Ubushinwa Bwinshi Hypromellose E5, E15, E50 Hydroxypropyl Methyl Cellulose HPMC ya Tablet na Coating
"Ubunyangamugayo, guhanga udushya, imbaraga, no gukora neza" bizaba igitekerezo cy’isosiyete yacu mu gihe kirekire cyo gushinga hamwe n’abakiriya kugira ngo basabane kandi bungurane inyungu ku Bushinwa Hipromellose E5, E15, E50 Hydroxypropyl Methyl Cellulose HPMC kuri Tablet na Coating, Isosiyete yacu yazamutse cyane mu bunini no mu zina ry’ibicuruzwa byinshi.
"Ubunyangamugayo, guhanga udushya, imbaraga, no gukora neza" bizaba igitekerezo gihoraho cyikigo cyacu mugihe kirekire cyo gushinga hamwe nabakiriya kugirango basubiranamo kandi bunguka inyungu kuriHPMC na Hydroxypropyl Methyl Cellulose, Kwizerwa nibyo byihutirwa, kandi serivisi nubuzima. Turasezeranya ko ubu dufite ubushobozi bwo gutanga ibintu byiza kandi byiza byigiciro kubakiriya. Hamwe natwe, umutekano wawe uremewe.
Ibisobanuro ku bicuruzwa
AnxinCel® Hydroxypropyl Methyl Cellulose (HPMC)
Inzira ya molekulari
Hypromellose (Hydroxypropylmethylcellulose: HPMC) ubwoko bwasimbuye 2910, 2906, 2208 (USP)
Ibyiza byumubiri
- Ifu yera cyangwa umuhondo ifu yera
- Gushonga muburyo buvanze kama cyangwa amazi yo mumazi
- Gukora firime ibonerana mugihe solvent ikuraho
- Nta reaction ya chimique hamwe nibiyobyabwenge bitewe numutungo utari ionic
- Uburemere bwa molekuline: 10,000 ~ 1.000.000
- Ingingo ya Gel: 40 ~ 90 ℃
- Auto-ignition Ingingo: 360 ℃
Hydroxypropyl Methylcellulose (HPMC) Urwego rwa Pharmaceutical Grade ni Hypromellose yimiti yimiti ninyongera, ishobora gukoreshwa nkibibyimbye, ikwirakwiza, emulisiferi na agent ikora firime.
AnxinCel® Cellulose ether igizwe na methyl selulose (USP, EP, BP, CP) nubwoko butatu bwo gusimbuza hydroxypropyl methyl selulose (hypromellose USP, EP, BP, CP) buri kimwe kiboneka mubyiciro byinshi bitandukanye mubyiza.
Mubikorwa byo gukora, ipamba karemano isukuye cyane ihindurwamo methyl chloride cyangwa hamwe na methyl chloride ya methyl na oxyde ya propylene kugirango ibe amazi ashonga, ether ya ionic selile. Nta mutungo winyamanswa ukoreshwa mugukora HPMC.HPMC irashobora gukoreshwa nkumuhuza kumiterere ya dosiye ikomeye nka tableti na granules. Ikora kandi imirimo itandukanye, kurugero, mukuzamura amazi, kubyimba, gukora nka colloide ikingira bitewe nubuso bwayo, gukomeza gusohora, no gukora firime.
AnxinCel® HPMC itanga imirimo itandukanye nko kubika amazi, kurinda colloid, ibikorwa byo hejuru, kurekura bikomeje. Nibikoresho bitari ionic birwanya umunyu kandi bihamye hejuru ya pH-intera. Porogaramu zisanzwe za HPMC ni zihuza kumiterere ya dosiye ikomeye nka tableti na granules cyangwa kubyimbye kubisaba amazi.
Pharma HPMC ije ifite ubukonje butandukanye buri hagati ya 3 na 200.000 cps, kandi irashobora gukoreshwa cyane mugusiga ibinini, granulation, binder, kubyimbye, stabilisateur no gukora capsule yimboga HPMC.
Imiterere ya Shimi
| Hypromellose Ibisobanuro | 60E (2910) | 65F (2906) | 75K (2208) |
| Ubushyuhe bwa gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Igisubizo) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000.100000,150000,200000 | ||
Urwego rwibicuruzwa
| Hypromellose Ibisobanuro | 60E (2910) | 65F (2906) | 75K (2208) |
| Ubushyuhe bwa gel (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity (cps, 2% Igisubizo) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000.100000,150000,200000 | ||
Gusaba
Pharma Grade HPMC ituma umusaruro wibikorwa bigenzurwa-kurekura byoroshye uburyo bukoreshwa cyane bwa tablet-binding. Urwego rwa Pharma rutanga ifu nziza, guhuza ibirimo, hamwe no guhuzagurika, bigatuma bikwirakwira neza.
| Gusaba Farma Gusaba | Icyiciro cya Farma HPMC | Umubare |
| Ibibyimba byinshi | 75K4000.75K100000 | 3-30% |
| Amavuta, Gels | 60E4000.75K4000 | 1-5% |
| Gutegura amaso | 60E4000 | 01.-0.5% |
| Amaso atonyanga imyiteguro | 60E4000 | 0.1-0.5% |
| Guhagarika Umukozi | 60E4000, 75K4000 | 1-2% |
| Antacide | 60E4000, 75K4000 | 1-2% |
| Guhuza ibinini | 60E5, 60E15 | 0.5-5% |
| Amasezerano atose | 60E5, 60E15 | 2-6% |
| Ibikoresho bya Tablet | 60E5, 60E15 | 0.5-5% |
| Kugenzura Kurekura Matrix | 75K100000,75K15000 | 20-55% |
Ibiranga inyungu
- Kunoza ibiranga ibicuruzwa
- Kugabanya ibihe byo gutunganya
- Umwirondoro umwe, uhamye wo gusesa
- Itezimbere uburinganire
- Kugabanya ibiciro byumusaruro
- Igumana imbaraga zingana nyuma yo gukuba kabiri (roller compaction) inzira
Gupakira
Gupakira bisanzwe ni 25kg / ingoma
20'FCL: toni 9 hamwe na palletised; Toni 10 idashyizwe ahagaragara.
40'FCL: toni 18 hamwe na palletised; Toni 20 idashyizwe ahagaragara. n'abakiriya bakomeye.
UbushinwaHPMC na Hydroxypropyl Methyl Cellulose, Kwizerwa nibyo byihutirwa, kandi serivisi nubuzima. Turasezeranya ko ubu dufite ubushobozi bwo gutanga ibintu byiza kandi byiza byigiciro kubakiriya. Hamwe natwe, umutekano wawe uremewe.
