HydroxyPropyl MethylcellAlose (HPMC) na HYPROMMELLOSE rwose ni urujijo kimwe, kandi amagambo akoreshwa muburyo bumwe. Izi ni amazina atoroshye yubwoko busanzwe bwa polmers bishingiye kuri selile bifitanye isano nini mubikorwa bitandukanye birimo farumasi, ibiryo no kwisiga.
1.Imiterere n'imiterere:
HydroxyPropylmethylcellcellCellsellsellsells (HPMC) ni uguhindura sinishidie ya selire, polymer karemano iboneka mu nkike za serile. Imiterere yimiti ya HPMC iboneka mugutangiza amatsinda ya hydroxyle na methyl hashingiwe kuri selile. Itsinda rya HydroxyPropyl rituma selile ikomeretsa mumazi, kandi methyl itsinda ryongerera umutekano kandi rigabanya uko byagenda.
2. Igikorwa cyo Gukora:
Umusaruro wa HydroxyPropyl Methylcellse urimo kuvura oxide ya propay kugirango utangire amatsinda ya hydroxyProyle hanyuma hamwe na methyl chloride kugirango wongere amatsinda ya methyl. Urwego rwo gusimbuza (DS) rwa HydroxyPropyl na methyl irashobora guhinduka mugihe cyo gukora, bikaviramo amanota atandukanye ya HPMC ifite ibintu bitandukanye.
3. Imiterere yumubiri:
HPMC niyera kuri ifu yera gato-yera, impumuro nziza kandi itaryoshye. Ibintu byayo byumubiri, nka viscosity no kudusimburwa, biterwa nurwego rwo gusimbuza nuburemere bwa moleclar bwa polymer. Mubihe bisanzwe, birashonga byoroshye mumazi, gukora igisubizo kiboneye kandi kitagira ibara.
4. Intego z'ubuvuzi:
Imwe mubyiciro nyamukuru bya HPMC biri mu nganda za farumasi. Bikoreshwa cyane nka farumasi ya farumasi kandi tukagira uruhare rutandukanye rwimyiteguro ya farumasi. HPMC ikunze kuboneka mumiterere ya dosiye ikomeye nka tableti, capsules, nibinini. Ikora nka bunder, induru, kandi igenzurwa numukozi urekura, atanga umusanzu mubintu rusange na bioatseilability yibiyobyabwenge.
5. Uruhare rwo Kugenzurwa Imyiteguro yo kurekura:
Ubushobozi bwa HPMC kugirango bugire amavuta mubisubizo bitangaje bituma bifite agaciro kugenzurwa-kurekura ibiyobyabwenge. Muguhindura vicosity na gel imiterere ya gel, abahanga mu bubabare barashobora kugenzura igipimo cyo kurekura ibintu bifatika, bityo bakagera kubikorwa byarakaye kandi bimaze igihe.
6. Gusaba inganda zibiribwa:
Mu nganda zibiribwa, HPMC ikoreshwa nkuwabyimbye, Stabilizer na Emalisiier. Itezimbere imiterere yibiryo bitandukanye, harimo isosi, isupu nibikomoka ku mata. Byongeye kandi, HPMC ikoreshwa mu guteka ku buntu ku buntu kugira ngo iteze imbere imiterere n'imiterere y'ibicuruzwa bidahwitse.
7. Ibikoresho byo kubaka no kubaka:
HPMC ikoreshwa mu nganda zubwubatsi mubicuruzwa nka tile ashimishijwe, impongano zishingiye kuri sima hamwe nibikoresho bishingiye ku banyarwanda. Itezimbere itunganijwe, kugumana amazi hamwe nibikorwa bifatika byibi bicuruzwa.
8. Amavuta yo kwisiga hamwe nibicuruzwa byita kugiti cyawe:
Hypromellose nayo ni ikintu gisanzwe muri kwisiga no kwitonda. Ikoreshwa muri cream, amavuta na shampoos kubera kubyimba no guhungabanya umutekano. Byongeye kandi, bifasha kunoza imiterere rusange no kumva ibicuruzwa.
9. Filime ihinga muri farumasi:
HPMC ikoreshwa cyane mu nganda za farumasi kugirango ikore film. Ibinini bya firime bitanga isura nziza, uburyohe bwo kwihisha no kurinda ibintu bidukikije. Filime za HPMC zitanga ipfundo ryoroshye kandi rimwe, utezimbere ubuziranenge bwibicuruzwa.
13. Umwanzuro:
HydroxyPropyl MethylcellALese (HPMC) na HYPROMMELLOSE bivuga polymer imwe ishingiye kuri selile ifite ibintu bitandukanye muri faruceticals, ibiryo, kwisiga, no kubaka. Umutungo wacyo wihariye, nko gukurura, gushikama no biodegradavidalitire, bigira uruhare mugukoresha cyane. Guhindura HPMC mu nganda zitandukanye byerekana akamaro kayo nkibikoresho byinshi, kandi bikomeza reGushakisha niterambere birashobora kuvura porogaramu zinyongera mugihe kizaza.
Iyi mirongo yuzuye igamije gutanga ibisobanuro birambuye kuri hydroxyproppopyl methylcellus na hypromlllose, kandi isomera akamaro kabo mumirima itandukanye, kandi isomera uruhare rwabo mugutegambere ibicuruzwa hamwe nibikorwa byinshi.
Igihe cyo kohereza: Ukuboza-21-2023