Hpmc (hydroxypropyl methylcellulose) ndi malo osungunuka osungunuka osungunuka omwe amagwiritsidwa ntchito mu mankhwala ogulitsa, chakudya, zomangamanga, zodzoladzola komanso mafakitale ena. HPMC ndi mankhwala opaka celluse omwe amapezeka ndi kusinthidwa kwamankhwala kwa cellulose wachilengedwe, ndipo nthawi zambiri amagwiritsidwa ntchito ngati thiCerner, ritsebilite, emulsifier komanso zomata.
Katundu wa hpmc
Malo osungunuka a hpmc amakhala ovuta kwambiri chifukwa malo ake osungunuka sawonekeranso monga momwe zidaliriri za makhrirstalline. Mfundo yake yosungunuka imakhudzidwa ndi kapangidwe kake, kulemera kwa maselo ndi digiri yam'mimba ya hydroxypyl ndi magulu a methyl, motero imatha kukhala yosiyanasiyana malingana ndi zinthu zina za HPMC. Nthawi zambiri, monga polymer yosungunuka yamadzi, hpmc ilibe malo osungunuka komanso yunifolomu, koma imafewetsa ndikuwola mkati mwa kutentha kwina.
Malo osungunuka
Mafuta owonera matenda a nkhawa ®hpmc amakhala wovuta kwambiri, ndipo kuwonongeka kwake kwamafuta nthawi zambiri kumaphunziridwa ndi thermagravimetric discy (TGA). Kuchokera pamabuku, imatha kupezeka kuti malo osiyanasiyana osungunuka a HPMC ali pakati pa 200°C ndi 300°C, koma mitundu iyi siyiyimira malo osungunuka a HPMC yonse. Mitundu yosiyanasiyana ya zinthu za HPMC imatha kukhala ndi mfundo zosiyanasiyana zosungunuka ndi zinthu zomwe zimakhala ndi ma celeculations olemera, digiri yazolowa m'malo mwa hydroxypropropropropropropropropsy (mulingo wazolowa).
Kulemera pang'ono kwa Hopmc: Nthawi zambiri amasungunuka kapena kufewetsa kutentha kochepa, ndipo amatha kuyamba pyrolyze kapena kusungunuka pafupifupi 200°C.
Kulemera kwambiri kwa HPMC: HPMC Ma Polics okhala ndi zolemetsa zapamwamba zingafunike kutentha kwambiri kuti musungunuke kapena kufewetsa chifukwa cha unyolo wawo, ndipo nthawi zambiri amayamba kututa ma molecular ndi kusungunuka pakati pa 250°C ndi 300°C.
Zinthu zomwe zikukhudza malo osungunuka a hpmc
Kulemera kwa maselo: Kuchepetsa thupi kwa HPMC kumakhudza kwambiri mfundo yake yosungunuka. Kulemera kwam'munsi nthawi zambiri kumatanthawuza kutentha kosungunuka, pomwe kulemera kwambiri kwa molecular kungayambitse malo okwera.
Ma digiri ya zolowa: Mlingo wa hydroxypropropys (mwachitsanzo, kuchuluka kwa hydroxypyl) ndi digiri ya methyl (nee Centrio ya methyl imakhudzanso malo ake osungunuka. Nthawi zambiri, kuchuluka kwa cholowa kumapangitsa kusungunuka kwa HPMC ndikuchepetsa malo ake osungunuka.
Zolemba: Monga zinthu zosungunulira madzi, malo osungunuka a HPMC amakhudzidwanso ndi chinyezi chake. HPMC yokhala ndi chinyontho chonyowa kwambiri amatha kupweteka kapena kusungunuka pang'ono, zomwe zimapangitsa kuti musinthe kutentha kwa mafuta.
Kukhazikika kwamafuta ndi kutentha kwa HPMC
Ngakhale HPMC ilibe malo okhazikika, kukhazikika kwake kwamphamvu ndi chizindikiro chofunikira kwambiri. Malinga ndi kusanthula kwa thermagravimetric (tga), hpmc nthawi zambiri kumayamba kuwola mu kutentha kwa 250°C mpaka 300°C. Kutentha kwina kumadalira kulemera kwa maselo, kuchuluka kwa kuloweza ndi zinthu zina zakuthupi ndi mankhwala a HPMC.
Chithandizo cha mafuta mu ma hpmc
Pazogwiritsidwa ntchito, malo osungunuka ndi kukhazikika kwa ma hpmc ndikofunikira kwambiri. Mwachitsanzo, m'makampani opanga mankhwala, hpmc nthawi zambiri amagwiritsidwa ntchito ngati zinthu kwa makapisozi, zokutira filimu, ndi zonyamula za mankhwala omasulidwa. Mu mapulogalamu awa, kukhazikika kwa matenthedwe ku HPMC kumayenera kukwaniritsa njira zopangira matenthedwe, choncho kumvetsetsa za kutentha kwa marrmal komanso malo osiyanasiyana a HPMC ndikofunikira kuti muchepetse ntchito yopanga.
Mu gawo lomanga, matenda a Evancence®hpm nthawi zambiri amagwiritsidwa ntchito ngati chotsikira mu matope owuma, zofukiza ndi zomatira. Mu mapulogalamu awa, kukhazikika kwa matenthedwe ku HPMC kumafunikiranso mkati mwa magawo ena kuti atsimikizire pakumanga.
Hpmc, ngati zinthu za polymer, sizikhala ndi malo osungunuka, koma zimawonetsedwa ndi mikhalidwe yofalikira ndi pyrolysis mkati mwa kutentha kwina. Malo ake osungunuka nthawi zambiri amakhala pakati pa 200°C ndi 300°C, ndipo malo ena osungunuka amadalira zinthu monga mawonekedwe olemera, digiri ya hydroxyproproproproproproproproproptlaty, digiri ya methylation, ndi chinyezi cha HPMC. Mu zochitika zosiyanasiyana zofunsira, kumvetsetsa zinthu zotentha izi ndikofunikira pakukonzekera ndi kugwiritsa ntchito.
Post Nthawi: Jan-04-2025