Hydroxypropyl methylcellulose (hpmc)ndi mitundu yosinthika yamankhwala yomwe imagwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana monga mankhwala opanga, kupanga chakudya, ndi zomanga. Ndiwophatikizika kosiyanasiyana, nthawi zambiri imagwiritsidwa ntchito ngati thiccener, Bander, wothandizira makanema, ndi okhazikika. Komabe, ilibe "manambala" mwatsatanetsatane, monga chinthu kapena nambala ya gawo yomwe mungapeze muzomwe zimapanga. M'malo mwake, hpmc imazindikiridwa ndi kapangidwe kake ka mankhwala ndi mawonekedwe angapo, monga kuchuluka kwa kulowetsa kapena kukweza.
Zambiri za hydroxypropyl methylcellulose (hpmc)
Kapangidwe ka mankhwala: HPMC imapangidwa ndi kusinthika kwa cellulose yosintha kudzera mu cysroxyl (-oh) magulu a hydroxypyl ndi methyl. Cholowa chimatsitsira katundu wa cellulose, ndikupangitsa kukhala osungunuka m'madzi ndikuupereka mawonekedwe ake apadera ngati luso lopanga mafilimu, opatsa mphamvu kusunga chinyezi.
Zizindikilo wamba ndi kutchula
Chizindikiritso cha hydroxypropyl methylcellulose nthawi zambiri amadalira misonkhano yosiyanasiyana yomwe imafotokoza kapangidwe kake ndi katundu:
Nambala ya Cas:
Kugwiritsa ntchito mankhwala osokoneza bongo (Cas) amapereka chizindikiritso chapadera kwa chilichonse cha mankhwala. Nambala ya cas ya hydroxypropyll methylcellulose ndi 9004-65-3. Iyi ndi nambala yokhazikika yogwiritsidwa ntchito ndi akatswiri azamankhwala, ogulitsa, ndi matupi owongolera kutanthauza chinthucho.
Inchi ndikumwetulira makanema:
Inchi (kuzindikiritsa mankhwala kwapadera) ndi njira ina yoyimira kapangidwe kake ka chinthu. HPMC ikhoza kukhala ndi chingwe cha itchi chomwe chikuyimira mawonekedwe ake molecular.
Kumwetulira (kovuta kusinthasintha kwa mzere wolowetsa) ndi dongosolo linanso lomwe limagwiritsidwa ntchito kuyimira mamolekyulu mu mawonekedwe. HPMC ilinso ndi code yofananira, ngakhale ikhale yovuta kwambiri chifukwa cha mawonekedwe akulu ndi osinthika.
Zithunzi Zogulitsa:
Mu msika wamalonda, hpmc nthawi zambiri amadziwika ndi manambala, omwe amatha kusiyanasiyana ndi wopanga. Mwachitsanzo, wogulitsa akhoza kukhala ndi kalasi ngati HPMC K4M kapena HPMC E15. Zizindikiritso izi nthawi zambiri zimatanthauzira mamasukidwe a polymer mu yankho, lomwe limatsimikiziridwa ndi digiri ya methylation ndi hydroxypropropropropropropropropropropropropyt komanso kunenepa kwambiri.
Magulu wamba a hydroxypropyl methylcellulose (hpmc)
Makhalidwe a hydroxypropyll a methylcellulose amasiyanasiyana malinga ndi kuchuluka kwa magulu a methyl ndi ma hydroxypyl, komanso kunenepa kwambiri. Izi zimatsimikizira kusokonekera kwa HPMC ndi kusungunuka m'madzi, zomwe zimakhudza ntchito zake m'makampani osiyanasiyana.
Pansipa pali gome lomwe limafotokoza za ma grade osiyanasiyana a hydroxypropyl methylcellulose:
| Giledi | Makulidwe (CP mu 2% yankho) | Mapulogalamu | Kaonekeswe |
| Hpmc k4m | 4000 - 6000 cp | Ma piritsi la mankhwala opangira mankhwala, malonda azakudya, zomanga (zomata) | Kalasi yamafayilo yamafayilo yapakatikati, yomwe nthawi zambiri imagwiritsidwa ntchito mu matebulo a pakamwa. |
| Hpmc k100m | 100,000 - 150,000 cp | Mapangidwe oletsedwa-amasulidwa mu mankhwala, zomangamanga, ndi zokutira | Maonekedwe apamwamba, abwino kwambiri kuti atulutsidwe mankhwala. |
| Hpmc e4m | 3000 - 4500 cp | Zodzikongoletsera, zimbudzi, kukonza chakudya, kumamatira, ndi zokutira | Sungunulani m'madzi ozizira, ogwiritsidwa ntchito pazinthu zamwini ndi zinthu zina. |
| Hpmc e15 | 15,000 cp | Kukula kwamphamvu mu utoto, zokutira, chakudya, ndi mankhwala opangira mankhwala | Maonekedwe apamwamba, osungunuka m'madzi ozizira, omwe amagwiritsidwa ntchito m'mafakitale a mafakitale komanso mankhwala. |
| Hpmc m4c | 4000 - 6000 cp | Zakudya ndi zakumwa zakumwa ngati chokhazikika, chogulitsa ngati chomangira | Maonekedwe owoneka bwino, omwe nthawi zambiri amagwiritsidwa ntchito ngati tricker mu chakudya chokonzedwa. |
| Hpmc 2910 | 3000 - 6000 cp | Zodzikongoletsera (zonona, zotupa), chakudya (ceceidery), mankhwala ogulitsa (makapisozi) | Chimodzi mwazikulu zodziwika bwino, zomwe zimagwiritsidwa ntchito ngati chokhazikika komanso kukula. |
| Hpmc 2208 | 5000 - 15000 cp | Amagwiritsidwa ntchito simenti ndi ma pulasitala, zovala, zokutira pepala | Zabwino zogwiritsira ntchito zofunika kwambiri zopanga mafilimu. |
Kupanga mwatsatanetsatane ndi katundu wa HPMC
Mphamvu yakuthupi ya hydroxypropyll methylcellulose zimadalira makamaka kuchuluka kwa magulu a hydroxyl mu celluluse molekyulu. Nayi katundu wamkulu:
Kuchuluka kwa zolowa m'malo (DS):
Izi zikutanthauza kuti magulu ambiri a hydroxyl mu cellulose yalowa m'malo mwa methyl kapena hydroxypyl. Kuchuluka kwa zolowa m'malo kumapangitsa kusungunuka kwa HPMC m'madzi, mamasukidwe ake, komanso kuthekera kwake kupanga mafilimu. Zofanana ndi DS ya HPMC imachokera ku 1.4 mpaka 2.2, kutengera kalasi.
