Maphunziro a Rheological of Hydroxypropyl Methylcellulose (HPMC) thickener system ndi ofunikira kuti amvetsetse momwe amagwirira ntchito zosiyanasiyana, kuyambira mankhwala mpaka zakudya ndi zodzola. HPMC ndi chotumphukira cha cellulose ether chomwe chimagwiritsidwa ntchito ngati thickening agent, stabilizer, ndi emulsifier chifukwa cha kuthekera kwake kusintha mawonekedwe a rheological a mayankho ndi kuyimitsidwa.
1. Kuyeza kwa Viscosity:
Viscosity ndi imodzi mwazinthu zofunika kwambiri za rheological zomwe amaphunzira mu machitidwe a HPMC. Njira zosiyanasiyana monga rotational viscometry, capillary viscometry, ndi oscillatory rheometry amagwiritsidwa ntchito poyeza kukhuthala.
Maphunzirowa amawunikira zotsatira za zinthu monga ndende ya HPMC, kulemera kwa maselo, kuchuluka kwa m'malo, kutentha, ndi kumeta ubweya wa ma viscosity.
Kumvetsetsa mamasukidwe akayendedwe ndikofunikira chifukwa kumatsimikizira kayendedwe ka kayendedwe kake, kukhazikika, komanso kukwanira kwa machitidwe a HPMC.
2.Makhalidwe Owonda:
Mayankho a HPMC nthawi zambiri amawonetsa kumeta ubweya wa ubweya, kutanthauza kukhuthala kwawo kumachepa ndi kuchuluka kwa kumeta ubweya.
Maphunziro a Rheological amayang'ana pakukula kwa kumeta ubweya wa ubweya komanso kudalira kwake pazinthu monga ndende ya polima ndi kutentha.
Kuzindikiritsa kumeta ubweya wa ubweya ndikofunikira pakugwiritsa ntchito monga zokutira ndi zomatira, komwe kumayenda panthawi yakugwiritsa ntchito komanso kukhazikika pambuyo pakugwiritsa ntchito ndikofunikira.
3.Thixotropy:
Thixotropy amatanthauza kubwezeretsedwa kwa nthawi yodalira mamasukidwe akayendedwe pambuyo pochotsa kupsinjika kwa shear. Ambiri HPMC kachitidwe amasonyeza thixotropic khalidwe, amene ndi opindulitsa ntchito amafuna ankalamulira otaya ndi bata.
Maphunziro a Rheological amaphatikizapo kuyeza kubwezeretsedwa kwa mamasukidwe akayendedwe pakapita nthawi pambuyo poyambitsa kumeta ubweya wa dongosolo.
Kumvetsetsa zothandizira thixotropy popanga zinthu monga utoto, komwe kukhazikika panthawi yosungira komanso kugwiritsa ntchito mosavuta ndikofunikira.
4. Gelation:
Pamalo okwera kwambiri kapena zowonjezera zina, mayankho a HPMC amatha kukhala ndi ma gelation, ndikupanga maukonde.
Kafukufuku wama Rheological amafufuza momwe ma gelation amakhalira pazinthu monga ndende, kutentha, ndi pH.
Maphunziro a Gelation ndi ofunikira pakupanga mankhwala otulutsidwa mosalekeza ndikupanga zinthu zokhazikika zokhala ndi gel m'mafakitale azakudya ndi chisamaliro chamunthu.
5. Makhalidwe Apangidwe:
Njira monga kufalikira kwa X-ray (SAXS) ndi rheo-SAXS zimapereka chidziwitso pa microstructure ya machitidwe a HPMC.
Maphunzirowa amawulula zambiri zokhudzana ndi ma polymer chain conformation, machitidwe ophatikizana, komanso kuyanjana ndi mamolekyu osungunulira.
Kumvetsetsa momwe zimapangidwira kumathandizira kulosera za machitidwe a macroscopic rheological ndikuwongolera mapangidwe azinthu zomwe mukufuna.
6.Dynamic Mechanical Analysis (DMA):
DMA imayesa ma viscoelastic azinthu zomwe zili pansi pa oscillatory deformation.
Maphunziro a Rheological pogwiritsa ntchito DMA amawunikira magawo monga modulus yosungirako (G'), losse modulus (G"), ndi kukhuthala kovutirapo monga ntchito ya pafupipafupi komanso kutentha.
DMA ndiyothandiza makamaka pozindikiritsa machitidwe olimba ngati amadzimadzi a HPMC gels ndi phala.
7.Kafukufuku Wachindunji:
Maphunziro a Rheological amapangidwa kuti azigwiritsidwa ntchito mwapadera monga mapiritsi amankhwala, pomwe HPMC imagwiritsidwa ntchito ngati chomangira, kapena muzakudya monga sosi ndi mavalidwe, pomwe imagwira ntchito ngati thickener ndi stabilizer.
Maphunzirowa amakonza mapangidwe a HPMC kuti azitha kuyenda bwino, mawonekedwe ake, komanso kukhazikika kwa shelufu, kuwonetsetsa kuti zinthu zikuyenda bwino komanso kuvomerezedwa ndi ogula.
maphunziro a rheological amatenga gawo lofunikira pakumvetsetsa zovuta za machitidwe a HPMC thickener. Mwa kufotokoza mamasukidwe akayendedwe, kukameta ubweya wa ubweya, thixotropy, gelation, structural properties, and application-Specific properties, maphunzirowa amathandizira kamangidwe ndi kukhathamiritsa kwa HPMC-based formulations m'mafakitale osiyanasiyana.
Nthawi yotumiza: May-10-2024