ndi kuwonjezeka ndende. Pamene ndende ya HPMC ndi otsika, njira amadzimadzi ndi woonda ndi otsika mamasukidwe akayendedwe; pamene ndende ikuwonjezeka, kuyanjana pakati pa mamolekyu kumawonjezeka, ndipo kukhuthala kwa njira yamadzimadzi kumawonjezeka kwambiri. Kawirikawiri, mamasukidwe amphamvu a HPMC amagwirizana kwambiri ndi ndende yake, koma amakhala okhazikika pamagulu enaake, kusonyeza maonekedwe a viscosity ya yankho.

Mmene kutentha pa mamasukidwe akayendedwe

Kutentha ndi chinthu chofunikira chomwe chimakhudza kukhuthala kwa AnxinCel®HPMC yankho lamadzi. Pamene kutentha kumakwera, zomangira za haidrojeni ndi kuyanjana kwa hydrophobic mu mamolekyu a HPMC zidzafooketsa, zomwe zimapangitsa kuchepa kwa mphamvu yomanga pakati pa mamolekyu, motero kuchepetsa kukhuthala kwa njira yamadzimadzi. Nthawi zambiri, mamasukidwe amadzimadzi a HPMC amawonetsa kutsika kwakukulu komwe kumatsika ndikuwonjezeka kwa kutentha, makamaka pakutentha kwakukulu. Izi zimapangitsa HPMC kukhala ndi luso lowongolera bwino pamapulogalamu ena owongolera kutentha.

Zotsatira za kumeta ubweya wa ubweya pa mamasukidwe akayendedwe

HPMC amadzimadzi njira limasonyeza mmene Newtonian madzimadzi makhalidwe pa otsika kukameta ubweya mitengo, ndiko kuti, mamasukidwe akayendedwe ndi wokhazikika; komabe, pamiyeso yayikulu yometa ubweya, kukhuthala kwa njira ya HPMC kudzachepa kwambiri, kuwonetsa kuti ili ndi kumeta ubweya wa ubweya. Mamolekyu a HPMC ali ndi zinthu zina za rheological. Pamiyeso yotsika yometa ubweya, maunyolo a molekyulu amapindika kwambiri, ndikupanga kukana kwamapangidwe apamwamba, komwe kumawonetsedwa ngati mawonekedwe apamwamba; pamiyeso yayikulu yometa ubweya, unyolo wa mamolekyu umakonda kutambasula, madzimadzi amawonjezeka, ndipo kukhuthala kumachepa.

Zotsatira za mtengo wa pH pa viscosity

HPMC amadzimadzi njira zambiri amakhala ndi khola mamasukidwe akayendedwe pansi ndale ndi ofooka zinthu zamchere. M'malo olimba a asidi kapena amphamvu, mamolekyu a HPMC amatha kukumana ndi protonation kapena deprotonation reactions, zomwe zimapangitsa kusintha kwa hydrophilicity, hydrophobicity ndi intermolecular interactions pakati pa mamolekyu, motero zimakhudza kukhuthala kwa njira yamadzimadzi. Muzochitika zodziwika bwino, kusintha kwa pH sikukhudzidwa pang'ono ndi kukhuthala kwa mayankho a HPMC, koma pansi pa zovuta za pH, kusintha kwa viscosity kungakhale koonekeratu.

Zotsatira za kapangidwe ka maselo pa viscosity

Mawonekedwe a viscosity a HPMC amagwirizana kwambiri ndi kapangidwe kake ka maselo. Kuchuluka kwa kusintha kwa magulu a hydroxypropyl ndi methyl mu molekyulu kumakhudza kwambiri kukhuthala kwa njira yamadzi. The apamwamba digiri ya m'malo gulu, wamphamvu hydrophilicity wa HPMC ndi apamwamba mamasukidwe akayendedwe a yankho. Kuphatikiza apo, kulemera kwa maselo a HPMC ndichinthu chofunikira kwambiri chomwe chimakhudza kukhuthala kwake. Kulemera kwa ma molekyulu, kutalika kwa unyolo wa mamolekyu, ndi kuyanjana kwamphamvu pakati pa ma molekyulu, zomwe zimapangitsa kuti madzi amadzimadzi aziwoneka bwino.

3. Kufunika kwa mawonekedwe a mamasukidwe akayendedwe a HPMC amadzimadzi njira ntchito

Makhalidwe a viscosity ya HPMC yamadzimadzi ndiyofunikira kuti igwiritsidwe ntchito m'magawo osiyanasiyana.

Munda womanga: HPMC imagwiritsidwa ntchito nthawi zambiri mumatope a simenti ndi zomatira, ndipo imakhala ndi ntchito zokulitsa, kusunga chinyezi, ndikuwongolera ntchito yomanga. Makhalidwe ake mamasukidwe akayendedwe mwachindunji zimakhudza workability ndi adhesion wa matope. Posintha ndende ndi mamolekyu a HPMC, ma rheological properties a matope amatha kuwongoleredwa, potero kumapangitsa kuti zomangamanga zikhale zosavuta.

Makampani opanga mankhwala: AnxinCel®HPMC njira yamadzimadzi nthawi zambiri imagwiritsidwa ntchito pokonzekera monga mankhwala osasunthika, zipolopolo za kapisozi, ndi madontho a maso. Makhalidwe ake a viscosity angakhudze kutulutsidwa kwa mankhwala ndikuwongolera kutulutsidwa kwa mankhwala m'thupi. Posankha HPMC yokhala ndi kulemera koyenera kwa maselo ndi kuchuluka kwa kulowetsedwa m'malo, mawonekedwe otulutsa mankhwala amatha kusinthidwa kuti akwaniritse zochiritsira zenizeni.

Makampani azakudya: HPMC imagwiritsidwa ntchito ngati thickener, stabilizer, ndi emulsifier pokonza chakudya. The mamasukidwe akayendedwe makhalidwe ake amadzimadzi njira zimakhudza kukoma ndi bata la chakudya. Posintha mtundu ndi kuchuluka kwa HPMC yogwiritsidwa ntchito, mawonekedwe a chakudya amatha kuyendetsedwa bwino.

Makampani opanga zodzoladzola: HPMC, monga thickener ndi stabilizer mu zodzoladzola, akhoza kusintha kapangidwe ka mankhwala, kuwapatsa fluidity yoyenera ndi kumva bwino. Mawonekedwe ake a viscosity amakhudza kwambiri momwe amagwiritsira ntchito zinthu monga zonona, ma gels, ndi ma shampoos.

Makhalidwe a mamasukidwe akayendedwe aMtengo wa HPMC mayankho amadzimadzi amakhudzidwa ndi zinthu zambiri monga ndende, kutentha, kumeta ubweya, mtengo wa pH, ndi kapangidwe ka maselo. Posintha zinthu izi, magwiridwe antchito a HPMC amatha kukonzedwa kuti akwaniritse zosowa zamafakitale osiyanasiyana chifukwa cha rheological properties. Kafukufuku wozama pa mawonekedwe a viscosity a HPMC mayankho amadzimadzi sikuti amangothandiza kumvetsetsa zoyambira zake, komanso amapereka chitsogozo chamalingaliro pakugwiritsa ntchito kwake pakupanga kwenikweni.