Makulidwe:
Maphunziro a HPMC amagawidwa chifukwa cha mawonekedwe awo akasungunuka m'madzi. Kulemera kwa maselo ndi kuchuluka kwa kulowetsa, ma virus. Mwachitsanzo, HPMC K100m (yokhala ndi ma Isccience apamwamba) nthawi zambiri imagwiritsidwa ntchito popanga mankhwala osokoneza bongo, pomwe otsika ma vincy amagwiritsa ntchito HPMC K4m imagwiritsidwa ntchito pazithunzi za piritsi ndi ntchito.
Kusungunuka kwamadzi:
HPMC imasungunuka m'madzi ndipo imapanga zinthu ngati gel ngati kusungunuka, koma kutentha ndi Ph kumatha kukopa kusandulika kwake. Mwachitsanzo, m'madzi ozizira, imasungunuka msanga, koma kusungunuka kwake kumatha kuchepetsedwa m'madzi otentha, makamaka pamtunda wapamwamba.
Kutha kwa makanema:
Chimodzi mwazinthu zofunikira za hydroxypropyll methylcellulose ndi kuthekera kwake kupanga filimu yosinthika. Katunduyu amapanga zoyenera kugwiritsa ntchito zokutira za piritsi, pomwe pamakhala malo osalala, olamulidwa. Imathandizanso pa malonda azomwe amathandizira kukonza ndi alumali moyo.
Gelation:
Kuzungulira ndi kutentha, hpmc imatha kupanga ma gels. Katunduyu ndi wopindulitsa mu mankhwala opangira mankhwala, komwe amagwiritsidwa ntchito kupanga makina omasulidwa.
Mapulogalamu a hydroxypropyll methylcellulose
Makampani opanga mankhwala:
HPMC imagwiritsidwa ntchito ngati binder mu piritsi, makamaka mumasulidwe ndi makina omasulidwa. Imagwiranso ntchito yolumikizira mapiritsi ndi makapisozi kuti azilamulira kumasulidwa kwa mankhwala othandizira. Kutha kwake kupanga mafilimu okhazikika ndi ma gels ndi abwino kwa makina operekera mankhwala osokoneza bongo.
Makampani Ogulitsa Chakudya
Mu makampani ogulitsa zakudya, hpmc amagwiritsidwa ntchito ngati wothandizila, emulsifier, ndi okhazikika pazogulitsa zosiyanasiyana, kuphatikizapo msuzi, zojambula, zotaphika. Zimathandizira kukonza moyo ndi kuwonjezera alumali moyo mwa kuchepetsa kutaya chinyezi.
Zodzikongoletsera ndi chisamaliro chaumwini:
HPMC imagwiritsidwa ntchito kwambiri modzola, komwe imagwira ngati thickic ndi okhazikika m'madzi, zodzola, shampoos, ndi zinthu zina zosamalira payekha. Kutha kwake kupanga mawonekedwe a gel kumakhala kothandiza kwambiri pamapulogalamuwa.
Makampani omanga:
M'makampani omanga, makamaka mu simenti ndi mapulani a pulasitala, hpmc amagwiritsidwa ntchito ngati wothandizira madzi. Zimathandizira kukonzanso kugwirira ntchito komanso kumawonjezera mgwirizano womwe umagwirizira zida.
Ntchito zina:
HPMC imagwiritsidwanso ntchito pamakampani, zokutira pepala, komanso ngakhale mukupanga mafilimu a biodegradgrad.
Hydroxypropyl methylcellulose (hpmc)ndi malo ophatikizidwa kwambiri omwe amagwiritsidwa ntchito kwambiri chifukwa cha mafakitale angapo chifukwa kuthekera kwake monga luso la mawonekedwe la mafilimu, kuthekera kwakukulitsa, ndi kusungunuka kwamadzi. Ngakhale ilibe "chiwerengero" munthawi yachilendo, chimadziwika ndi mankhwala a Cas Cas (9004-65-3) ndi maphunziro apamwamba (mwachitsanzo, HPMC E4m). Mitundu yosiyanasiyana ya HPMC imapezeka kupezeka mumawonetsedwe ake m'minda yosiyanasiyana, kuchokera pa mankhwala osiyanasiyana, zodzoladzola, zodzoladzola, ndi zomangamanga.
Post Nthawi: Mar-21-2025